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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 Mar 2014.

Myogenic differentiation 1

MyoD, MyoD1
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Myogenin, CAN, Myf5, PAX7, HAD
Papers using MyoD antibodies
A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss
Supplier
Dhar M. S. et al., In Journal of Nutrition and Metabolism, 2010
... MyoD and Atp10c were from Qiagen (Valencia, CA) ...
Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice.
Supplier
Agarwal Sudha, In PLoS ONE, 2009
... , and MyoD-hBcl-2 transgenic mice that overexpress human ...
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
Supplier
Chen Jie et al., In The Journal of Cell Biology, 2006
... The antibodies were obtained from the following sources: anti-tubulin was obtained from Abcam, anti-MyoD (5.8A) was obtained from Imgenex, antibodies against HDAC4, mTOR, ...
Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population
Supplier
Simon András et al., In The Journal of Cell Biology, 2003
... Invitrogen), rabbit polyclonal anti-H3P antibody (Upstate Biotechnology), rat monoclonal anti-BrdU IgG (Trichem ApS), rabbit polyclonal anti-MyoD antibody (Santa Cruz Biotechnology, Inc.), anti-WE3 monoclonal IgG ...
The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure
Supplier
Martins-Green Manuela et al., In The Journal of Cell Biology, 1998
... used were: anti–α-SMA (Sigma-Aldrich); anti-TGFβ 1,2,3 (R&D Systems); antivimentin, antidesmin, antimyosin heavy chain (Hybridoma Bank); anti-myoD (Santa Cruz Biotechnology, Inc.); anti–mouse horseradish peroxidase, ...
Papers on MyoD
Chronic binge alcohol consumption alters myogenic gene expression and reduces in vitro myogenic differentiation potential of myoblasts from rhesus macaques.
New
Molina et al., New Orleans, United States. In Am J Physiol Regul Integr Comp Physiol, 26 Apr 2014
Myoblasts from the CBA group had significantly reduced PAX7 MYOD1, myogenin, MYF5 and MEF2C expression.
Regenerative defect in vastus lateralis muscle of patients with chronic obstructive pulmonary disease.
New
Debigaré et al., In Respir Res, 25 Apr 2014
In muscle homogenates, increased expression of MyoD and decreased expression of myogenin and MRF4 were observed in COPD.
Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.
New
Kataoka et al., Tokyo, Japan. In J Control Release, 19 Apr 2014
To rescue the skeletal muscle and promote functional recovery, insulin-like growth factor-1 (IGF-1), a potent myogenic factor, was introduced into the muscle by hydrodynamic injection of IGF-1-expressing plasmid DNA using a biocompatible nonviral gene carrier, a polyplex nanomicelle.
Gene Regulatory Networks and Transcriptional Mechanisms that Control Myogenesis.
Review
New
Rigby et al., Paris, France. In Dev Cell, 10 Mar 2014
Myogenic determination and subsequent differentiation depend on members of the MyoD family.
Patterns of positive selection of the myogenic regulatory factor gene family in vertebrates.
New
Liu et al., Tai'an, China. In Plos One, Dec 2013
Here, we show that sites under positive selection were more frequently detected and identified from the genes encoding the myogenic differentiation factors (MyoG and Myf6) than the genes encoding myogenic determination factors (Myf5 and MyoD).
Identification of Genes Differentially Expressed in Myogenin Knock-Down Bovine Muscle Satellite Cells during Differentiation through RNA Sequencing Analysis.
New
Choi et al., Kyŏngsan, South Korea. In Plos One, Dec 2013
BACKGROUND: The expression of myogenic regulatory factors (MRFs) consisting of MyoD, Myf5, myogenin (MyoG) and MRF4 characterizes various phases of skeletal muscle development including myoblast proliferation, cell-cycle exit, cell fusion and the maturation of myotubes to form myofibers.
Skeletal muscle hypertrophy and regeneration: interplay between the myogenic regulatory factors (MRFs) and insulin-like growth factors (IGFs) pathways.
