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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Mucin 13, cell surface associated

Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008] (from NCBI)
Top mentioned proteins: MUC4, MUC2, MUC5AC, MUC1, MUC6
Papers on MUC13
Possible prediction of the response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy based on gene expression profiling.
Chen et al., Beijing, China. In Oncotarget, Jan 2016
IHC was conducted to examine the expression of selected target markers MUC4, MUC13, and MUC20 in 186 ESCC resection samples and the relationships between their expression and tumor regression grade was analyzed.
Lawsonia intracellularis infection of intestinal crypt cells is associated with specific depletion of secreted MUC2 in goblet cells.
Ait-Ali et al., Edinburgh, United Kingdom. In Vet Immunol Immunopathol, Dec 2015
The expression patterns of secreted (MUC2 and MUC5AC) and membrane-tethered (MUC1, MUC4, MUC12 and MUC13) mucins were monitored in healthy pigs and pigs challenged orally with Lawsonia intracellularis.
The expression and prognostic significance of Mucin 13 and Mucin 20 in esophageal squamous cell carcinoma.
Chen et al., Beijing, China. In J Cancer Res Ther, Aug 2015
BACKGROUND: Mucin 13 (MUC13) and Mucin 20 (MUC20) are high molecular weight transmembrane O-linked glycoprotein secreted by epithelium and are widely overexpressed in epithelial tumor cells.
Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects.
and the Nephrotic Syndrome Study Network et al., Los Angeles, United States. In J Am Soc Nephrol, Aug 2015
Differential expression analysis demonstrated an increased steady-state level of five genes associated with the high-risk genotype (CXCL9, CXCL11, and UBD in glomerulus; SNOR14B and MUC13 in tubulointerstitium).
New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression.
Roxo-Rosa et al., Rio de Mouro, Portugal. In World J Gastroenterol, Jul 2015
Both clones were shown to produce high amounts of MUC1, MUC2 and MUC13.
A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells.
Sakuma et al., Sapporo, Japan. In Int J Oncol, Apr 2015
The mAb, designated TCC56, recognized Mucin 13 (MUC13), while TCC56‑DT3C conjugates induced cell death in TCC-PAN2 cells expressing MUC13.
MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer.
Chauhan et al., Memphis, United States. In Oncotarget, 2014
MUC13, a transmembrane mucin is highly involved in pancreatic cancer progression.
Mucin gene mRNA levels in broilers challenged with eimeria and/or Clostridium perfringens.
Hughes et al., In Avian Dis, 2014
The effects of Eimeria (EM) and Clostridium perfringens (CP) challenges on the mRNA levels of genes involved in mucin (Muc) synthesis (Muc2, Muc5ac, Muc13, and trefoil family factor-2 [TFF2]), inflammation (tumor necrosis factor alpha [TNF-alpha] and interleukin-18 [IL-18]), and metabolic processes (cluster of differentiation [CD]36) in the jejunum of broilers were investigated.
Overexpression of mucin 13 due to promoter methylation promotes aggressive behavior in ovarian cancer cells.
Ahn et al., Seoul, South Korea. In Yonsei Med J, 2014
To address epigenetically-regulated gene products involved in ovarian cancer metastasis, we examined the mechanisms regulating mucin 13 (MUC13) expression and its influence on aggressive behaviors of ovarian malignancies.
Enteric mucosa integrity in the presence of a preserved innate interleukin 22 compartment in HIV type 1-treated individuals.
Sousa et al., Setúbal, Portugal. In J Infect Dis, 2014
Remarkably, levels of transcripts of IL-22-target genes (ie, REG3G, DEFB4A, S100A9, MUC1, and MUC13) were unaltered, suggesting an adequate production of antimicrobial peptides and mucins.
Gastric de novo Muc13 expression and spasmolytic polypeptide-expressing metaplasia during Helicobacter heilmannii infection.
Haesebrouck et al., Merelbeke, Belgium. In Infect Immun, 2014
Interestingly, Muc13 was upregulated already at 1 day postinfection in the fundus of the stomach.
Refined candidate region for F4ab/ac enterotoxigenic Escherichia coli susceptibility situated proximal to MUC13 in pigs.
Peelman et al., Gent, Belgium. In Plos One, 2013
Based on the predicted differential O-glycosylation patterns of the 2 MUC13 variants (MUC13A and MUC13B) in F4ac ETEC susceptible and F4ac ETEC resistant pigs, the MUC13 gene was recently proposed as the causal gene for F4ac ETEC susceptibility.
MUC13 mucin augments pancreatic tumorigenesis.
Jaggi et al., Sioux Falls, United States. In Mol Cancer Ther, 2012
MUC13 overexpression caused a significant increase in cell motility, invasion, proliferation, and anchorage-dependent or -independent clonogenicity while decreasing cell-cell and cell-substratum adhesion in pancreatic cancer.
The search for the gene mutations underlying enterotoxigenic Escherichia coli F4ab/ac susceptibility in pigs: a review.
Buys et al., Leuven, Belgium. In Vet Res, 2011
Numerous SNP analyses and a few expression studies on the three MUC-genes (MUC4, MUC13 and MUC20) and the transferrin receptor gene (TFRC) as well as on some other positional candidate genes have been performed in order to find the causative mutation for the ETEC-F4ab/ac receptor(s).
Mucin 13: structure, function, and potential roles in cancer pathogenesis.
Chauhan et al., Sioux Falls, United States. In Mol Cancer Res, 2011
The various functional domains of MUC13 may confer oncogenic potential to MUC13
Expression and functions of transmembrane mucin MUC13 in ovarian cancer.
Jaggi et al., Sioux Falls, United States. In Cancer Res, 2009
Findings show the aberrant expression of MUC13 in ovarian cancer and that its expression alters the cellular characteristics of SKOV-3 cells. This implies a significant role of MUC13 in ovarian cancer.
Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.
Johnston et al., Milwaukee, United States. In Ann Otol Rhinol Laryngol, 2008
Reflux laryngitis is associated with down-regulation of mucin gene expression.
Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease.
Schmitz et al., Regensburg, Germany. In J Mol Med (berl), 2006
Aberrant intestinal expression and allelic variant MUC13 is associated with inflammatory bowel disease.
Mucins and mucin binding proteins in colorectal cancer.
Bresalier et al., Houston, United States. In Cancer Metastasis Rev, 2004
There are two structurally and functionally distinct classes of mucins: secreted gel-forming mucins (MUC2, MUC5AC, MUC5B, and MUC6) and transmembrane mucins (MUC1, MUC3A, MUC3B, MUC4, MUC12, MUC17), although the products of some MUC genes do not fit well into either class (MUC7, MUC8, MUC9, MUC13, MUC15, MUC16).
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