A meta-analysis of gene expression signatures of blood pressure and hypertension.
Bethesda, United States. In Plos Genet, Mar 2015
Of note, rs3184504 in SH2B3, which was also reported in GWAS to be associated with BP, was found to be a trans regulator of the expression of 6 of the transcripts we found to be associated with BP (FOS, MYADM, PP1R15A, TAGAP, S100A10, and FGBP2).
The enigmatic thymine DNA glycosylase.
Basel, Switzerland. In Dna Repair (amst), 2007
TDG turned out to be the founding member of a newly emerging family of mismatch-directed uracil-DNA glycosylases, the MUG proteins, that act on a comparably broad spectrum of base lesion including G.U as the common, most efficiently processed substrate.