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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 03 Oct 2014.

MRT4 Mrt4p

Mrt4
This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: caspase-3, YVH1, ST3Gal III, MARS, CAN
Papers on Mrt4
ST3GAL3 mutations impair the development of higher cognitive functions.
Kuss et al., Berlin, Germany. In Am J Hum Genet, 2011
ST3GAL3 resides on chromosome 1 within the MRT4 locus previously identified to associate with nonsyndromic autosomal recessive intellectual disability.
Genetic interactions of ribosome maturation factors Yvh1 and Mrt4 influence mRNA decay, glycogen accumulation, and the expression of early meiotic genes in Saccharomyces cerevisiae.
GeneRIF
Harashima et al., Suita, Japan. In J Biochem, 2011
the interaction between Mrt4 and Yvh1 is also essential for normal glycogen accumulation and mRNA decay as well as the induction of sporulation genes
Subcellular localization of ribosomal P0-like protein MRT4 is determined by its N-terminal domain.
GeneRIF
Tch├│rzewski et al., Lublin, Poland. In Int J Biochem Cell Biol, 2010
characterization of Mrt4; findings show Mrt4 is a trans-acting factor involved in ribosome maturation, with nucleus-cytoplasm shuttling capacity
Role and dynamics of the ribosomal protein P0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae.
GeneRIF
Ballesta et al., Madrid, Spain. In Nucleic Acids Res, 2009
loss of function of Mrt4 results in a deficit in 60S subunits, which is apparently due to impaired rRNA processing of 27S precursors
Ribosome stalk assembly requires the dual-specificity phosphatase Yvh1 for the exchange of Mrt4 with P0.
GeneRIF
Johnson et al., Austin, United States. In J Cell Biol, 2009
Ribosome stalk assembly requires the dual-specificity phosphatase Yvh1 for the exchange of Mrt4 with P0.
The amino terminal domain from Mrt4 protein can functionally replace the RNA binding domain of the ribosomal P0 protein.
GeneRIF
Ballesta et al., Madrid, Spain. In Nucleic Acids Res, 2009
results indicate that Mrt4 and P0 bind to the same site in the 25S rRNA.
Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover.
Jacobson et al., Worcester, United States. In Genetics, 1999
Complementation of the growth and mRNA decay defects, and genetic experiments, revealed that ts1189 is mutated in the previously unknown MRT4 gene, ts942 is mutated in GRC5 (encoding the L9 ribosomal protein), ts817 contains a mutation in SLA2 (encoding a membrane protein), and ts1100 contains a mutation in THS1 (encoding the threonyl-tRNA synthetase).
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