Genetic variation and neuroimaging measures in Alzheimer disease.
Boston, United States. In Arch Neurol, 2010
This study shown that established and candidate AD genes have a role in 6 neuroimaging traits linked to AD. 2 promising genes from Alzheimer disease GWASs, CNTN5 and BIN1, are associated with these neuroimaging measures.
Prolactin regulation of apoptosis-associated gene expression in T cells.
Cincinnati, United States. In Ann N Y Acad Sci, 1999
Experimental results obtained using lactogen-dependent rat pre-T cell lines, the Nb2 lymphoma, have demonstrated that PRL suppresses cell death mechanisms activated by cytokine/hormone deprivation and cytotoxic drugs such as glucocorticoids.
A role for growth hormone and prolactin in leukaemia and lymphoma?
Brussels, Belgium. In Cell Mol Life Sci, 1998
Examples discussed in this review include a rat lymphoma in which the PRL receptor acts as an oncogene; the rat Nb2 lymphoma, which is dependent on PRL for growth; and experiments showing that PRL stimulates natural killer cell activity and the development of lymphokine-activated killer cells.