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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 27 Feb 2015.

Nestin

nestin
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011] (from NCBI)
Top mentioned proteins: CAN, Glial Fibrillary Acidic Protein, HAD, Sox2, vimentin
Papers using nestin antibodies
Dicer1 functions as a haploinsufficient tumor suppressor.
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Reh Thomas A., In PLoS ONE, 2008
... Nestin-Cre transgenic mice ...
The diseasome of physical inactivity–and the role of myokines in muscle–fat cross talk.
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Rota Marcello, In PLoS ONE, 2008
... Nestin-GFP transgenic mice were maintained as ...
Variation in the safety of induced pluripotent stem cell lines.
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Amédée Thierry, In PLoS ONE, 2008
... Nestin-EGFP transgenic mice carry enhanced green ...
NG2 cells generate both oligodendrocytes and gray matter astrocytes
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Kempermann Gerd et al., In Cell and Tissue Research, 2007
... The generation of the Nestin-green fluorescent protein (GFP) transgenic mice was as previously ...
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Papers on nestin
The Effect of Acori graminei Rhizoma and Extract Fractions on Spatial Memory and Hippocampal Neurogenesis in Amyloid Beta 1-42 Injected Mice.
New
Li et al., Guangzhou, China. In Cns Neurol Disord Drug Targets, 25 Mar 2015
Levels of Aβ1-42 and expressions of doublecortin and nestin in the hippocampus were examined using immunohistochemistry.
Microtubule-associated protein tau (Mapt) is expressed in terminally differentiated odontoblasts and severely down-regulated in morphologically disturbed odontoblasts of Runx2 transgenic mice.
New
Komori et al., Nagasaki, Japan. In Cell Tissue Res, 24 Mar 2015
Odontoblasts show severe reductions in Dspp and nestin expression and lose their characteristic polarized morphology, including a long process extending to dentin, in Tg(Col1a1-Runx2) mice.
Improvement in the neural stem cell proliferation in rats treated with modified "Shengyu" decoction May contribute to the neurorestoration.
New
Wang et al., Nantong, China. In J Ethnopharmacol, 19 Mar 2015
The levels of nerve growth-related factors GDNF, NGF, NCAM, TN-C, and Nogo-A and the number of GFAP(+)/GDNF(+), BrdU(+)/nestin(+), BrdU(+)/NeuN(+) immunoreactive cells in the brain ipsilateral to TBI were also measured.
Donepezil Rescues Spatial Learning and Memory Deficits following Traumatic Brain Injury Independent of Its Effects on Neurogenesis.
New
Kernie et al., New York City, United States. In Plos One, Dec 2014
By coupling donepezil therapy with temporally regulated ablation of injury-induced neurogenesis using nestin-HSV transgenic mice, we investigated whether the pro-cognitive effects of donepezil following injury might occur through increasing neurogenesis.
Neural stem/progenitor cells react to non-glial cns neoplasms.
New
Litofsky et al., Columbia, United States. In Springerplus, Dec 2014
We identified neural stem/progenitor cells using standard immunohistochemical markers thereof, including CD133, nestin, Group II Beta-tubulin, Musashi1, and the transcription factor Sox2, in neurosurgically obtained specimens of NHL-CNS metastatic carcinoma , and metastatic melanoma .
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms.
New
Impact
Méndez-Ferrer et al., Madrid, Spain. In Nature, Sep 2014
We previously showed that bone marrow nestin(+) mesenchymal stem cells (MSCs) innervated by sympathetic nerve fibres regulate normal HSCs.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
New
Impact
Lowe et al., New York City, United States. In Cell, Aug 2014
Here, we show that p53 restricts expression of the stem and progenitor-cell-associated protein nestin in an Sp1/3 transcription-factor-dependent manner and that Nestin is required for tumor initiation in vivo.
"Gliomatosis encephali" as a novel category of brain tumors by the first autopsy case report of gliomatosis cerebelli.
Review
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Oyanagi et al., Nagano, Japan. In Neuropathology, Jun 2014
Neuropathological examination identified the tumor cells as being positive for glial fibrillary acidic protein, vimentin and nestin, with atypical nuclei that were cashew-nut- or dishcloth-gourd-shaped.
Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation.
New
Impact
Nagasawa et al., Kyoto, Japan. In Nature, May 2014
Many studies have identified diverse candidate cells that constitute niches for haematopoietic stem cells in the marrow, including osteoblasts, endothelial cells, Schwann cells, α-smooth muscle actin-expressing macrophages and mesenchymal progenitors such as CXC chemokine ligand (CXCL)12-abundant reticular (CAR) cells, stem cell factor-expressing cells, nestin-expressing cells and platelet-derived growth factor receptor-α (PDGFR-α)(+)Sca-1(+)CD45(-)Ter119(-) (PαS) cells.
Direct measurement of local oxygen concentration in the bone marrow of live animals.
New
Impact
Lin et al., Boston, United States. In Nature, May 2014
The endosteal region, by contrast, is less hypoxic as it is perfused with small arteries that are often positive for the marker nestin.
