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Motile sperm domain containing 3

MOSPD3, cds3
This gene encodes a multi-pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: IL-17, endoglin, caspase-2, caspase-3, FACT
Papers on MOSPD3
A Role for MOSPD1 in Mesenchymal Stem Cell Proliferation and Differentiation.
Forrester et al., Los Angeles, United States. In Stem Cells, Oct 2015
Phenotypic deficiencies exhibited by MOSPD1-null ESCs were rescued by exogenous expression of MOSPD1, but not MOSPD3 indicating distinct functional properties of these closely related genes.
MicroRNA844-Guided Downregulation of Cytidinephosphate Diacylglycerol Synthase3 (CDS3) mRNA Affects the Response of Arabidopsis thaliana to Bacteria and Fungi.
Kang et al., Kwangju, South Korea. In Mol Plant Microbe Interact, Aug 2015
Although no cleavage was observed at the predicted cleavage site of the putative target mRNA, cytidinephosphate diacylglycerol synthase3 (CDS3), cleavage was observed at 6, 12, 21, or 52 bases upstream of the predicted cleavage site of CDS3 mRNA, and the level of CDS3 mRNA was downregulated by the overexpression of miR844, implying that miR844 influences CDS3 transcript level.
Magnetic bead-based separation of sperm from buccal epithelial cells using a monoclonal antibody against MOSPD3.
Li et al., Jinan, China. In Int J Legal Med, 2014
To investigate the feasibility of magnetic bead-based separation of sperm from cell mixtures using a monoclonal antibody against MOSPD3 (motile sperm domain-containing protein 3), 30 cell samples were prepared by mixing 10(4) female buccal epithelial cells with sperm cells of varying densities (10(3), 10(4), or 10(5) cells/mL).
Mospd1, a new player in mesenchymal versus epidermal cell differentiation.
Varga et al., Vienna, Austria. In J Cell Physiol, 2011
Mospd1 codes for a small protein with unknown physiological function, which is part of a family of genes, including Mospd2 and Mospd3, defined by the presence of the major sperm protein domain and two transmembrane domains.
Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer.
Reddi et al., Sacramento, United States. In Cancer Res, 2006
We found that IL-17RL was expressed at significantly higher levels in several androgen-independent prostate cancer cell lines (PC3, DU145, cds1, cds2, and cds3) and tumors compared with the androgen-dependent cell lines (LNCaP and MLC-SV40) and tumors.
A novel transmembrane MSP-containing protein that plays a role in right ventricle development.
Forrester et al., Edinburgh, United Kingdom. In Genomics, 2004
Deletion fo the Mospd3 locus is mutagenic and breeding to homozygosity results in a characteristic right ventricle defect and neonatal lethality in 50% of mice.
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