[Reprogramming of somatic cells. Problems and solutions].
In Tsitologiia, 2013
The possibility of direct conversion of one differentiated cell type to another was first shown in the 80s of the last century in experiments on the conversion of fibroblasts into myoblasts by ectopic expression of the transcription factor MyoD. Surprisingly, this technology has remained unclaimed in cell biology for a long time.
Molecular and cellular regulation of skeletal myogenesis.
Paris, France. In Curr Top Dev Biol, 2013
Since the seminal discovery of the cell-fate regulator Myod, studies in skeletal myogenesis have inspired the search for cell-fate regulators of similar potential in other tissues and organs.
Finding MyoD with a little help from my friends.
Boston, United States. In Nat Cell Biol, 2012
Findings indicate that MyoD activates the expression of other muscle regulators such as MEF2 and myogenin, which are necessary for induction of the skeletal muscle differentiation program.