gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Membrane-spanning 4-domains, subfamily A, member 7

MS4A7, CD20/FcepsilonRIbeta family member 4, CFFM4, high affinity immunoglobulin E receptor beta subunit
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CD20, IgE, fibrillin-1, FCER1B, MS4A12
Papers on MS4A7
Search for chromosome rearrangements: new approaches toward discovery of novel translocations in head and neck squamous cell carcinoma.
Smith et al., Rochester, United States. In Head Neck, 2013
RESULTS: Two novel cancer-specific translocations involving MGST3-ZMAT5 and MS4A7-C2CD3 were found in 2 of the tumor samples tested.
Expression of MS4A and TMEM176 Genes in Human B Lymphocytes.
Deans et al., Calgary, Canada. In Front Immunol, 2012
We investigated expression in primary human B-cells of the four MS4A genes previously shown to be expressed in human B-cell lines (MS4A4A, MS4A6A, MS4A7, MS4A8B), as well as two genes comprising the closely related TMEM176 gene family, with a view to identifying candidates for future investigation at the protein level.
The origins of human embryonic stem cells: a biological conundrum.
Adjaye et al., Berlin, Germany. In Cells Tissues Organs, 2007
These genes are involved in signaling cascades (SEMA7A and MAP3K10), cell proliferation (CUZD1 and MS4A7) and chromatin remodeling (H1FOO and HRMT1L4).
CFFM4: a new member of the CD20/FcepsilonRIbeta family.
Margolin et al., Houston, United States. In Immunogenetics, 2001
In this study, we report the identification, sequence, and expression profile of a new member of the CD20/FcepsilonRIbeta family, CD20/FcepsilonRIbeta family member 4 (CFFM4).
Structural organization of the human MS4A gene cluster on Chromosome 11q12.
Tedder et al., Durham, United States. In Immunogenetics, 2001
Sequence polymorphisms were identified in the MS4A6E gene and common splice variants were observed for the MS4A4A, MS4A5, MS4A6A, and MS4A7 genes.
Mutational analysis of the high affinity immunoglobulin E receptor beta subunit gene in asthma.
Walters et al., Melbourne, Australia. In Thorax, 1999
BACKGROUND: The gene for the beta subunit of the high affinity receptor for immunoglobulin E (FcepsilonRI-beta) on chromosome 11q13 is linked with clinical asthma and certain mutations have been identified.
share on facebooktweetadd +1mail to friends