▼Naloxegol for opioid-induced constipation.
In Drug Ther Bull, Dec 2015
▼Naloxegol (Moventig-AstraZeneca) is a peripherally acting mu-opioid receptor antagonist licensed for the treatment of opioid-induced constipation in adults who have had an inadequate response to laxative treatment.(1)
Opiate pharmacology and relief of pain.
New York City, United States. In J Clin Oncol, 2014
Evidence suggests that these variable responses among patients have a biologic basis and are likely to involve both biased agonism and the many mu opioid receptor subtypes that have been cloned.