Tanabe et al., Ann Arbor, United States. In Nat Med, Mar 2013
We show here that lysine-specific demethylase 1 (LSD1) inhibition by RNAi in human erythroid cells or by the monoamine oxidase inhibitor tranylcypromine in human erythroid cells or β-type globin-transgenic mice enhances γ-globin expression.
The discrimination of melancholia and atypical depression based on a differential response to the specific type of antidepressant drugs (e. g., tricyclic antidepressants or monoamine oxidase inhibitors) is unlikely to be proven.
Guarente et al., Cambridge, United States. In Cell, 2012
Here we used mice with increased or decreased brain SIRT1 to show that this sirtuin regulates anxiety and exploratory drive by activating transcription of the gene encoding the monoamine oxidase A (MAO-A) to reduce serotonin levels in the brain.
Nakamura et al., Suita, Japan. In Biochemistry, 2009
Principal component analysis points to the three domains that define MaoA's global dynamics. A pronounced anticorrelation exists in the motions of MaoA domain M relative to domains S and F in the membrane-bound compared to the membrane-unbound system.
Davenport et al., Cambridge, United Kingdom. In Pharmacol Rev, 2009
Concomitant ingestion of these foodstuffs with monoamine oxidase inhibitors may result in the hypertensive crisis known as the "beer, wine, and cheese effect" attributed to their sympathomimetic action.
Bhattacharya et al., Benares, India. In Pharm Res, 1985
Thirty-three N (3)-2-, -3- or -4-substituted aryl-N (1)-(alkyl/aryl/substituted aryl)-triazene N (1)-oxides were synthesized and evaluated for their anticonvulsant and monoamine oxidase (MAO) inhibitory activities.
Telegdy et al., Szeged, Hungary. In Neurochem Res, 1977
The action of 1.0 and 10.0 mg/kg (i.p.) of corticosterone on serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) contents and on serotonin turnover, measured by an MAO-inhibitor method, was studied at 30 and 120 min after administration.
Aprison et al., Indianapolis, United States. In Neurochem Res, 1976
Studies were conducted in vitro in the presence of either 2×10(-5) M tranylcypromine, which inhibited the MAO activity of both the extrasynaptosomal mitochondria and the mitochondria contained within the nerve endings (intrasynaptosomal mitochondria), or 2×10(-5) M nialamide, which inhibited the MAO activity of the extrasynaptosomal mitochondria under the experimental conditions used.