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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Neuropilin 2

neuropilin-2, NARP, NRP2, NP-2
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on neuropilin-2
NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system.
GeneRIF
Ruhrberg et al., London, United Kingdom. In Dev Biol, 2012
Loss of NRP2 or its ligand SEMA3F impaired sympathetic gangliogenesis more mildly than loss of SEMA3A/NRP1 signalling, but caused ectopic neurite extension along the embryonic aorta.
Association study of early-immediate genes in childhood-onset mood disorders and suicide attempt.
GeneRIF
Kennedy et al., Toronto, Canada. In Psychiatry Res, 2012
This study demonistrated that childhood-onset mood disorders and suicide attempt association between HOMER1 rs2290639 and between NPTX2 markers rs705315 and rs1681248.
Structure-function analysis of Nel, a thrombospondin-1-like glycoprotein involved in neural development and functions.
GeneRIF
Nakamoto et al., Aberdeen, United Kingdom. In J Biol Chem, 2012
Nel interacts with a range of molecules through its different domains and exerts distinct functions.
The neuronal EGF-related gene Nell2 interacts with Macf1 and supports survival of retinal ganglion cells after optic nerve injury.
GeneRIF
Piri et al., Los Angeles, United States. In Plos One, 2011
It was shown that Nell2 expression at both mRNA and protein levels is localized to retinal ganglion cells. Nell2 had a molecular weight of ~ 140 kDa and 90 kDa, corresponding to the glycosylated and non-glycosylated form, respectively.
Neuropilin-2 mediated β-catenin signaling and survival in human gastro-intestinal cancer cell lines.
GeneRIF
Ellis et al., Houston, United States. In Plos One, 2010
tumor cell-derived NRP-2 mediates critical survival signaling in gastrointestinal cancer cells
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