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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Myosin IIIB

Myo3B
Top mentioned proteins: MYO3A, Actin, Espin, V1a, erbB-3
Papers on Myo3B
Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal.
Oliveira et al., Lisbon, Portugal. In Plos One, 2014
rs4667622 (between UBR3 and MYO3B), rs6599001 (between SCN11A and WDR48), rs3932338 (214 kilobases downstream of PRDM9), and rs10943471 (96 kilobases upstream of HTR1B) were associated with IA (unadjusted allelic chi-square tests) in the datasets tested (discovery: 6.84E-04≤P≤1.92E-02,
Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins.
O'Tousa et al., Richmond, United States. In Plos One, 2014
In COS7 cells, MORN4 and MYO3A, but not MORN4 and MYO3B, co-localize to actin rich filopodia extensions.
Genome-Wide Association Identifies SLC2A9 and NLN Gene Regions as Associated with Entropion in Domestic Sheep.
White et al., Pullman, United States. In Plos One, 2014
Six additional genome-wide suggestive SNP (nominal P<1x10(-5)) were identified including markers in or near PIK3CB (P = 2.22x10(-6); additive model), KCNB1 (P = 2.93x10(-6); dominance model), ZC3H12C (P = 3.25x10(-6); genotypic model), JPH1 (P = 4.68x20(-6); genotypic model), and MYO3B (P = 5.74x10(-6); recessive model).
Genome-wide association study identifies novel loci associated with resistance to bovine tuberculosis.
Glass et al., Belfast, United Kingdom. In Heredity (edinb), 2014
Genome-wide rapid association using linear and logistic mixed models and regression (GRAMMAR), regional heritability mapping (RHM) and haplotype-sharing analysis identified two novel resistance loci that attained chromosome-wise significance, protein tyrosine phosphatase receptor T (PTPRT; P=4.8 × 10(-7)) and myosin IIIB (MYO3B; P=5.4 × 10(-6)).
Kinome-wide screening of HER2+ breast cancer cells for molecules that mediate cell proliferation or sensitize cells to trastuzumab therapy.
Mak et al., Toronto, Canada. In Oncogenesis, 2013
Antagonism using the SI identified MYO3A, MYO3B and MPZL1 as antagonizers to trastuzumab treatment among HER2+ cell lines.
A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of urinary symptoms after radiotherapy for prostate cancer.
Rosenstein et al., New York City, United States. In J Urol, 2013
Several of these single nucleotide polymorphisms were more strongly associated with change in specific AUA Symptom Score items, including rs13035033 in the MYO3B gene, which was associated with straining (beta coefficient 0.9, 95% CI 0.6-1.2,
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.
GeneRIF
Kachar et al., Bethesda, United States. In Curr Biol, 2012
When myosin IIIB (MYO3B) is coexpressed with espin-1 (ESPN1), MYO3B targets and carries ESPN1 to COS7 cell filopodia tips. This tip localization is lost when the ESPN1 C terminus actin-binding site is removed.
Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.
Battelle et al., United States. In Exp Eye Res, 2009
Although vertebrates possess two class III myosin genes, myo3A and myo3B, recent studies have focused on Myo3A because mutations in the human gene are implicated in progressive hearing loss.
Myo3A, one of two class III myosin genes expressed in vertebrate retina, is localized to the calycal processes of rod and cone photoreceptors and is expressed in the sacculus.
Burnside et al., Berkeley, United States. In Mol Biol Cell, 2003
We report the cloning, sequence analysis, and expression patterns of the long (Myo3A) and short (Myo3B) class III myosins, as well as cellular localization and biochemical characterization of the long isoform, Myo3A.
A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome.
Burnside et al., Berkeley, United States. In Genomics, 2002
Here we introduce a shorter class III myosin isoform, MYO3B, which is expressed in the retina, kidney, and testis.
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