Crosstalk between mTOR complexes.
Southampton, United Kingdom. In Nat Cell Biol, 05 Dec 2013
The mTOR protein kinase controls anabolic processes as part of mTOR complexes 1 and 2 (mTORC1 and mTORC2).
Regulatory Effects of Sestrin 3 (SESN3) in BCR-ABL Expressing Cells.
Chicago, United States. In Plos One, Dec 2012
We provide evidence that in BCR-ABL expressing cells, treatment with tyrosine kinase inhibitors (TKIs) results in upregulation of mRNA levels and protein expression of sestrin3 (SESN3), a unique cellular inhibitor of mTOR complex 1 (mTORC1).