Review
New
Gailly et al., Brussels, Belgium. In Cell Mol Life Sci, Nov 2013
In response to stimuli such as injury or exercise, these cells become activated and express myogenic regulatory factors (MRFs), i.e., transcription factors of the myogenic lineage including Myf5, MyoD, myogenin, and Mrf4 to proliferate and differentiate into myofibers.
Mechanisms of impaired differentiation in rhabdomyosarcoma.
Review
New
Guttridge et al., Portland, United States. In Febs J, Sep 2013
Both eRMS and aRMS tumor cells express myogenic markers such as MyoD, but their ability to complete differentiation is impaired.
Dial M(RF) for myogenesis.
Review
New
Carvajal et al., London, United Kingdom. In Febs J, Sep 2013
The transcriptional regulatory network that controls the determination and differentiation of skeletal muscle cells in the embryo has at its core the four myogenic regulatory factors (MRFs) Myf5, MyoD, Mrf4 and MyoG.
Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis.
Review
New
Nodit et al., Knoxville, United States. In Arch Pathol Lab Med, Aug 2013
Immunohistochemical workup demonstrates sarcomeric differentiation with reactivity for desmin, myogenin, and MyoD1 markers.
Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38α/β MAPK.
Impact
Olwin et al., Boulder, United States. In Cell Stem Cell, 2012
Asymmetric localization of the Par complex activates p38α/β MAPK in only one daughter cell, inducing MyoD, which permits cell cycle entry and generates a proliferating myoblast.
Interplay between two myogenesis-related proteins: TBP-interacting protein 120B and MyoD.
GeneRIF
Tamura et al., Chiba, Japan. In Gene, 2012
results suggest that MyoD and TIP120B potentiate each other at gene expression and post-translation levels, respectively, which may promote myogenesis cooperatively
Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis.
GeneRIF
Rudnicki et al., Ottawa, Canada. In Mol Cell, 2012
In primary myoblasts, snail-HDAC1/2 repressive complex binds and excludes MyoD from its targets.
Myo/Nog cells in normal, wounded and tumor-bearing skin.
GeneRIF
George-Weinstein et al., In Exp Dermatol, 2012
Myo/Nog cells are the primary source of noggin in telogen hair follicles.
Muscle function and running activity in mouse models of hereditary muscle dystrophy: impact of double knockout for dystrophin and the transcription factor MyoD.
GeneRIF
Gielen et al., Leipzig, Germany. In Muscle Nerve, 2012
mdx:myoD(-/-) is not a suitable model to study exercise-induced effects on dystrophic muscles
Finding MyoD with a little help from my friends.
Impact
GeneRIF
Lassar, Boston, United States. In Nat Cell Biol, 2012
Findings indicate that MyoD activates the expression of other muscle regulators such as MEF2 and myogenin, which are necessary for induction of the skeletal muscle differentiation program.
Polycomb-repressed genes have permissive enhancers that initiate reprogramming.
Impact
GeneRIF
Jones et al., Los Angeles, United States. In Cell, 2012
Using MYOD1, study shows that an nucleosome-depleted region at the minimal enhancer region allows reprogramming to be initiated, which occurs in response to signals such as the forced expression of Myod1 in fibroblasts.
Cell fate plug and play: direct reprogramming and induced pluripotency.
Review
Impact
Studer et al., New York City, United States. In Cell, 2011
Building on the discovery that MyoD expression reprograms fibroblasts into muscle, three papers (Vierbuchen et al., 2010; Ieda et al., 2010; Szabo et al., 2010) recently reported the reprogramming of fibroblasts into neurons, cardiomyocytes, and blood cell progenitors without first passing the cells through a pluripotent state.
Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation.
Impact
Eisenman et al., Seattle, United States. In Cell, 2010
Ectopic expression of Myc-nick accelerates myoblast fusion, triggers the expression of myogenic markers, and permits Myc-deficient fibroblasts to transdifferentiate in response to MyoD.
Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription.
Impact
Gurdon et al., Cambridge, United Kingdom. In Nat Cell Biol, 2008
We find that memory can persist through 24 cell divisions in the absence of transcription and applies to the expression of the myogenic gene MyoD in non-muscle cell lineages of nuclear transplant embryos.
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