Anti-complement sesquiterpenes from Viola yedoensis.
Shanghai, China. In Fitoterapia, Mar 2015
The sesquiterpenes 1-3, and 5-9 exhibited anti-complement activity against the classical pathway (CP) and the alternative pathway (AP) with the CH50 and AP50 values ranging from 0.14 to 0.37mg/mL and 0.32 to 0.54mg/mL, respectively.
Reversible reactions of ethylene with distannynes under ambient conditions.
Davis, United States. In Science, 2009
We show here that treatment of the distannynes Ar(iPr4)SnSnAr(iPr4) [Ar(iPr4) = C6H3-2,6(C6H3-2,6-iPr2)2, 1] or Ar(iPr8)SnSnAr(iPr8) [Ar(iPr8) = C6H-2,6(C6H2-2,4,6-iPr3)2-3,5-iPr2, 2] with ethylene under ambient conditions affords the cycloadducts Ar(iPr4) Sn(mu2:nu1:n1-C2H4)2Sn Ar(iPr4 (3) or Ar(iPrs) Sn(mu2:nu1:nu1-C2H4)2Sn AriPrs (4) that were structurally and spectroscopically characterized.
Rotavirus and reovirus modulation of the interferon response.
Raleigh, United States. In J Interferon Cytokine Res, 2009
First, the reovirus mu2 protein can induce an unusual nuclear accumulation of IRF9 and repress IFN-stimulated gene (ISG) expression, most likely by disrupting IRF9 function as part of the heterotrimeric transcription factor complex, ISGF3.
Regulation of Na,K-ATPase during acute lung injury.
Chicago, United States. In J Bioenerg Biomembr, 2007
This process promotes the alpha1-subunit recognition by the mu2 subunit of the adaptor protein-2 and its endocytosis trough a clathrin dependent mechanism.