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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Mortality factor 4 like 2

MRGX, MORF-related gene X, MORF4L2
Top mentioned proteins: MRG15, Histone, HAD, BLBP, CAN
Papers on MRGX
Gene transcript analysis blood values correlate with ⁶⁸Ga-DOTA-somatostatin analog (SSA) PET/CT imaging in neuroendocrine tumors and can define disease status.
New
Drozdov et al., Milano, Italy. In Eur J Nucl Med Mol Imaging, Aug 2015
The genes MORF4L2 and somatostatin receptors SSTR1, 3, and 5 exhibited the highest correlation with SUVmax.
The Origin, Expression, Function and Future Research Focus of a G Protein-coupled Receptor, Mas-related Gene X2 (MrgX2).
Review
New
Sha et al., Shenzhen, China. In Prog Histochem Cytochem, Jul 2015
Human MRGX proteins are G protein-coupled 7-transmembrane proteins sharing 41-52% amino acid identity with each other, but have no orthologs in rodents.
Enhancement of tumor initiation and expression of KCNMA1, MORF4L2 and ASPM genes in the adenocarcinoma of lung xenograft after vorinostat treatment.
New
Liu et al., Taipei, Taiwan. In Oncotarget, May 2015
However, SAHA significantly enhanced the tumor initiating capacity and the expression of malignant genes such as KCNMA1, MORF4L2 and ASPM in the remaining living ALDHbr cells.
Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators.
Mann et al., Martinsried, Germany. In Genome Res, 2013
Conversely, knockdown of MORF4L2, a component of the NuA4 histone acetyltransferase complex, reduced TERRA levels both globally and for telomere-bound TERRA.
Differential Expression of Gene Profiles in MRGX-treated Lung Cancer.
Jang et al., Taejŏn, South Korea. In J Pharmacopuncture, 2013
OBJECTIVES: Modified regular ginseng extract (MRGX) has stronger anti-cancer activity-possessing gensenoside profiles.
Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.
Lightcap et al., Cambridge, United States. In Mol Cell Proteomics, 2011
Proteins such as MLX, EID1, KLF5, ORC6L, MAGEA6, MORF4L2, MRFAP1, MORF4L1, and TAX1BP1 are rapidly stabilized by MLN4924, suggesting that they are novel CRL substrates.
Emerging role of the MORF/MRG gene family in various biological processes, including aging.
Review
Pereira-Smith et al., San Antonio, United States. In Ann N Y Acad Sci, 2010
Morf4 is a member of a family of seven genes, and Morf-related genes (Mrg) on chromosomes 15 (Mrg15) and X (MrgX) are also expressed.
Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.
GeneRIF
Singer et al., New York City, United States. In Cancer Res, 2008
The transcriptional status of four key genes, thymidylate synthase (TYMS), MORF-related gene X (MRGX), Bcl2-antagonist/killer (BAK), and ATPase, Cu(2+) transporting beta polypeptide (ATP7B), can accurately predict response to 5-FU.
Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia.
MacAulay et al., Vancouver, Canada. In Bmc Genomics, 2007
Evaluation of these genes through network interactions identified multiple candidates that influence regulation of cellular transcription through chromatin remodelling (SMARCC1, NCOR1, MRFAP1 and MORF4L2).
Direct effect of cortistatin on GH release from cultured pituitary cells in the rat.
Martynska et al., Warsaw, Poland. In Neuro Endocrinol Lett, 2006
It has been reported that a receptor called MrgX(2) is able to selectively bind both CST-17 and CST-14 rather than SS.
Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors.
Nash et al., San Diego, United States. In Br J Pharmacol, 2006
MrgX receptors were cloned from rhesus monkey and functionally characterized alongside their human orthologs.
MrgX is not essential for cell growth and development in the mouse.
GeneRIF
Pereira-Smith et al., San Antonio, United States. In Mol Cell Biol, 2005
Data show that MRGX is ubiquitously expressed in all tissues of adult mice and also during embryogenesis, and overlaps with its homolog Mrg15.
Cloning and expression of MRG receptors in macaque, mouse, and human.
Bates et al., Cambridge, United States. In Brain Res Mol Brain Res, 2005
Here we report the identification of MRGD, MRGE, and several MRGX orthologs in the crab-eating macaque, Macaca fascicularis.
MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.
GeneRIF
Pereira-Smith et al., San Antonio, United States. In J Biol Chem, 2004
can repress or activate the B-myb promoter depending on the cell type studied, suggesting that there may be tissue-specific functions of this protein
Identification of genes involved in cell senescence and immortalization: potential implications for tissue ageing.
Review
Pereira-Smith et al., Houston, United States. In Novartis Found Symp, 2000
It is a member of a family of seven genes and only MORF4 and the MORF-related genes MRG15 and MRGX are expressed.
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