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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 24 Oct 2014.

Nestin

nestin
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011] (from NCBI)
Top mentioned proteins: CAN, Glial Fibrillary Acidic Protein, HAD, Sox2, vimentin
Papers using nestin antibodies
Dicer1 functions as a haploinsufficient tumor suppressor.
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Reh Thomas A., In PLoS ONE, 2008
... Nestin-Cre transgenic mice ...
The diseasome of physical inactivity–and the role of myokines in muscle–fat cross talk.
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Rota Marcello, In PLoS ONE, 2008
... Nestin-GFP transgenic mice were maintained as ...
Variation in the safety of induced pluripotent stem cell lines.
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Amédée Thierry, In PLoS ONE, 2008
... Nestin-EGFP transgenic mice carry enhanced green ...
NG2 cells generate both oligodendrocytes and gray matter astrocytes
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Kempermann Gerd et al., In Cell and Tissue Research, 2007
... The generation of the Nestin-green fluorescent protein (GFP) transgenic mice was as previously ...
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Papers on nestin
Beta cell regeneration after single-round immunological destruction in a mouse model.
New
Ikeda et al., Rochester, United States. In Diabetologia, 23 Nov 2014
This was followed by beta cell mass replenishment, along with enhanced proliferation of insulin-positive cells, recruitment of nestin/CD34-positive endothelial cells, displacement of alpha cells and mobilisation of cytoplasmic neurogenin 3-positive cells.
Differentiation into neurons of rat bone marrow-derived mesenchymal stem cells.
New
Lin et al., Hangzhou, China. In Eur Cytokine Netw, 21 Nov 2014
Cells with processes showed expression of microtubule-associated protein 2 (MAP2) and nestin (NES) as demonstrated by ICC staining, and expression was greater when bFGF and NT-3 were added in combination.
Mapping of potential neurogenic niche in the human temporal lobe.
New
Nogueira, In Arq Neuropsiquiatr, 31 Oct 2014
Neurogenic niches and neurogenesis were investigated in 28 temporal lobes via immunostaining for nestin and doublecortin (DCX), respectively.
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms.
New
Impact
Méndez-Ferrer et al., Madrid, Spain. In Nature, 07 Sep 2014
We previously showed that bone marrow nestin(+) mesenchymal stem cells (MSCs) innervated by sympathetic nerve fibres regulate normal HSCs.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
New
Impact
Lowe et al., New York City, United States. In Cell, Aug 2014
Here, we show that p53 restricts expression of the stem and progenitor-cell-associated protein nestin in an Sp1/3 transcription-factor-dependent manner and that Nestin is required for tumor initiation in vivo.
Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation.
New
Impact
Nagasawa et al., Kyoto, Japan. In Nature, May 2014
Many studies have identified diverse candidate cells that constitute niches for haematopoietic stem cells in the marrow, including osteoblasts, endothelial cells, Schwann cells, α-smooth muscle actin-expressing macrophages and mesenchymal progenitors such as CXC chemokine ligand (CXCL)12-abundant reticular (CAR) cells, stem cell factor-expressing cells, nestin-expressing cells and platelet-derived growth factor receptor-α (PDGFR-α)(+)Sca-1(+)CD45(-)Ter119(-) (PαS) cells.
Direct measurement of local oxygen concentration in the bone marrow of live animals.
New
Impact
Lin et al., Boston, United States. In Nature, May 2014
The endosteal region, by contrast, is less hypoxic as it is perfused with small arteries that are often positive for the marker nestin.
[Bone and Stem Cells. Bone marrow microenvironment niches for hematopoietic stem and progenitor cells].
Review
New
Nagasawa, Kyoto, Japan. In Clin Calcium, Apr 2014
The identity and functions of various other candidate HSC niche cells, including nestin-expressing cells and Schwann cells would also be discussed in this review.
Neuroimmmune interactions of cannabinoids in neurogenesis: focus on interleukin-1β (IL-1β) signalling.
Review
New
Molina-Holgado et al., Toledo, Spain. In Biochem Soc Trans, Dec 2013
NSCs express functional CB1 and CB2 cannabinoid receptors, DAGLα (diacylglycerol lipase α) and the NSC markers SOX-2 and nestin.
Review on intermediate filaments of the nervous system and their pathological alterations.
Review
New
Eyer et al., Angers, France. In Histochem Cell Biol, Jul 2013
Intermediate filaments (IFs) of the nervous system, including neurofilaments, α-internexin, glial fibrillary acidic protein, synemin, nestin, peripherin and vimentin, are finely expressed following elaborated cell, tissue and developmental specific patterns.
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.
New
Impact
Cao et al., Baltimore, United States. In Nat Med, Jun 2013
High concentrations of TGF-β1 induced formation of nestin-positive mesenchymal stem cell (MSC) clusters, leading to formation of marrow osteoid islets accompanied by high levels of angiogenesis.
