A simple and fast densitometric method for the analysis of tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta and in the ventral tegmental area
In PLoS ONE, 2004
... Antibodies against SPARC (Santa Cruz Biotechnology, Santa Cruz, CA, USA), (p-)SAPK/JNK, (p-)ERK1/2, (p-)p-38, MMP-7 (Cell signaling technology, Danvers, MA,USA), VEGF, ...
Alcohol Consumption, Wnt/β-Catenin Signaling, and Hepatocarcinogenesis.
Little Rock, United States. In Adv Exp Med Biol, 31 Dec 2014
Analysis of EtOH-treated livers from a previously published rat model of chronic liver disease revealed increases in hepatocyte proliferation accompanied by a hepatic depletion of retinol and retinoic acid stores (p < 0.05), nuclear accumulation of β-catenin (p < 0.05), increased cytosolic expression p-GSK3β (p < 0.05), significant upregulation of soluble Wnts, Wnt2, and Wnt7a, and increased expression of several β-catenin targets involved in tumor promotion and progression, cyclin D1, c-myc, WISP1, and MMP7 (p < 0.05).
CD151 in cancer progression and metastasis: a complex scenario.
Gdańsk, Poland. In Lab Invest, Jan 2014
The molecular mechanism of CD151 in cancer is based on its ability to organize distribution and function of interacting proteins, ie, laminin-binding integrins (α3β1, α6β1 and α6β4), receptors for growth factors (HGFR, EGFR and TGF-β1R) and matrix metalloproteinases (MMP-7, MMP-2 and MMP-9), which indicates its importance in disease development.
Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling.
Hangzhou, China. In Mediators Inflamm, 2012
MMPs including MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, and MT1-MMP, are stimulated and activated by various stimuli in vascular tissues.