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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 Mar 2014.


This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011] (from NCBI)
Top mentioned proteins: CAN, Glial Fibrillary Acidic Protein, vimentin, Sox2, HAD
Papers using nestin antibodies
Dicer1 functions as a haploinsufficient tumor suppressor.
Reh Thomas A., In PLoS ONE, 2008
... Nestin-Cre transgenic mice ...
The diseasome of physical inactivity–and the role of myokines in muscle–fat cross talk.
Rota Marcello, In PLoS ONE, 2008
... Nestin-GFP transgenic mice were maintained as ...
Variation in the safety of induced pluripotent stem cell lines.
Amédée Thierry, In PLoS ONE, 2008
... Nestin-EGFP transgenic mice carry enhanced green ...
NG2 cells generate both oligodendrocytes and gray matter astrocytes
Kempermann Gerd et al., In Cell and Tissue Research, 2007
... The generation of the Nestin-green fluorescent protein (GFP) transgenic mice was as previously ...
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Papers on nestin
Allogenic tooth transplantation inhibits the maintenance of dental pulp stem/progenitor cells in mice.
Ohshima et al., Niigata, Japan. In Cell Tissue Res, 27 Apr 2014
This study aims to elucidate the influence of allograft on the maintenance of dental pulp stem/progenitor cells following tooth replantation and allo- or auto-genic tooth transplantation in mice using BrdU chasing, immunohistochemistry for BrdU, nestin and Ki67, in situ hybridization for Dspp, transmission electron microscopy and TUNEL assay.
Phases of intermediate filament composition in Bergmann glia following cerebellar injury in adult rat.
Kalman et al., Budapest, Hungary. In Exp Brain Res, 26 Apr 2014
The present study describes the characteristic phases of intermediate filament protein formation during the different stages of BG response following injury and compares them with reactive glial patterns of other brain areas and patterns of glial development.
A spatiotemporal study of gliosis in relation to depth electrode tracks in drug-resistant epilepsy.
Thom et al., London, United Kingdom. In Eur J Neurosci, 26 Apr 2014
Double-labelled immunolabelling using a proliferative cell marker (MCM2), markers of fate-specific transcriptional factors (PAX6, SOX2), a microglial marker (IBA1) and glial markers (nestin, GFAP) was quantified in three regions: zone 1 (immediate vicinity: 0-350 μm), zone 2 (350-700 μm) and zone 3 (remote ≥2000 μm) in relation to the ICE injury site.
Liver X receptor β delays transformation of radial glial cells into astrocytes during mouse cerebral cortical development.
Fan et al., Chongqing, China. In Neurochem Int, 21 Apr 2014
Using nestin as a specific marker for both RG cells and astrocytes, we found that loss of LXRβ caused a reduction in the level of RG fibers and increase in the astrocytes.
MicroRNA-432 contributes to Dopamine cocktail and Retinoic acid induced differentiation of human neuroblastoma cells by targeting NESTIN and RCOR1 genes.
Bhattacharyya et al., Calcutta, India. In Febs Lett, 18 Apr 2014
Among the altered miRNAs, human brain expressed miR-432 induced neurite projections, arrested cells in G0-G1, reduced cell proliferation and could significantly repress NESTIN/NES, RCOR1/COREST and MECP2.
Direct measurement of local oxygen concentration in the bone marrow of live animals.
Lin et al., Boston, United States. In Nature, 02 Apr 2014
The endosteal region, by contrast, is less hypoxic as it is perfused with small arteries that are often positive for the marker nestin.
Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation.
Nagasawa et al., Kyoto, Japan. In Nature, 02 Apr 2014
Many studies have identified diverse candidate cells that constitute niches for haematopoietic stem cells in the marrow, including osteoblasts, endothelial cells, Schwann cells, α-smooth muscle actin-expressing macrophages and mesenchymal progenitors such as CXC chemokine ligand (CXCL)12-abundant reticular (CAR) cells, stem cell factor-expressing cells, nestin-expressing cells and platelet-derived growth factor receptor-α (PDGFR-α)(+)Sca-1(+)CD45(-)Ter119(-) (PαS) cells.
Review on intermediate filaments of the nervous system and their pathological alterations.
Eyer et al., Angers, France. In Histochem Cell Biol, Jul 2013
Intermediate filaments (IFs) of the nervous system, including neurofilaments, α-internexin, glial fibrillary acidic protein, synemin, nestin, peripherin and vimentin, are finely expressed following elaborated cell, tissue and developmental specific patterns.
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.
Cao et al., Baltimore, United States. In Nat Med, Jun 2013
High concentrations of TGF-β1 induced formation of nestin-positive mesenchymal stem cell (MSC) clusters, leading to formation of marrow osteoid islets accompanied by high levels of angiogenesis.
Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.
Kuo et al., Durham, United States. In Nature, Jun 2013
Tamoxifen-inducible nestin-creER(tm)4 lineage tracing demonstrated that it is these SVZ-generated Thbs4(hi) astrocytes, and not Dcx(+) neuroblasts, that home-in on the injured cortex.
