Differential expression of genes involved in Bengal macrothrombocytopenia (BMTCP).
Mumbai, India. In Blood Cells Mol Dis, Dec 2015
Four genes i.e. myotubularin related protein 9 (MTMR9), iron responsive element binding protein 2 (IREB2), alpha tubulin(TUBA) and tyrosine kinase ligand (TKL) were found to be differentially expressed in patient platelets as compared to that of normal healthy controls which was further confirmed by quantitative RT PCR analysis.
Genetics of childhood-onset inflammatory bowel disease.
Edinburgh, United Kingdom. In Inflamm Bowel Dis, 2011
The newly identified loci and expression data suggest mutations in genes encoding IL-27, which is involved in Th17 effector cell physiology; MTMR3, which we demonstrate is an essential component of autophagy; and CAPN10, which is necessary in regulating endoplasmic reticulum stress.