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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


Neuroglobin, Ngb
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, Myoglobin, Hgb, V1a, HAD
Papers on Neuroglobin
Neuroglobin immunoreactivity in the human cochlea.
Lopez et al., Los Angeles, United States. In Brain Res, Feb 2016
Neuroglobin (Ngb) is an oxygen-binding protein with a demonstrated role in endogenous neuroprotective mechanisms.
Pichia pastoris Production of Tat-NGB and Its Neuroprotection on Rat Pheochromocytoma Cells.
Zhang et al., Beijing, China. In Mol Biotechnol, Jan 2016
Neuroglobin (NGB) is a newly discovered neuroprotector and mainly localized in the neurons and retinal cells of the central and peripheral nervous systems in vertebrates, and its prokaryotic expression protein of which fused with HIV-1 virus-encoded Tat peptide exhibited significant antioxidant and anti-hypoxia.
Characterization of zebrafish neuroglobin and cytoglobins 1 and 2: Zebrafish cytoglobins reveal functional divergences with mammalian proteins.
Tejero et al., Pittsburgh, United States. In Nitric Oxide, Jan 2016
UNASSIGNED: Neuroglobin (Ngb) and cytoglobin (Cygb) are two six-coordinate heme proteins of unknown physiological function.
Unbiased View of Synaptic and Neuronal Gene Complement in Ctenophores: Are There Pan-neuronal and Pan-synaptic Genes across Metazoa?
Kohn et al., United States. In Integr Comp Biol, Dec 2015
None of the so-called pan-neuronal genes such as embryonic lethal abnormal vision (ELAV), Musashi, or Neuroglobin are expressed exclusively in neurons of the ctenophore Pleurobrachia.
A Possible Role of Neuroglobin in the Retina After Optic Nerve Injury: A Comparative Study of Zebrafish and Mouse Retina.
Kato et al., Kanazawa, Japan. In Adv Exp Med Biol, Dec 2015
Neuroglobin (Ngb) is a new member of the family of heme proteins and is specifically expressed in neurons of the central and peripheral nervous systems in all vertebrates.
Dopamine D3 receptor binding of (18) F-fallypride: Evaluation using in vitro and in vivo PET imaging studies.
Pan et al., Irvine, United States. In Synapse, Dec 2015
Rat slices were also treated with BP 897 (68-fold D3R selective partial agonist) and NGB 2904 (56-fold D3R selective antagonist).
Dopamine D3 receptor antagonism contributes to blonanserin-induced cortical dopamine and acetylcholine efflux and cognitive improvement.
Meltzer et al., Chicago, United States. In Pharmacol Biochem Behav, Nov 2015
Here we determined the ability of blonanserin, the D3 antagonist NGB 2904, and the typical APD, haloperidol, a D2 antagonist, to enhance neurotransmitter efflux in the medial prefrontal cortex (mPFC) and dSTR of mice, and to ameliorate the scPCP-induced deficit in NOR in rats.
Retinal oxygen distribution and the role of neuroglobin.
Byrne et al., Oxford, United Kingdom. In J Math Biol, Oct 2015
It has been suggested that the protein neuroglobin (Ngb), which is found in high concentrations within the retina, may help to maintain an adequate supply of oxygen via the processes of transport and storage.
Effects of intermittent hypobaric hypoxia preconditioning on the expression of neuroglobin and Bcl-2 in the rat hippocampal CA1 area following ischemia-reperfusion.
Liu et al., Xining, China. In Genet Mol Res, 2014
This study was aimed at understanding the effect of intermittent hypobaric hypoxia preconditioning (IHHP) on neuroglobin (NGB) and Bcl-2 expression in the hippocampal CA1 region of rats following global cerebral ischemia-reperfusion. Wistar rats were randomly divided into sham, IHHP control, global cerebral ischemia-reperfusion (IR group), and IHHP+IR groups.
Neuroglobin - recent developments.
Chen et al., In Biomol Concepts, 2014
Neuroglobin (Ngb), a monomeric hexacoordinated heme protein of 17 kDa, was identified in 2000 in the nervous system.
Use of vanilloids in urologic disorders.
Lake et al., In Prog Drug Res, 2013
This chapter examines the literature describing the use of vanilloid receptor agonists in the treatment of the following urological disorders: neurogenic bladder (NGB), overactive bladder (OAB), and interstitial cystitis/painful bladder syndrome (IC/PBS).
Structure and function of heme proteins in non-native states: a mini-review.
Wang et al., Hengyang, China. In J Inorg Biochem, 2013
Although adopting proper native states is very important for these functions, progresses in representative heme proteins, including cytochrome c (cyt c), cytochrome b5 (cyt b5), myoglobin (Mb), neuroglobin (Ngb), cytochrome P450 (CYP) and heme-based sensor proteins such as CO sensor CooA, showed that various native functions, or new functions evolved, are also closely associated with non-native states.
[Recent advances in study of neuroglobin expression in retinal diseases].
Li et al., Beijing, China. In Zhonghua Yan Ke Za Zhi, 2013
Neuroglobin (NGB) is widely exists in the retina and predominantly expressed in the plexiform layers and the inner segments.
Mitochondrial mechanisms of neuroglobin's neuroprotection.
Wang et al., United States. In Oxid Med Cell Longev, 2012
Neuroglobin (Ngb) is an oxygen-binding globin protein that has been demonstrated to be neuroprotective against stroke and related neurological disorders.
Human neuroglobin functions as an oxidative stress-responsive sensor for neuroprotection.
Wakasugi et al., Tokyo, Japan. In J Biol Chem, 2012
the oxidative stress-induced structural changes of human Ngb are essential for its neuroprotective activity.
Mitochondrial distribution of neuroglobin and its response to oxygen-glucose deprivation in primary-cultured mouse cortical neurons.
Wang et al., United States. In Neuroscience, 2012
mitochondria distribution of Ngb is clearly associated with and may contribute to Ngb's neuroprotection.
Acute hypoxia modifies regulation of neuroglobin in the neonatal mouse brain.
Trollmann et al., Erlangen, Germany. In Exp Neurol, 2012
Cerebral regulation of neuroglobin is related to maturational stage; hypoxia-induced neuroglobin up-regulation is modified by the hypoxia-inducible transcription factor (HIF) system.
Interactions between vascular endothelial growth factor and neuroglobin.
Greenberg et al., Novato, United States. In Neurosci Lett, 2012
VEGF stimulated Ngb expression in a VEGFR2/Flk1 receptor-dependent manner, whereas Ngb overexpression suppressed expression of VEGF.
Circadian behaviour in neuroglobin deficient mice.
Hannibal et al., Copenhagen, Denmark. In Plos One, 2011
Genetic elimination of neuroglobin evokes an increased behavioural response to light concomitant with increased Per1 gene expression in the suprachiasmatic nucleus.
A vertebrate globin expressed in the brain.
Hankeln et al., Mainz, Germany. In Nature, 2000
The paper describes the discovery of neuroglobin, the oxygen-binding properties (P50 = 1-2 Torr), and its preferential expression in the mouse brain.
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