Pax6 influences expression patterns of genes involved in neuro- degeneration.
Benares, India. In Ann Neurosci, Oct 2015
RESULTS: The levels of expression of transcripts of some of the proposed putative markers of neurodegeneration like Pax6, S100β, GFAP, BDNF, NGN2, p73α, p73δ, LDH, SOD, and Catalase were analyzed in Pax6 knockdown condition for analysis of role of Pax6 in neurodegeneration.
Proneural genes in neocortical development.
Calgary, Canada. In Neuroscience, 2014
In particular, we focus on the proneural genes Neurogenin 1 (Neurog1), Neurog2 and Achaete scute-like 1 (Ascl1), which are each expressed in a distinct fashion in the progenitor cell pools that give rise to all of the neuronal and glial cell types of the mature neocortex.
bHLH genes and retinal cell fate specification.
Birmingham, United States. In Mol Neurobiol, 2005
Photoreceptor genesis appears to employ two transcriptional pathways: ngn2-->neuroD-->raxL and ath5-->neuroD-->raxL. ngn2 and ath5 function in progenitors, which can potentially develop into different cell types.