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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Secretogranin V

N-terminal peptide, C-terminal peptide, 7B2, a C-terminal peptide
Top mentioned proteins: CAN, ACID, fibrillin-1, V1a, HAD
Papers using N-terminal peptide antibodies
A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance
Stow Jennifer L. et al., In The Journal of Cell Biology, 2007
... A rabbit polyclonal antibody raised against a 20–amino acid C-terminal peptide of p110δ was sourced from Abcam ( ...
Papers on N-terminal peptide
Establishment of a normal reference value of parathyroid hormone in a large healthy Chinese population and evaluation of its relation to bone turnover and bone mineral density.
Xia et al., Beijing, China. In Osteoporos Int, Feb 2016
METHODS: Our cross-sectional study included 1436 healthy individuals from 5 different Chinese cities. Concentrations of serum PTH, 25-hydroxyvitamin D (25OHD), procollagen I N-terminal peptide (P1NP, a bone formation marker), and carboxyl-terminal telopeptide of type I collagen (β-CTX, a bone resorption marker) were measured by electrochemiluminescence immunoassay.
The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1.
Wittung-Stafshede et al., Umeå, Sweden. In Biophys J, Feb 2016
The C-terminal peptide and Atox1 do not interact in solution in the absence of Cu.
A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation.
Curry et al., London, United Kingdom. In Plos Pathog, Jan 2016
The functional significance of the VPg-eIF4G interaction was shown by the ability of fusion proteins containing the C-terminal peptide of MNV VPg to inhibit in vitro translation of norovirus RNA but not cap- or IRES-dependent translation.
Circulating Procollagen Type III N-Terminal Peptide and Mortality Risk in African Americans with Heart Failure.
Cavallari et al., Chicago, United States. In J Card Fail, Jan 2016
BACKGROUND: Procollagen type III N-terminal peptide (PIIINP) is a biomarker of cardiac fibrosis that is associated with heart failure prognosis in Caucasians.
The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Mandel et al., Portland, United States. In Elife, Dec 2015
A previous line of mice deleted for REST in progenitors by conventional gene targeting does not exhibit these phenotypes, likely due to a remaining C-terminal peptide that still binds chromatin and recruits co-repressors.
Tribbles pseudokinases: novel targets for chemical biology and drug discovery?
Eyers et al., Liverpool, United Kingdom. In Biochem Soc Trans, Nov 2015
The three human TRIB family members are uniquely defined by an acidic pseudokinase domain containing a 'broken' α C-helix and a MEK (MAPK/ERK)-binding site at the end of the putative C-lobe and a distinct C-terminal peptide motif that interacts directly with a small subset of cellular E3 ubiquitin ligases.
The Origin, Expression, Function and Future Research Focus of a G Protein-coupled Receptor, Mas-related Gene X2 (MrgX2).
Sha et al., Shenzhen, China. In Prog Histochem Cytochem, Jul 2015
It can interact with a series of factors and genes such as the peptides substance P, vasoactive intestinal peptide, cortistatin (CST), proadrenomedullin N-terminal peptide (PAMP), LL-37, PMX-53 and β-defensins.
Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome.
van Hall et al., Leiden, Netherlands. In Front Immunol, 2014
An exception is the C-terminal peptide of the endoplasmic reticulum (ER)-membrane-spanning ceramide synthase Trh4 that is surprisingly liberated by the signal peptide peptidase (SPP), the proteolytic enzyme involved in cleaving leader sequences.
De novo discovery of bioactive cyclic peptides using bacterial display and flow cytometry.
Daugherty et al., Santa Barbara, United States. In Methods Mol Biol, 2014
Due to their limited conformational flexibility, cyclic peptides with C-to-N-terminal peptide bond and a disulfide bridge can confer high target binding affinity and resistance to proteolytic enzymes.
Somatic mutations of calreticulin in myeloproliferative neoplasms.
Kralovics et al., Pavia, Italy. In N Engl J Med, 2014
A total of 36 types of insertions or deletions were identified that all cause a frameshift to the same alternative reading frame and generate a novel C-terminal peptide in the mutant calreticulin.
Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells.
Kos et al., Ljubljana, Slovenia. In Front Immunol, 2013
After proteolytic removal of its N-terminal peptide, cystatin F becomes a potent inhibitor of cathepsin C with the potential to regulate pro-granzyme processing and cell cytotoxicity.
Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.
Waha et al., Bonn, Germany. In Int J Cancer, 2012
the significant effects of SGNE1/7B2 on the growth and apoptosis of glioblastoma cells provide a first proof for a functional implication of SGNE1/7B2 inactivation in the molecular pathology of gliomas.
The extended granin family: structure, function, and biomedical implications.
Salton et al., Minneapolis, United States. In Endocr Rev, 2011
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) that together comprise the granin family subserve essential roles in the regulated secretory pathway that is responsible for controlled delivery of peptides, hormones, neurotransmitters, and growth factors.
HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide.
Wucherpfennig et al., Boston, United States. In Nat Immunol, 2011
Nonbinding covalent HLA-DR-peptide complexes were converted into efficient HLA-DM binders after truncation of an N-terminal peptide segment that emptied the P1 pocket and disrupted conserved hydrogen bonds to HLA-DR.
Regulation of 7B2 mRNA translation: dissecting the role of its 5'-untranslated region.
Mbikay et al., Ottawa, Canada. In Methods Mol Biol, 2010
Acute exposure of MIN6 cells transduced with rat 7B2 to high glucose increased endogenous 7B2 biosynthesis without affecting the levels of its mRNA.
Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10.
Lifton et al., New Haven, United States. In Science, 2010
This allowed us to map and identify disease-causing mutations in the gene encoding keratin 10 (KRT10); all result in frameshifts into the same alternative reading frame, producing an arginine-rich C-terminal peptide that redirects keratin 10 from the cytokeratin filament network to the nucleolus.
Measurements of secretogranins II, III, V and proconvertases 1/3 and 2 in plasma from patients with neuroendocrine tumours.
Janson et al., Uppsala, Sweden. In Regul Pept, 2008
Secretogranins V assays failed to detect increased concentrations in any of the patients with neuroendocrine tumours.
SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.
Waha et al., Bonn, Germany. In Oncogene, 2007
SGNE1 identified as a novel epigenetically silenced gene in medulloblastomas and its inactivation, as well as its inhibitory effect on tumor cell proliferation and focus formation strongly argues for a significant role in medulloblastoma development.
Structure and function of RbcX, an assembly chaperone for hexadecameric Rubisco.
Hayer-Hartl et al., Martinsried, Germany. In Cell, 2007
A central cleft specifically binds the exposed C-terminal peptide of RbcL subunits, enabling a peripheral surface of RbcX to mediate RbcL(8) assembly.
Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.
Meyre et al., Lille, France. In Bmc Med Genet, 2006
SGNE1 genetic variation does not contribute to obesity and common forms of Type 2 diabetes but may worsen glucose intolerance and insulin resistance, especially in the background of severe and early onset obesity
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