Study on the anaphylactoid of three phenolic acids in Honeysuckle.
Nanjing, China. In J Ethnopharmacol, 12 Jun 2015
In vitro and in vivo studies showed that CA and CCA could significantly increase the plasma serotonin and β-hexosaminidase levels in guinea pigs and induce the degranulation of RBL-2H3 cell, while NCA did not show such properties.
Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.
Philadelphia, United States. In Nat Med, 2013
We now report that conditional deletion or pharmacologic inhibition of one HAT, p300 (also known as Ep300 or KAT3B), in Foxp3(+) T(reg) cells increased T cell receptor-induced apoptosis in T(reg) cells, impaired T(reg) cell suppressive function and peripheral T(reg) cell induction, and limited tumor growth in immunocompetent but not in immunodeficient mice.
Anion-π interactions in supramolecular architectures.
College Station, United States. In Acc Chem Res, 2013
Finally, we explored the reactions of the extended π-acidic heterocycle HAT(CN)6 (1,4,5,8,9,12-hexaazatriphenylene-hexacarbonitrile) with the Cl(-), Br(-), I(-) ions which lead to highly colored solutions/crystals.