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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Protein phosphatase 1, regulatory subunit 16A

Top mentioned proteins: CAN, PP1, V1a, ACID, Actin
Papers on MYPT3
Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.
Scholz et al., Leipzig, Germany. In Plos Genet, Sep 2015
Based on an integrative analysis of expression quantitative trait loci in blood mononuclear cells and correlations between gene expressions and metabolite levels, we provide evidence for putative causative genes: SLC22A16 for total acylcarnitines, ARG1 for arginine, HLCS for 2-hydroxyisovalerylcarnitine, JAM3 for stearoylcarnitine via a trans-effect at chromosome 1, and PPP1R16A for aspartic acid traits.
Amplification of chromosome 8q21-qter associated with the acquired paclitaxel resistance of nasopharyngeal caricinoma cells.
Tan et al., Changsha, China. In Int J Clin Exp Pathol, 2014
15 genes of 762 transcripts on this chromosome region were consistently up-regulated detected by cDNA microarray in three taxol resistant sub-lines, and functionally clustered into various groups, including genes related to vascular formation vascular formation (ANGPT1), apoptosis (MYC, TOP1MT), cell adhesion and cell cycle (PPP1R16A, SDC2, CA2, ANKRD46), gene regulation (HRSP12, ZNF696, SLC39A4, POP1), metabolism (PYCRL).
Molecular markers of endometrial carcinoma detected in uterine aspirates.
Gil-Moreno et al., Barcelona, Spain. In Int J Cancer, 2011
We identified ACAA1, AP1M2, CGN, DDR1, EPS8L2, FASTKD1, GMIP, IKBKE, P2RX4, P4HB, PHKG2, PPFIBP2, PPP1R16A, RASSF7, RNF183, SIRT6, TJP3, EFEMP2, SOCS2 and DCN as differentially expressed in ECs.
Ornithine decarboxylase antizyme Oaz3 modulates protein phosphatase activity.
van der Hoorn et al., Calgary, Canada. In J Biol Chem, 2011
We identified myosin phosphatase targeting subunit 3 (MYPT3), a regulator of protein phosphatase PP1β, as a major p12-interacting protein, and show that MYPT3 is present in sperm tails and that its ankyrin repeat binds p12.
The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ.
MacDonald et al., Calgary, Canada. In Arch Biochem Biophys, 2011
The mammalian MYPT family consists of the products of five genes, denoted MYPT1, MYPT2, MBS85, MYPT3 and TIMAP, which function as targeting and regulatory subunits to confer substrate specificity and subcellular localization on the catalytic subunit of type 1δ protein serine/threonine phosphatase (PP1cδ).
Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.
Demiryurek et al., Gaziantep, Turkey. In Endocr Pathol, 2011
PPP1R16A gene expression is decreased in follicular variant of papillary thyroid carcinoma.
PPP1R16A, the membrane subunit of protein phosphatase 1beta, signals nuclear translocation of the nuclear receptor constitutive active/androstane receptor.
Negishi et al., United States. In Mol Pharmacol, 2008
R16A at the membrane may mediate the PB signal to initiate CAR nuclear translocation, through a mechanism including its dimerization and inhibition of PP1beta activity.
Phosphorylation of myosin phosphatase targeting subunit 3 (MYPT3) and regulation of protein phosphatase 1 by protein kinase A.
Leung et al., Singapore, Singapore. In J Biol Chem, 2006
analysis of a novel mechanism for the phosphorylation of MYPT3 by PKA and activation of the catalytic activity through direct interaction of a central region of MYPT3 with its N-terminal region
The essential role of PP1beta in Drosophila is to regulate nonmuscle myosin.
Alphey et al., Oxford, United Kingdom. In Mol Biol Cell, 2004
Drosophila has two nonmuscle myosin targeting subunits, one of which (MYPT-75D) resembles MYPT3, binds specifically to PP1beta, and activates PP1beta's Sqh phosphatase activity.
Myosin phosphatase: structure, regulation and function.
Hartshorne et al., Tsu, Japan. In Mol Cell Biochem, 2004
A recent discovery is the existence of an MYPT family and members include, MYPT1, MYPT2, MBS85, MYPT3 and TIMAP.
TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells.
Ballermann et al., Baltimore, United States. In Am J Physiol Cell Physiol, 2002
The TIMAP protein contains five ankyrin repeats, a protein phosphatase-1 (PP1)-interacting domain, a COOH-terminal CAAX box, a domain arrangement similar to that of MYPT3, and a PP1 inhibitor.
Cloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1.
Saltiel et al., Ann Arbor, United States. In Biochem J, 2001
In the present work, the isolation, identification and initial biochemical characterization of a novel PP1-interacting protein, MYPT3, which is homologous with the myosin phosphatase targetting subunit (MYPT) family, is described.
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