Neuronal-like differentiation of bone marrow-derived mesenchymal stem cells induced by striatal extracts from a rat model of Parkinson's disease.
Yu et al., Xuzhou, China. In Neural Regen Res, 2013
The results showed that when exposed to lesioned striatal extracts, BMSCs developed bipolar or multi-polar morphologies, and there was an increase in the percentage of cells that expressed glial fibrillary acidic protein (GFAP), nestin and neuron-specific enolase (NSE).
Ipsilateral versus bilateral limb-training in promoting the proliferation and differentiation of endogenous neural stem cells following cerebral infarction in rats.
Cao et al., Shenyang, China. In Neural Regen Res, 2013
The number of nestin/glial fibrillary acidic protein-positive and nestin/microtubule-associated protein 2-positive cells in the peripheral infarct zone and in the corresponding cerebral region in the unaffected hemisphere was significantly higher in rats receiving bilateral limb-training than in rats receiving ipsilateral limb-training.
Prognostic impact of nestin expression in resected large cell neuroendocrine carcinoma of the lung.
GeneRIF
Masuda et al., Japan. In Lung Cancer, 2012
The present study suggests that nestin expression seems to be a prognostic indicator of a poorer survival probability in patients with resected LCNEC, although its prognostic significance still requires confirmation with larger patient populations.
Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer.
GeneRIF
Naito et al., Tokyo, Japan. In Int J Oncol, 2012
Nestin was not localized in the squamous epithelium in normal cervical tissues, but it was weakly expressed in the basal squamous epithelium in cervical intraepithelial neoplasia
Nestin and other putative cancer stem cell markers in pancreatic cancer.
Review
GeneRIF
Ishiwata et al., Tokyo, Japan. In Med Mol Morphol, 2012
Studies suggest that nestin may modulate the invasion and metastasis of nestin-positive progenitor cells during pancreatic ductal adenocarcinoma (PDAC) development and may serve as a novel target for suppressing invasion and metastasis in PDAC.
Expression patterns of nestin and dentin sialoprotein during dentinogenesis in mice.
GeneRIF
Ohshima et al., Niigata, Japan. In Biomed Res, 2012
Preodontoblasts began to express nestin and Dsp proteins and Dsp mRNA, which increased in their intensity according to the progress of odontoblast differentiation in both incisors and developing molars
Stem cell markers aldehyde dehydrogenase type 1 and nestin expressions in renal cell cancer.
GeneRIF
Somay et al., İstanbul, Turkey. In Arch Ital Urol Androl, 2012
Nestin expression was higher in tumor tissues of renal cell carcinoma, than normal tissues (p < 0.05). Nestin expression was inversely related with tumor stage (p < 0.05) but there was no relation with Fuhrman grade.
Astrocytes as neural stem cells in the adult brain.
Review
Quiñones-Hinojosa et al., Colima, Mexico. In J Stem Cells, 2011
In this region resides a subpopulation of astrocytes that express the glial fibrillary acidic protein (GFAP), nestin and carbohydrate Lewis X (LeX).
Dopamine neuron generation from human embryonic stem cells.
Review
Park et al., Ch'ŏnan, South Korea. In Int J Stem Cells, 2011
Using this protocol, the majority of differentiated hES cells contained nestin positive cells (>95%) and after final differentiation a high percentage of TuJ1 positive neurons was tyrosine hydroxylase positive (>40%).
More papers using nestin antibodies
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity
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Moore Darren J et al., In Molecular Neurodegeneration, 2006
... ] and nestin-Cre [36] transgenic mice were maintained on ...
Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice.
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Hatfield Dolph L., In PLoS ONE, 2005
... were crossed with Nestin-Cre transgenic mice ...
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
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Morrison Sean J. et al., In Nature, 2002
... Nestin-Cherry transgenic mice ...
Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein.
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Borlongan Cesario V., In PLoS ONE, 2001
... Before conducting any experiments, mGFAP-eGFP or nestin-GFP [55] transgenic mice were deeply anesthetized ...
Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide
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Condie Brian G. et al., In The Journal of Cell Biology, 2000
... Anti-nestin mouse monoclonal IgG (clone Rat 401) was from BD Biosciences, and monoclonal anti-ceramide mouse ...
Inhibitor of neurite outgrowth in humans.
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Cookson Mark R., In PLoS ONE, 1999
... beta and α-tubulin (Sigma); P-STAT3 (Ser727), P-STAT3 (Tyr 705) and STAT3 (CST), P-mTOR and mTOR (CST);Nestin (ABCAM) ; Nogo-A (#Nogo-A 12-A, AD);MBP ...
Live astrocytes visualized by green fluorescent protein in transgenic mice
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Bordey Angélique et al., In Frontiers in Neuroscience, 1996
... Neural stem and progenitor cells in nestin-GFP transgenic mice ...
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis.
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Callaerts Patrick, In PLoS ONE, 1994
... Louis, MO); mouse monoclonal anti-nestin (Becton Dickinson, Bedford, MA); mouse monoclonal ...
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