Magnetic Resonance Spectroscopy of siRNA-Based Cancer Therapy.
Baltimore, United States. In Methods Mol Biol, Dec 2015
Here we describe the use of siRNA to downregulate choline kinase, a critical enzyme in choline phospholipid metabolism of cancer cells and tumors, and the use of (1)H MRS of cells and (1)H magnetic resonance spectroscopic imaging (MRSI) of tumors to assess the efficacy of the downregulation.
Albuquerque, United States. In Neuroimage, 2012
The rapid development of fMRI was paralleled early on by the adaptation of MR spectroscopic imaging (MRSI) methods to quantify water relaxation changes during brain activation.