Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage.more suppliers
In PLoS ONE, 2007
... factors and chemicals were obtained from the following manufacturers: FGF1, FGF2, WNT3a, WNT5a, DKK1, EGF, NGF (R&D Systems, Minneapolis, MN); heparin (Invitrogene); wortmannin, LY294002, U0126 (Cell Signaling, Beverly, MA); tunicamycin (Enzo ...
Osteoarthritis year in review 2015: clinical.
Chicago, United States. In Osteoarthritis Cartilage, Jan 2016
Symptom outcomes of pharmacologic treatments were reported for methotrexate, adalimumab, anti-nerve growth factor monoclonal antibodies, strontium ranelate, bisphosphonates, glucosamine, and chondroitin sulfate, and structural outcomes of pharmacologic treatments for strontium ranelate, recombinant human fibroblast growth factor 18, and glucosamine and chondroitin sulfate.
Acute versus chronic phase mechanisms in a rat model of CRPS.
Palo Alto, United States. In J Neuroinflammation, Dec 2015
The expression of the neuropeptide signaling molecule substance P (SP), NK1 receptor, inflammatory mediators TNFα, IL-1β, and IL-6 and nerve growth factor (NGF) were elevated at 4 weeks in sciatic nerve and/or skin, returning to normal levels by 16 weeks post fracture.
Modulation of neurotrophic signaling pathways by polyphenols.
Shīrāz, Iran. In Drug Des Devel Ther, Dec 2015
Assessment of underlying mechanisms, especially in PC12 neuronal-like cells, reveals that direct agonistic effect on tropomyosin receptor kinase (Trk) receptors, the main receptors of neurotrophic factors including nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) explains the action of few polyphenols such as 7,8-dihydroxyflavone.
Neurotrophin regulation of neural circuit development and function.
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Berkeley, United States. In Nat Rev Neurosci, 2013
Brain-derived neurotrophic factor (BDNF)--a member of a small family of secreted proteins that includes nerve growth factor, neurotrophin 3 and neurotrophin 4--has emerged as a key regulator of neural circuit development and function.
Capsaicin receptor in the pain pathway
In Environmental Health Perspectives, 1999
... Nerve growth factor in standard and samples was bound to an anti-NGF mouse monoclonal antibody coated onto a BD Falcon 96-well microplate (BD Biosciences, Bedford, MA, USA) ... UniGene
In Genome Biology, 1998
... in Leibovitz modified L15 medium (Gibco BRL) supplemented with 2% horse serum and 150 ng/ml NGF (grade II; Alomone Labs, Jerusalem, Israel) as previously ...