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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

N-myc downstream regulated 1

NDRG1, RTP, Cap43, Drg1, NDR1
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] (from NCBI)
Papers using NDRG1 antibodies
Functional properties of rab15 effector protein in endocytic recycling.
Supplier
Heisenberg Carl-Philipp, In PLoS ONE, 2004
... For cloning NDRG1 full length gene in a mammalian expression vector NDRG1 was amplified from a prostate cDNA library (Clontech) using reverse primers that ...
Papers on NDRG1
The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
GeneRIF
Richardson et al., Shanghai, China. In J Biol Chem, 2012
chelators inhibit the TGF-beta-induced EMT via a process consistent with NDRG1 up-regulation and elucidates the mechanism of their activity.
NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer.
GeneRIF
Kuwano et al., Kurume, Japan. In J Thorac Oncol, 2012
Loss of NDRG1 is associated with tumor angiogenesis in lung cancer.
Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron.
GeneRIF
Thomas et al., Chicago, United States. In J Biol Chem, 2012
a link between (*)NO, chelatable iron, and regulation of NDRG1 expression and signaling in tumor cells.
The indolic diet-derivative, 3,3'-diindolylmethane, induced apoptosis in human colon cancer cells through upregulation of NDRG1.
GeneRIF
Fares et al., Haifa, Israel. In J Biomed Biotechnol, 2011
Results suggest that N-myc downstream regulated gene-1 expression is enhanced by 3,3'-diindolylmethane in poorly differentiated cells and followed by induction of apoptosis.
Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation.
GeneRIF
Chuang et al., Taipei, Taiwan. In Plos One, 2010
Upon reoxygenation, overexpression of NDRG1 significantly inhibited cell migration
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