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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Nedd4 family interacting protein 2

Top mentioned proteins: Ubiquitin, Nedd4, Ndfip1, Rsp5, Itch
Papers on NDFIP2
Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
Zhang et al., Kingston, Canada. In Biochem J, Dec 2015
In the present study, we demonstrate that Nedd4-2 is directed to specific cellular compartments by the Nedd4 family interacting proteins, Nedd4 family-interacting protein 1 (Ndfip1) and Ndfip2.
13q31.1 microdeletion: A prenatal case report with macrocephaly and macroglossia.
Coutton et al., Grenoble, France. In Eur J Med Genet, Oct 2015
We report on a female fetus with macrocephaly and macroglossia harbouring 13q31.1 microdeletion encompassing three genes: SPRY2, NDFIP2 and RBM26.
Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis.
Kumar et al., Adelaide, Australia. In Blood, 2011
We have previously shown that DMT1 is regulated in vitro by ubiquitination that is facilitated by the adaptor proteins Ndfip1 and Ndfip2.
Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2.
Pelham et al., Cambridge, United Kingdom. In Proc Natl Acad Sci U S A, 2010
PTEN/Akt and MAP kinase signaling pathways are regulated by the ubiquitin ligase activators Ndfip1 and Ndfip2
Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch.
Nishiyama et al., Nagoya, Japan. In Virol J, 2009
Ndfip1 and Ndfip2 were similar in subcellular distribution patterns to UL56 and colocalized with UL56 in co-transfected cells.
Genetic variations in the sodium balance-regulating genes ENaC, NEDD4L, NDFIP2 and USP2 influence blood pressure and hypertension.
Oh et al., Seoul, South Korea. In Kidney Blood Press Res, 2009
The activity of NEDD4L in turn is regulated by phosphorylation by SGK1 and also through interaction with NDFIP2.
Nedd4-interacting protein 2, a short half-life membrane protein degraded in lysosomes, negatively controls down-regulation of connexin43.
Fujita et al., Fukuoka, Japan. In Biol Pharm Bull, 2009
Nedd4-interacting protein 2 (NDFIP2) has three transmembrane domains and interacts with multiple Nedd4 family ubiquitin ligases through polyprolinetyrosine (PY) motifs located in its N-terminal cytoplasmic domain.
Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
Pelham et al., Cambridge, United Kingdom. In Embo Rep, 2009
Data show that the small PY-containing membrane proteins, NDFIP1 and NDFIP2 (NEDD4 family-interacting proteins), activate the catalytic activity of ITCH and of several other HECT ligases by binding to them.
Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.
Kumar et al., Adelaide, Australia. In Blood, 2008
DMT1 interacts with 2 WW domain-interacting proteins, Ndfip1 and Ndfip2. This promotes DMT1 ubiquitination and degradation by WWP2.
Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation.
Lahesmaa et al., Turku, Finland. In J Immunol, 2007
Furthermore, we demonstrate that one of the IL-4 regulated genes, NDFIP2, promotes IFN-gamma production by the polarized human Th1 lymphocytes.
N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking.
Kumar et al., Adelaide, Australia. In J Cell Sci, 2004
N4WBP5A acts as an adaptor to recruit Nedd4 family ubiquitin-protein ligases to the protein trafficking machinery
Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes.
Bierer et al., Bethesda, United States. In J Biol Chem, 2003
N4WBP5A may play a regulatory role in modulating Nedd4 activity at the level of the Golgi apparatus in T lymphocytes
Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein.
Kumar et al., Oxford, United Kingdom. In J Biol Chem, 2002
role in regulating epithelial sodium channel
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