Regulation of human subcutaneous adipocyte differentiation by EID1.
Maebashi, Japan. In J Mol Endocrinol, Feb 2016
Transfection of EID1 into ADMSCs reduced triglyceride accumulation while increasing levels of thermogenic proteins, such as PGC1α, TFAM, and mitochondrial uncoupling protein 1 (UCP1), all of which are markers of energy expenditure and mitochondrial activity.
Brown adipose tissue thermogenesis in humans.
Turku, Finland. In Diabetologia, 2013
In contrast to white adipocytes, which store energy, brown adipocytes generate heat via mitochondrial uncoupling protein 1, thereby acting as a defence against hypothermia and, potentially, obesity.
A new look at UCP 1.
Dublin, Ireland. In Biochim Biophys Acta, 2006
There has been a resurgence of interest in mitochondrial uncoupling protein 1 due to a desire to understand the regulation of the prominent role it plays in control of metabolic flux in brown adipose tissue and non-shivering thermogenesis, combined with the fact that UCP 1 acts as a paradigm for other novel less abundant uncoupling proteins.
Amish Lethal Microcephaly
Seattle, United States. In Unknown Journal, 2003
SLC25A19 (also known as DNC or MUP1) is the only gene known to be associated with Amish lethal microcephaly.