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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

NEDL2
Top mentioned proteins: Nedd4, Ubiquitin, p73, Akt, p53
Papers on NEDL2
NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.
New
Zhang et al., Beijing, China. In Cell Signal, Mar 2015
Here, we show that Nedd4-related E3 ubiquitin ligase-2 (NEDL2) plays an essential and positive physiological role in regulating ENS development and GDNF/Ret signaling.
The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.
Zhang et al., Beijing, China. In J Biol Chem, 2014
NEDD4-like ubiquitin ligase 2 (NEDL2) is a HECT type ubiquitin ligase.
A novel HECT-type E3 ubiquitin ligase, NEDL2, stabilizes p73 and enhances its transcriptional activity.
Nakagawara et al., Chiba, Japan. In Biochem Biophys Res Commun, 2003
During the search for interacting molecules with the COOH-terminal proline-rich region of p73, we identified a novel NEDD4-related protein (termed as NEDL2) which contains a C2 domain at its NH(2)-terminus, two WW domains, and a HECT domain at its COOH-terminus.
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