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance.
Link et al., Saint Louis, United States. In Nature, Apr 2013
Endosteal osteoblasts and perivascular stromal cells including endothelial cells, CXCL12-abundant reticular cells, leptin-receptor-positive stromal cells, and nestin-green fluorescent protein (GFP)-positive mesenchymal progenitors have all been implicated in HSC maintenance.
What is the clinical value of cancer stem cell markers in gliomas?
Kristensen et al., Odense, Denmark. In Int J Clin Exp Pathol, 2012
Using the Pubmed database, twenty-seven CSC studies looking at membrane markers (CD133, podoplanin, CD15, and A2B5), filament markers (nestin), RNA-binding proteins (Musashi-1) and transcription factors (BMI1, SOX2, Id1 and Oct-4) qualified for this review.
Prognostic impact of nestin expression in resected large cell neuroendocrine carcinoma of the lung.
Masuda et al., Japan. In Lung Cancer, 2012
The present study suggests that nestin expression seems to be a prognostic indicator of a poorer survival probability in patients with resected LCNEC, although its prognostic significance still requires confirmation with larger patient populations.
Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer.
Naito et al., Tokyo, Japan. In Int J Oncol, 2012
Nestin was not localized in the squamous epithelium in normal cervical tissues, but it was weakly expressed in the basal squamous epithelium in cervical intraepithelial neoplasia
Nestin and other putative cancer stem cell markers in pancreatic cancer.
Ishiwata et al., Tokyo, Japan. In Med Mol Morphol, 2012
Studies suggest that nestin may modulate the invasion and metastasis of nestin-positive progenitor cells during pancreatic ductal adenocarcinoma (PDAC) development and may serve as a novel target for suppressing invasion and metastasis in PDAC.
Expression patterns of nestin and dentin sialoprotein during dentinogenesis in mice.
Ohshima et al., Niigata, Japan. In Biomed Res, 2012
Preodontoblasts began to express nestin and Dsp proteins and Dsp mRNA, which increased in their intensity according to the progress of odontoblast differentiation in both incisors and developing molars
Stem cell markers aldehyde dehydrogenase type 1 and nestin expressions in renal cell cancer.
Somay et al., İstanbul, Turkey. In Arch Ital Urol Androl, 2012
Nestin expression was higher in tumor tissues of renal cell carcinoma, than normal tissues (p < 0.05). Nestin expression was inversely related with tumor stage (p < 0.05) but there was no relation with Fuhrman grade.
Astrocytes as neural stem cells in the adult brain.
Quiñones-Hinojosa et al., Colima, Mexico. In J Stem Cells, 2011
In this region resides a subpopulation of astrocytes that express the glial fibrillary acidic protein (GFAP), nestin and carbohydrate Lewis X (LeX).
Detection of cancer stem cell markers in sarcomas.
Neradil et al., Brno, Czech Republic. In Klin Onkol, 2011
Special attention is paid to the detection of CD133, ABC transporters, nestin and aldehyde dehydrogenase that have been intensively studied both in tumour tissues and in sarcoma cell lines during the past few years.
Dopamine Neuron Generation from Human Embryonic Stem Cells.
Park et al., Ch'ŏnan, South Korea. In Int J Stem Cells, 2011
Using this protocol, the majority of differentiated hES cells contained nestin positive cells (>95%) and after final differentiation a high percentage of TuJ1 positive neurons was tyrosine hydroxylase positive (>40%).
More papers using nestin antibodies
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity
Moore Darren J et al., In Molecular Neurodegeneration, 2006
... ] and nestin-Cre [36] transgenic mice were maintained on ...
Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice.
Hatfield Dolph L., In PLoS ONE, 2005
... were crossed with Nestin-Cre transgenic mice ...
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
Morrison Sean J. et al., In Nature, 2002
... Nestin-Cherry transgenic mice ...
Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein.
Borlongan Cesario V., In PLoS ONE, 2001
... Before conducting any experiments, mGFAP-eGFP or nestin-GFP [55] transgenic mice were deeply anesthetized ...
Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide
Condie Brian G. et al., In The Journal of Cell Biology, 2000
... Anti-nestin mouse monoclonal IgG (clone Rat 401) was from BD Biosciences, and monoclonal anti-ceramide mouse ...
Inhibitor of neurite outgrowth in humans.
Cookson Mark R., In PLoS ONE, 1999
... beta and α-tubulin (Sigma); P-STAT3 (Ser727), P-STAT3 (Tyr 705) and STAT3 (CST), P-mTOR and mTOR (CST);Nestin (ABCAM) ; Nogo-A (#Nogo-A 12-A, AD);MBP ...
Live astrocytes visualized by green fluorescent protein in transgenic mice
Bordey Angélique et al., In Frontiers in Neuroscience, 1996
... Neural stem and progenitor cells in nestin-GFP transgenic mice ...
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis.
Callaerts Patrick, In PLoS ONE, 1994
... Louis, MO); mouse monoclonal anti-nestin (Becton Dickinson, Bedford, MA); mouse monoclonal ...
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