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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

NLR family, pyrin domain containing 12

Monarch, RNO, RNO2, Monarch-1
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, V1a, OUT
Papers on Monarch
Bioactivity and laundering resistance of five commercially available, factory-treated permethrin-impregnated fabrics for the prevention of mosquito-borne diseases: the need for a standardized testing and licensing procedure.
New
Uedelhoven et al., Koblenz, Germany. In Parasitol Res, Feb 2016
The aim of this study was to analyze the insecticide content, contact toxicity, laundering resistance, and residual activity of five commercially available and commonly used permethrin-treated fabrics-Insect Shield, ExOfficio, Sol's Monarch T-shirts, battle dress uniforms (BDUs), and Labonal socks-against vector-competent Aedes aegypti, Anopheles stephensi, and Culex pipiens mosquitoes under laboratory conditions.
Roflumilast inhibits leukocyte-platelet interactions and prevents the prothrombotic functions of polymorphonuclear leukocytes and monocytes.
New
Evangelista et al., Italy. In J Thromb Haemost, Jan 2016
Objectives We tested the hypothesis that roflumilast N-oxide (RNO), the active metabolite of roflumilast, curbs the molecular mechanisms required for leukocyte-platelet (PLT) interactions and prevents the prothrombotic functions of polymorphonuclear leukocytes (PMNs) and monocytes (MNs).
The effect of cations on NO2 production from the photolysis of aqueous thin water films of nitrate salts.
New
Finlayson-Pitts et al., Irvine, United States. In Phys Chem Chem Phys, Jan 2016
The nitrate salts fall into three groups based on their observed rate of NO2 formation (RNO2): (1) RbNO3 and KNO3, which readily produce NO2 (RNO2 > 3 ppb min(-1)), (2) Ca(NO3)2, which produces NO2 more slowly (RNO2 < 1 ppb min(-1)), and (3) Mg(NO3)2 and NaNO3, which lie between the other two groups.
Efficacy of protease inhibitor monotherapy vs. triple therapy: meta-analysis of data from 2303 patients in 13 randomized trials.
New
Hadacek et al., Madrid, Spain. In Hiv Med, Jan 2016
RESULTS: There were 2303 patients from 13 different randomized clinical trials of darunavir/r monotherapy (n = 784: MONET, MONOI, Monarch and PROTEA), lopinavir/r monotherapy (n = 829: OK pilot, OK-04, KalMo, KALESOLO, KRETA, MOST and DREAM), atazanavir/r monotherapy (n = 103: MODAT), or all three (n = 587: PIVOT).
Six-coordinate ferric porphyrins containing bidentate N-t-butyl-N-nitrosohydroxylaminato ligands: structure, magnetism, IR spectroelectrochemisty, and reactivity.
New
Richter-Addo et al., Norman, United States. In Dalton Trans, Dec 2015
Reactions of and with a histidine mimic (1-methylimidazole) generate RNO and NO, both of which may bind to the metal center if sterics allow, as shown by a comparative study with the Cupferron complex (T(p-OMe)PP)Fe(η(2)-ON(Ph)NO).
Prospective evaluation of intraoperative intraocular lens stress fracture during cataract surgery.
New
Tokarewicz et al., London, Canada. In J Cataract Refract Surg, Nov 2015
The 2 groups only differed in the use of Monarch IOL delivery cartridges for insertion of an Acrysof IQ SN60WF IOL.
Neurobiology of Monarch Butterfly Migration.
New
Merlin et al., College Station, United States. In Annu Rev Entomol, Nov 2015
UNASSIGNED: Studies of the migration of the eastern North American monarch butterfly (Danaus plexippus) have revealed mechanisms behind its navigation.
Disease insights through cross-species phenotype comparisons.
Review
New
Smedley et al., Portland, United States. In Mamm Genome, Oct 2015
In this review, we highlight the challenges in comparing human clinical phenotypes with mouse phenotypes and some of the solutions that have been developed by members of the Monarch Initiative.
Do Healthy Monarchs Migrate Farther? Tracking Natal Origins of Parasitized vs. Uninfected Monarch Butterflies Overwintering in Mexico.
Wassenaar et al., Saskatoon, Canada. In Plos One, 2014
We examined wild monarch butterflies (Danaus plexippus) to investigate the potential costs of the protozoan Ophryocystis elektroscirrha on migratory success.
The NLRP12 pyrin domain: structure, dynamics, and functional insights.
GeneRIF
Peti et al., Providence, United States. In J Mol Biol, 2011
The authors report the first in vitro confirmed non-homotypic interaction between NLRP12 pyrin domain and the pro-apoptotic protein Fas-associated factor 1 (FAF-1), which links the innate immune system to apoptotic signaling.
Identification and functional consequences of a recurrent NLRP12 missense mutation in periodic fever syndromes.
GeneRIF
Amselem et al., Paris, France. In Arthritis Rheum, 2011
NLRP12 missense mutation in periodic fever syndromes; study provides evidence of deleterious effect of an NLRP12 missense mutation; this newly identified molecular defect emphasizes the crucial role played by NLRP12 in autoinflammation
Navigational mechanisms of migrating monarch butterflies.
Review
Merlin et al., Worcester, United States. In Trends Neurosci, 2010
Recent studies of the iconic fall migration of monarch butterflies have illuminated the mechanisms behind their southward navigation while using a time-compensated sun compass.
Trends in functional rhinoplasty 2008.
Review
Constantinides et al., New York City, United States. In Curr Opin Otolaryngol Head Neck Surg, 2009
RECENT FINDINGS: Surgical techniques for improving the internal nasal valve include upper lateral cartilage fold-in flap, splay graft, alar batten graft, Z-plasty, and the alloplastic Monarch implant.
Nursing leadership and management effects work environments.
Review
Tomey, Fort Myers, United States. In J Nurs Manag, 2009
KEY ISSUES: The 14 forces of magnetism as identified by Unden and Monarch were: '1.
Clocks, cryptochromes and Monarch migrations.
Review
Kyriacou, Leicester, United Kingdom. In J Biol, 2008
The annual migration of the Monarch butterfly (Danaus plexippus) from eastern North America to central Mexico is one of nature's most inspiring spectacles.
Inflammasome mRNA expression in human monocytes during early septic shock.
GeneRIF
Wewers et al., Columbus, United States. In Am J Respir Crit Care Med, 2008
Relative copy numbers for the inflammasome mRNAs for ASC, caspase-1, NALP1, and Pypaf-7 were significantly lower in patients with septic shock compared with critically ill control subjects.
ATP binding by monarch-1/NLRP12 is critical for its inhibitory function.
GeneRIF
Ting et al., Chapel Hill, United States. In Mol Cell Biol, 2008
ATP binding by NLRP12 is critical for its inhibitory function.
Mutations in NALP12 cause hereditary periodic fever syndromes.
GeneRIF
Amselem et al., Paris, France. In Proc Natl Acad Sci U S A, 2008
Two mutations, nonsense and splice site, were identified in NALP12 in two families with periodic fever syndromes.
Mortality of the Monarch Butterfly (Danaus plexippus L.): Avian Predation at Five Overwintering Sites in Mexico.
Impact
Brower et al., In Science, 1979
Analyses of predated butterflies on the forest floor at five monarch overwintering sites in Mexico and observations of birds foraging in mixed flocks indicate that individual birds of several species have learned to penetrate the monarch's cardenolide-based chemical defense.
Sex pheromone of the queen bufferfly: electroantennogram responses.
Impact
Seibt et al., In Science, 1969
Antennae of another related species, the monarch (Danaus plexippus), respond to the same stimuli as does the queen.
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