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Mitochondrial ribosomal protein L39

MRP-L5
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID
Papers on MRP-L5
Heart-specific splice-variant of a human mitochondrial ribosomal protein (mRNA processing; tissue specific splicing).
Fischel-Ghodsian et al., Los Angeles, United States. In Gene, 2001
The 338 amino acid (aa) residues long MRP-L5 was identified (O'Brien et al., 1999.
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