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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 03 Dec 2014.

Neural precursor cell expressed, developmentally down-regulated 1

Top mentioned proteins: gamma-tubulin, GCP, CAN, Plk1, PCM
Papers using NEDD1 antibodies
NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
Merdes Andreas et al., In The Journal of Cell Biology, 2003
... NEDD1 was then subcloned into pEGFPC2 (CLONTECH Laboratories, Inc.) using the ...
FAM29A promotes microtubule amplification via recruitment of the NEDD1–γ-tubulin complex to the mitotic spindle
Fang Guowei et al., In The Journal of Cell Biology, 2000
... The following antibodies were obtained from commercial sources: monoclonal anti-NEDD1 (Abnova Corporation); anti-GFP clone 3E6 ...
Papers on NEDD1
GCP-WD Mediates γ-TuRC Recruitment and the Geometry of Microtubule Nucleation in Interphase Arrays of Arabidopsis.
Ehrhardt et al., Stanford, United States. In Curr Biol, 03 Dec 2014
By imaging the dynamics of individual nucleation events in Arabidopsis, we found that a conserved peripheral protein of the γ-TuRC, GCP-WD/NEDD1 [6-8], associated with motile γ-TuRCs and localized to nucleation events.
Impact of vitrification on the meiotic spindle and components of the microtubule-organizing center in mouse mature oocytes.
Marikawa et al., Honolulu, United States. In Biol Reprod, Nov 2013
Here, to gain insight into the mechanisms of the spindle disappearance and regeneration, we examined the status of spindle microtubules as well as the key components of the microtubule-organizing center (MTOC), specifically gamma-Tubulin, NEDD1, and Pericentrin, in mature (metaphase II) mouse oocytes at different steps of vitrification, a major cryopreservation technique.
Intraperitoneal delivery of a small interfering RNA targeting NEDD1 prolongs the survival of scirrhous gastric cancer model mice.
Sasaki et al., Tokyo, Japan. In Cancer Sci, Feb 2013
The mice treated with small interfering (si) RNA targeting NEDD1, which encodes a gamma-tubulin ring complex-binding protein, by the atelocollagen-mediated delivery system showed a significantly prolonged survival.
The role of NEDD1 phosphorylation by Aurora A in chromosomal microtubule nucleation and spindle function.
Vernos et al., Barcelona, Spain. In Curr Biol, Feb 2013
Here we show that Aurora A interacts with and phosphorylates the γTURC adaptor protein NEDD1 at a single residue, Ser405.
Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair.
Morrison et al., Galway, Ireland. In Plos One, 2012
Interestingly, we found that overexpression of the centrin interactor POC5 leads to the assembly of linear, centrin-dependent structures that recruit other centrosomal proteins such as PCM-1 and NEDD1.
CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly.
Pelletier et al., Toronto, Canada. In Cell Cycle, 2012
We previously reported that CEP192 interacts with NEDD1, a protein that associates with the γ-tubulin ring complex (γ-TuRC) and regulates its phosphorylation status during mitosis.
Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity.
Chen et al., Beijing, China. In Cell Res, 2012
Its interaction with NEDD1 is necessary for the centrosome localization of Cep57.
Nek9 phosphorylation of NEDD1/GCP-WD contributes to Plk1 control of γ-tubulin recruitment to the mitotic centrosome.
Roig et al., Barcelona, Spain. In Curr Biol, 2012
Centrosomal γ-tubulin recruitment depends on the adaptor protein NEDD1/GCP-WD and is controlled by the kinase Plk1.
Novel NEDD1 phosphorylation sites regulate γ-tubulin binding and mitotic spindle assembly.
Pelletier et al., Toronto, Canada. In J Cell Sci, 2012
NEDD1 is a γ-TuRC-interacting protein whose depletion, although not affecting γ-TuRC stability, causes spindle defects similar to the inhibition of its core subunits, including γ-tubulin.
Arabidopsis GCP3-interacting protein 1/MOZART 1 is an integral component of the γ-tubulin-containing microtubule nucleating complex.
Hashimoto et al., Ikoma, Japan. In Plant J, 2012
Functional fusions of GIP1a with green fluorescent protein (GFP) were used to purify GIP1a-containing complexes from Arabidopsis plants, which contained all the subunits (except NEDD1) previously identified in the Arabidopsis γ-tubulin complexes.
Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC.
Raff et al., Oxford, United Kingdom. In Biol Open, 2012
Dgp71WD/Nedd1 proteins are essential for mitotic spindle formation.
PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis.
Rhee et al., Seoul, South Korea. In J Cell Biol, 2012
Phosphoresistant point mutants of PCNT did not recruit centrosomal proteins, such as CEP192, GCP-WD (γ-complex protein with WD repeats), γ-tubulin, Aurora A, and PLK1, into the centrosome during mitosis.
Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1.
Lee et al., Bethesda, United States. In Proc Natl Acad Sci U S A, 2011
Mechanistically, we demonstrated that Cdc2-dependent phosphorylation on a γ-tubulin ring complex (γ-TuRC) recruitment protein, Nedd1/GCP-WD, at the previously uncharacterized S460 residue induces the Nedd1-Plk1 interaction.
NEDD1 is crucial for meiotic spindle stability and accurate chromosome segregation in mammalian oocytes.
Viveiros et al., United States. In Dev Biol, 2010
NEDD1 is an essential component of acentriolar oocyte MTOCs, which functions in the regulation of meiotic spindle stability
A direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome.
Kumar et al., Adelaide, Australia. In Plos One, 2009
a direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome
A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts.
Kumar et al., Adelaide, Australia. In Cell Death Dis, 2009
Disrupting the centrosome in early-passage mouse embryonic fibroblasts by depletion of NEDD1 also resulted in centrosomal fragmentation and subsequent premature entry into senescence.
Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome.
Zhang et al., Beijing, China. In J Cell Sci, 2009
Data suggest that sequential phosphorylation of Nedd1 by Cdk1 and Plk1 plays a role in targeting gamma tubulin ring complex to the centrosome by promoting the interaction of Nedd1 with the gammaTuRC component gamma-tubulin, during mitosis.
The WD40 repeat protein NEDD1 functions in microtubule organization during cell division in Arabidopsis thaliana.
Liu et al., Davis, United States. In Plant Cell, 2009
NEDD1 homolog plays a critical role in MT organization during mitosis.
NEDD1: function in microtubule nucleation, spindle assembly and beyond.
Kumar et al., Adelaide, Australia. In Int J Biochem Cell Biol, 2006
Nedd1 was originally identified as a developmentally regulated gene in the mouse central nervous system.
GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation.
Stearns et al., Stanford, United States. In Nat Cell Biol, 2006
GCP-WD (NEDD1) broadly mediates targeting of the gamma-tubulin ring complex to sites of microtubule nucleation and to the mitotic spindle, which is essential for spindle formation.
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