Immunosuppressive drugs, immunophilins, and functional expression of NCX isoforms.
Jerusalem, Israel. In Adv Exp Med Biol, 2012
We have shown that cyclosporin A (CsA) treatment of NCX1-, NCX2-, or NCX3-transfected HEK 293 cells and non-transfected H9c2, L6, and aortic smooth muscle cells, which express NCX1 protein naturally, reduces NCX surface expression and transport activity but has no impact on total cell NCX protein.
Sodium/calcium exchange: its physiological implications.
Baltimore, United States. In Physiol Rev, 1999
Five genes that code for the exchangers have been identified in mammals: three in the Na+/Ca2+ exchanger family (NCX1, NCX2, and NCX3) and two in the Na+/Ca2+ plus K+ family (NCKX1 and NCKX2).