[Bone and Stem Cells. Bone marrow microenvironment niches for hematopoietic stem and progenitor cells].
Review
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Nagasawa, Kyoto, Japan. In Clin Calcium, Apr 2014
The identity and functions of various other candidate HSC niche cells, including nestin-expressing cells and Schwann cells would also be discussed in this review.
Neuroimmmune interactions of cannabinoids in neurogenesis: focus on interleukin-1β (IL-1β) signalling.
Review
Molina-Holgado et al., Toledo, Spain. In Biochem Soc Trans, 2013
NSCs express functional CB1 and CB2 cannabinoid receptors, DAGLα (diacylglycerol lipase α) and the NSC markers SOX-2 and nestin.
Histopathological determinants of tumor resistance: a special look to the immunohistochemical expression of carbonic anhydrase IX in human cancers.
Review
Staibano et al., Napoli, Italy. In Curr Med Chem, 2013
We reviewed the current data concerning the role of CA IX overexpression in human malignancies, extending such information to the expression of the stem cells markers CD44 and nestin in solid cancers, to explore their relationship with the biological behavior of tumors.
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.
Impact
Cao et al., Baltimore, United States. In Nat Med, 2013
High concentrations of TGF-β1 induced formation of nestin-positive mesenchymal stem cell (MSC) clusters, leading to formation of marrow osteoid islets accompanied by high levels of angiogenesis.
Prognostic impact of nestin expression in resected large cell neuroendocrine carcinoma of the lung.
GeneRIF
Masuda et al., Japan. In Lung Cancer, 2012
The present study suggests that nestin expression seems to be a prognostic indicator of a poorer survival probability in patients with resected LCNEC, although its prognostic significance still requires confirmation with larger patient populations.
Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer.
GeneRIF
Naito et al., Tokyo, Japan. In Int J Oncol, 2012
Nestin was not localized in the squamous epithelium in normal cervical tissues, but it was weakly expressed in the basal squamous epithelium in cervical intraepithelial neoplasia
Nestin and other putative cancer stem cell markers in pancreatic cancer.
Review
GeneRIF
Ishiwata et al., Tokyo, Japan. In Med Mol Morphol, 2012
Studies suggest that nestin may modulate the invasion and metastasis of nestin-positive progenitor cells during pancreatic ductal adenocarcinoma (PDAC) development and may serve as a novel target for suppressing invasion and metastasis in PDAC.
Expression patterns of nestin and dentin sialoprotein during dentinogenesis in mice.
GeneRIF
Ohshima et al., Niigata, Japan. In Biomed Res, 2012
Preodontoblasts began to express nestin and Dsp proteins and Dsp mRNA, which increased in their intensity according to the progress of odontoblast differentiation in both incisors and developing molars
Stem cell markers aldehyde dehydrogenase type 1 and nestin expressions in renal cell cancer.
GeneRIF
Somay et al., İstanbul, Turkey. In Arch Ital Urol Androl, 2012
Nestin expression was higher in tumor tissues of renal cell carcinoma, than normal tissues (p < 0.05). Nestin expression was inversely related with tumor stage (p < 0.05) but there was no relation with Fuhrman grade.
Dopamine neuron generation from human embryonic stem cells.
Review
Park et al., Ch'ŏnan, South Korea. In Int J Stem Cells, 2011
Using this protocol, the majority of differentiated hES cells contained nestin positive cells (>95%) and after final differentiation a high percentage of TuJ1 positive neurons was tyrosine hydroxylase positive (>40%).
More papers using nestin antibodies
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity
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Moore Darren J et al., In Molecular Neurodegeneration, 2006
... ] and nestin-Cre [36] transgenic mice were maintained on ...
Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice.
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Hatfield Dolph L., In PLoS ONE, 2005
... were crossed with Nestin-Cre transgenic mice ...
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
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Morrison Sean J. et al., In Nature, 2002
... Nestin-Cherry transgenic mice ...
Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein.
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Borlongan Cesario V., In PLoS ONE, 2001
... Before conducting any experiments, mGFAP-eGFP or nestin-GFP [55] transgenic mice were deeply anesthetized ...
Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide
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Condie Brian G. et al., In The Journal of Cell Biology, 2000
... Anti-nestin mouse monoclonal IgG (clone Rat 401) was from BD Biosciences, and monoclonal anti-ceramide mouse ...
Inhibitor of neurite outgrowth in humans.
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Cookson Mark R., In PLoS ONE, 1999
... beta and α-tubulin (Sigma); P-STAT3 (Ser727), P-STAT3 (Tyr 705) and STAT3 (CST), P-mTOR and mTOR (CST);Nestin (ABCAM) ; Nogo-A (#Nogo-A 12-A, AD);MBP ...
Live astrocytes visualized by green fluorescent protein in transgenic mice
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Bordey Angélique et al., In Frontiers in Neuroscience, 1996
... Neural stem and progenitor cells in nestin-GFP transgenic mice ...
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis.
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Callaerts Patrick, In PLoS ONE, 1994
... Louis, MO); mouse monoclonal anti-nestin (Becton Dickinson, Bedford, MA); mouse monoclonal ...
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