Gene Expression in HIV-Associated Neurocognitive Disorders: A Meta-Analysis.
Richmond, United States. In J Acquir Immune Defic Syndr, Jan 2016
Strong examples of the highly upregulated genes were PSMB8-AS1, APOL6, TRIM69, PSME1, CTSB, HLA-E, GPNMB, UBE2L6, PSME2, NET1, CAPG, B2M, RPL38, GBP1, and PLSCR1.
Perioperative propofol-paravertebral anesthesia decreases the metastasis and progression of breast cancer.
Nanjing, China. In Tumour Biol, Nov 2015
Among them, PPA participates in several bioprocesses in the development of breast cancer, including inhibiting hypoxia-inducible factor (HIF) activity, elevating serum concentration of nitric oxide index (NOx), depression of the neuroepithelial cell transforming gene 1 (NET1) signal pathway, blocking the nuclear factor kappa B (NF-κB) pathway following an decreased expression of matrix metalloproteinase (MMP), increasing NK cytotoxicity, and affecting transforming growth factor (TGF)-β-targeted ras and HER2/neu gene pathways.
Expression patterns of immune-associated genes in external genital and perianal warts treated with sinecatechins.
Houston, United States. In Viral Immunol, May 2015
Genes that were significantly regulated between VRs and VNRs were CREB3L4, HIST1H3A, HIST1H3H, IFNA1, IFNA4, IFNA5, IFNA6, IFNA8, IFNA14, IFNG, IFNAR1, IL6, IRF9, MAPK4, MAPK5, MAPK14, NET1, and PIK3C2A in the IFN array.
Deficiency of Sustained Attention in ADHD and Its Potential Genetic Contributor MAOA.
Beijing, China. In J Atten Disord, Apr 2015
OBJECTIVE: To investigate the genetic contributors to ADHD sustained attention deficit among noradrenergic genes responsible for the synthesis (dopamine-β-hydroxylase gene, DBH), transport (norepinephrine transporter gene, NET1), reception (alpha-2A adrenergic receptor gene, ADRA2A), and metabolism (monoamine oxidase A gene, MAOA) of noradrenalin (NE).
The RhoGEF Net1 is required for normal mammary gland development.
Houston, United States. In Mol Endocrinol, 2014
Neuroepithelial transforming gene 1 (Net1) is a RhoA subfamily-specific guanine nucleotide exchange factor that is overexpressed in human breast cancer and is required for breast cancer cell migration and invasion.