A simple and fast densitometric method for the analysis of tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta and in the ventral tegmental area
In PLoS ONE, 2004
... Antibodies against SPARC (Santa Cruz Biotechnology, Santa Cruz, CA, USA), (p-)SAPK/JNK, (p-)ERK1/2, (p-)p-38, MMP-7 (Cell signaling technology, Danvers, MA,USA), VEGF, ...
Constitutive activation of STAT3 in breast cancer cells: A review.
Pullman, United States. In Int J Cancer, 11 Dec 2015
Aberrant STAT3 signaling promotes breast tumor progression through deregulation of the expression of downstream target genes which control proliferation (Bcl-2, Bcl-xL, Survivin, Cyclin D1, c-Myc, Mcl-1), angiogenesis (Hif1α, VEGF), and epithelial-mesenchymal transition (Vimentin, TWIST, MMP-9, MMP-7).
Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip.
Uppsala, Sweden. In Stroke, 05 Dec 2015
In predefined secondary meta-analyses of individual data, interleukin-27 subunit α, growth/differentiation factor 15, urokinase plasminogen activator surface receptor, tumor necrosis factor receptor superfamily member 6, macrophage colony-stimulating factor 1, and matrix metalloproteinase-7 were also potential risk markers for ischemic stroke after adjustment for multiple comparisons (P<0.0006).
Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters.
Khon Kaen, Thailand. In Nanomedicine, 02 Dec 2015
OP+NEC treatment reduced the PDF by suppression of fibrotic markers (hydroxyproline content, α-SMA, CTGF, fibronectin, collagen I and III), cytokines (TGF-β and TNF-α) and TIMP-1, 2, 3 expression and upregulation of MMP-7, 13 genes, whereas OP, OP+carrier and OP+Cur did not.
Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease.
Guangzhou, China. In Nat Rev Nephrol, Sep 2015
Mechanistically, Wnt/β-catenin controls the expression of several key mediators implicated in podocytopathies, including Snail1, the renin-angiotensin system and matrix metalloproteinase 7. Wnt/β-catenin also negatively regulates Wilms tumour protein, a crucial transcription factor that safeguards podocyte integrity.
Matrix remodeling by MMPs during wound repair.
Los Angeles, United States. In Matrix Biol, May 2015
For wound closure, we discuss how two MMPs - MMP1 in human epidermis and MMP7 in mucosal epithelia - facilitate re-epithelialization by cleaving different ECM or ECM-associated proteins to affect similar integrin:matrix adhesion.
[Genetic and environmental aspects of mathematical disabilities].
In Genetika, Mar 2015
The results of the second approach demonstrates that the matrix metalloproteinase 7 gene (MMP7), the glutamate receptor ionotropic kainate 1 gene (GRIK1), and the dynein axonemal heavy chain 5 gene (DNA H5) are responsible for developing mathematical disabilities.
Wnt/β-catenin signaling and kidney fibrosis.
Pittsburgh, United States. In Kidney Int Suppl (2011), Nov 2014
In kidney cells, Wnt/β-catenin promotes the expression of numerous fibrosis-related genes such as Snail1, plasminogen activator inhibitor-1, and matrix metalloproteinase-7.