Nucleosome positioning in yeasts: methods, maps, and mechanisms.
München, Germany. In Chromosoma, Jun 2015
There is a conserved stereotypical nucleosome organization around transcription start sites (TSSs) with a nucleosome-depleted region (NDR) upstream of the TSS and a TSS-aligned regular array of evenly spaced nucleosomes downstream over the gene body.
Telomere mean length in patients with diabetic retinopathy.
Chandīgarh, India. In Sci Rep, 2014
The study involved 120 subjects, comprising 27 non-insulin dependent diabetes mellitus (NIDDM) without any diabetic retinopathy (NDR), 45 NIDDM subjects with non-proliferative diabetic retinopathy (NPDR), 12 NIDDM subjects with proliferative diabetic retinopathy (PDR) and 36 healthy controls.
Multifaceted roles of Furry proteins in invertebrates and vertebrates.
Sendai, Japan. In J Biochem, 2014
Fry and its orthologues in invertebrates (termed Tao3p in budding yeast, Mor2p in fission yeast, Sax-2 in nematode and Fry in fruit fly) genetically and physically interact with nuclear Dbf2-related (NDR) kinases (termed Cbk1p in budding yeast, Orb6p in fission yeast, Sax-1 in nematode and Trc in fruitfly), and function as activators or scaffolds of these kinases.
AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases.
Frankfurt am Main, Germany. In Biochim Biophys Acta, 2013
The group of AGC protein kinases includes more than 60 protein kinases in the human genome, classified into 14 families: PDK1, AKT/PKB, SGK, PKA, PKG, PKC, PKN/PRK, RSK, NDR, MAST, YANK, DMPK, GRK and SGK494.
The nuts and bolts of AGC protein kinases.
Dundee, United Kingdom. In Nat Rev Mol Cell Biol, 2010
The family comprises some intensely examined protein kinases (such as Akt, S6K, RSK, MSK, PDK1 and GRK) as well as many less well-studied enzymes (such as SGK, NDR, LATS, CRIK, SGK494, PRKX, PRKY and MAST).