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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 May 2015.

Nestin

nestin
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011] (from NCBI)
Top mentioned proteins: CAN, Glial Fibrillary Acidic Protein, Sox2, HAD, vimentin
Papers using nestin antibodies
Dicer1 functions as a haploinsufficient tumor suppressor.
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Reh Thomas A., In PLoS ONE, 2008
... Nestin-Cre transgenic mice ...
The diseasome of physical inactivity–and the role of myokines in muscle–fat cross talk.
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Rota Marcello, In PLoS ONE, 2008
... Nestin-GFP transgenic mice were maintained as ...
Variation in the safety of induced pluripotent stem cell lines.
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Amédée Thierry, In PLoS ONE, 2008
... Nestin-EGFP transgenic mice carry enhanced green ...
NG2 cells generate both oligodendrocytes and gray matter astrocytes
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Kempermann Gerd et al., In Cell and Tissue Research, 2007
... The generation of the Nestin-green fluorescent protein (GFP) transgenic mice was as previously ...
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Papers on nestin
Isolation, in vitro culture and identification of a new type of mesenchymal stem cell derived from fetal bovine lung tissues.
New
Ma et al., Beijing, China. In Mol Med Report, 27 Jun 2015
Following neurogenic differentiation, the cells were morphologically consistent with neuronal cells and positive for microtubule‑associated protein 2 and nestin expression.
Pattern of CXCR7 Gene Expression in Mouse Brain Under Normal and Inflammatory Conditions.
New
Miller et al., Chicago, United States. In J Neuroimmune Pharmacol, 22 Jun 2015
Expression of CXCR7 in the dentate gyrus included cells that expressed nestin, GFAP and cells that appeared to be immature granule cells.
Association of the intermediate filament nestin with cancer stage: a meta-analysis based on 223 positive/high nestin cases and 460 negative/low case-free controls.
New
Chen et al., Zhuhai, China. In Oncotarget, 08 Jun 2015
BACKGROUND: Nestin, a member of the intermediate filament protein family, has been reported to be associated with several types of neoplastic transformation.
Roles and Potential Clinical Applications of Intermediate Filament Proteins in Brain Tumors.
Review
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Skalli et al., Memphis, United States. In Semin Pediatr Neurol, Mar 2015
In addition, brain cancer cells may also contain vimentin, nestin, and synemin, which are the IF proteins found in neural progenitor cells.
Hepatocellular carcinoma may display elevated nestin expression in endothelial cells: experimental study.
New
Teixeira et al., São Paulo, Brazil. In Sao Paulo Med J, Mar 2015
CONTEXT AND OBJECTIVE: Nestin, a class VI intermediate filament protein, is highly expressed in the portal mesenchyme and sinusoidal endothelium of the human fetal liver, but scarcely expressed in adult portal vessel endothelium.
Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system.
Review
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Pekny et al., Utrecht, Netherlands. In Curr Opin Cell Biol, Feb 2015
This coincides with an upregulation and rearrangement of the IFs, which form a highly complex system composed of GFAP (10 isoforms), vimentin, synemin, and nestin.
Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel.
New
Bader et al., Leipzig, Germany. In Drug Des Devel Ther, Dec 2014
The rHuEPO-treated group showed higher expression of stem cell markers (CD 31, CD 90, CD 71, and nestin), which actively contribute to in-wound-healing processes for new hair follicle generation as well as skin regeneration.
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms.
New
Impact
Méndez-Ferrer et al., Madrid, Spain. In Nature, Sep 2014
We previously showed that bone marrow nestin(+) mesenchymal stem cells (MSCs) innervated by sympathetic nerve fibres regulate normal HSCs.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
New
Impact
Lowe et al., New York City, United States. In Cell, Aug 2014
Here, we show that p53 restricts expression of the stem and progenitor-cell-associated protein nestin in an Sp1/3 transcription-factor-dependent manner and that Nestin is required for tumor initiation in vivo.
"Gliomatosis encephali" as a novel category of brain tumors by the first autopsy case report of gliomatosis cerebelli.
Review
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Oyanagi et al., Nagano, Japan. In Neuropathology, Jun 2014
Neuropathological examination identified the tumor cells as being positive for glial fibrillary acidic protein, vimentin and nestin, with atypical nuclei that were cashew-nut- or dishcloth-gourd-shaped.
Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation.
New
Impact
Nagasawa et al., Kyoto, Japan. In Nature, May 2014
Many studies have identified diverse candidate cells that constitute niches for haematopoietic stem cells in the marrow, including osteoblasts, endothelial cells, Schwann cells, α-smooth muscle actin-expressing macrophages and mesenchymal progenitors such as CXC chemokine ligand (CXCL)12-abundant reticular (CAR) cells, stem cell factor-expressing cells, nestin-expressing cells and platelet-derived growth factor receptor-α (PDGFR-α)(+)Sca-1(+)CD45(-)Ter119(-) (PαS) cells.
