Blood-testis barrier and Sertoli cell function: lessons from SCCx43KO mice.
Hannover, Germany. In Reproduction, Feb 2016
Although the SC specific KO of CX43 does not seem to have an adverse effect on BTB integrity, CX43 influences BTB composition as the expression pattern of different BTB proteins (like OCCLUDIN, β-CATENIN, N-CADHERIN, and CLAUDIN11) is altered in mutant males.
Rab, Arf and Arl-Regulated Membrane Traffic in Cortical Neuron Migration.
Singapore, Singapore. In J Cell Physiol, Dec 2015
Rab5 and Rab11, which are key modulators of endocytosis and endocytic recycling respectively, ensure proper surface expression and distribution of N-cadherin, a key adhesion protein that tethers migrating neurons to the radial glia fiber tracts during pia-directed migration.
Retrograde flow of cadherins in collective cell migration.
London, United Kingdom. In Nat Cell Biol, 2014
The maintenance of N-cadherin-based junctions during collective migration is now shown to be facilitated by their treadmilling from the cell front to the rear, followed by N-cadherin endocytosis and recycling to the leading edge.
Neural stem cell quiescence comes to an un-sticky end.
More papers using
Edinburgh, United Kingdom. In Nat Cell Biol, 2014
N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.
In PLoS ONE, 2002
... (M2), anti-actin, anti-nucleolin from Sigma-Aldrich (St Louis, MO), anti-E-cadherin from BD Biosciences (San Diego, CA), anti-N-cadherin from Epitomics (Burlingame, CA), anti-Snail (ab85931), ...