Neurotrophins and Neuropathic Pain: Role in Pathobiology.
Brisbane, Australia. In Molecules, 2014
nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 and neurotrophin 4. Most research on NTs to date has focussed on the effects of NGF and BDNF signalling via their respective cognate high affinity neurotrophic tyrosine kinase viz TrkA and TrkB receptors.
Brain-Derived Neurotrophic Factor: Three Ligands, Many Actions.
New York City, United States. In Trans Am Clin Climatol Assoc, 2014
Brain-derived neurotrophic factor (BDNF) is a member of a family of neurotrophins which include nerve growth factor, neurotrophin 3, and neurotrophin 4. Studies over the last three decades have identified mature BDNF as a key regulator of neuronal differentiation, structure, and function; actions mediated by the TrkB receptor.
Neurotrophin regulation of neural circuit development and function.
Berkeley, United States. In Nat Rev Neurosci, 2013
Brain-derived neurotrophic factor (BDNF)--a member of a small family of secreted proteins that includes nerve growth factor, neurotrophin 3 and neurotrophin 4--has emerged as a key regulator of neural circuit development and function.