Direct measurement of local oxygen concentration in the bone marrow of live animals.
New
Impact
Lin et al., Boston, United States. In Nature, May 2014
The endosteal region, by contrast, is less hypoxic as it is perfused with small arteries that are often positive for the marker nestin.
[Bone and Stem Cells. Bone marrow microenvironment niches for hematopoietic stem and progenitor cells].
Review
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Nagasawa, Kyoto, Japan. In Clin Calcium, Apr 2014
The identity and functions of various other candidate HSC niche cells, including nestin-expressing cells and Schwann cells would also be discussed in this review.
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.
Impact
Cao et al., Baltimore, United States. In Nat Med, 2013
High concentrations of TGF-β1 induced formation of nestin-positive mesenchymal stem cell (MSC) clusters, leading to formation of marrow osteoid islets accompanied by high levels of angiogenesis.
Prognostic impact of nestin expression in resected large cell neuroendocrine carcinoma of the lung.
GeneRIF
Masuda et al., Japan. In Lung Cancer, 2012
The present study suggests that nestin expression seems to be a prognostic indicator of a poorer survival probability in patients with resected LCNEC, although its prognostic significance still requires confirmation with larger patient populations.
Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer.
GeneRIF
Naito et al., Tokyo, Japan. In Int J Oncol, 2012
Nestin was not localized in the squamous epithelium in normal cervical tissues, but it was weakly expressed in the basal squamous epithelium in cervical intraepithelial neoplasia
Nestin and other putative cancer stem cell markers in pancreatic cancer.
Review
GeneRIF
Ishiwata et al., Tokyo, Japan. In Med Mol Morphol, 2012
Studies suggest that nestin may modulate the invasion and metastasis of nestin-positive progenitor cells during pancreatic ductal adenocarcinoma (PDAC) development and may serve as a novel target for suppressing invasion and metastasis in PDAC.
Expression patterns of nestin and dentin sialoprotein during dentinogenesis in mice.
GeneRIF
Ohshima et al., Niigata, Japan. In Biomed Res, 2012
Preodontoblasts began to express nestin and Dsp proteins and Dsp mRNA, which increased in their intensity according to the progress of odontoblast differentiation in both incisors and developing molars
Stem cell markers aldehyde dehydrogenase type 1 and nestin expressions in renal cell cancer.
GeneRIF
Somay et al., İstanbul, Turkey. In Arch Ital Urol Androl, 2012
Nestin expression was higher in tumor tissues of renal cell carcinoma, than normal tissues (p < 0.05). Nestin expression was inversely related with tumor stage (p < 0.05) but there was no relation with Fuhrman grade.
Dopamine neuron generation from human embryonic stem cells.
Review
Park et al., Ch'ŏnan, South Korea. In Int J Stem Cells, 2011
Using this protocol, the majority of differentiated hES cells contained nestin positive cells (>95%) and after final differentiation a high percentage of TuJ1 positive neurons was tyrosine hydroxylase positive (>40%).
More papers using nestin antibodies
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity
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Moore Darren J et al., In Molecular Neurodegeneration, 2006
... ] and nestin-Cre [36] transgenic mice were maintained on ...
Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice.
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Hatfield Dolph L., In PLoS ONE, 2005
... were crossed with Nestin-Cre transgenic mice ...
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
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Morrison Sean J. et al., In Nature, 2002
... Nestin-Cherry transgenic mice ...
Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein.
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Borlongan Cesario V., In PLoS ONE, 2001
... Before conducting any experiments, mGFAP-eGFP or nestin-GFP [55] transgenic mice were deeply anesthetized ...
Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide
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Condie Brian G. et al., In The Journal of Cell Biology, 2000
... Anti-nestin mouse monoclonal IgG (clone Rat 401) was from BD Biosciences, and monoclonal anti-ceramide mouse ...
Inhibitor of neurite outgrowth in humans.
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Cookson Mark R., In PLoS ONE, 1999
... beta and α-tubulin (Sigma); P-STAT3 (Ser727), P-STAT3 (Tyr 705) and STAT3 (CST), P-mTOR and mTOR (CST);Nestin (ABCAM) ; Nogo-A (#Nogo-A 12-A, AD);MBP ...
Live astrocytes visualized by green fluorescent protein in transgenic mice
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Bordey Angélique et al., In Frontiers in Neuroscience, 1996
... Neural stem and progenitor cells in nestin-GFP transgenic mice ...
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis.
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Callaerts Patrick, In PLoS ONE, 1994
... Louis, MO); mouse monoclonal anti-nestin (Becton Dickinson, Bedford, MA); mouse monoclonal ...
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