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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 27 Feb 2015.

Interleukin 17F

mL-1, IL-17F
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: IL-17, CAN, IL-21, ACID, HAD
Papers on mL-1
Green Approach for Ultratrace Determination of Divalent Metal Ions and Arsenic Species Using Total-Reflection X-ray Fluorescence Spectrometry and Mercapto-Modified Graphene Oxide Nanosheets as a Novel Adsorbent.
Queralt et al., In Anal Chem, 23 Mar 2015
The high enrichment factor of 150 allows obtaining detection limits of 0.11, 0.078, 0.079, 0.064, 0.054 and 0.083 ng mL-1 for Co(II), Ni(II), Cu(II), As(III), Cd(II) and Pb(II), respectively.
Polydiacetylene Nanovesicles as Carriers of Natural Phenylpropanoids for Creating Antimicrobial Food-contact Surfaces.
Rodov et al., In J Agric Food Chem, 20 Mar 2015
coli) and vegetative cells of Gram-positive (Bacillus cereus) bacteria reducing their counts from 5 log CFU mL-1 to undetectable level within 8 h.
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
Dixit et al., San Francisco, United States. In Nature, 19 Mar 2015
T-helper type 17 (TH17) cells that produce the cytokines interleukin-17A (IL-17A) and IL-17F are implicated in the pathogenesis of several autoimmune diseases.
A New Perspective of Lysosomal Cation Channel-Dependent Homeostasis in Alzheimer's Disease.
Omabe et al., Halifax, Canada. In Mol Neurobiol, 18 Mar 2015
The best characterized so far among these channels is the ML1 isoform of TRP.
NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis.
Finotto et al., Erlangen, Germany. In Eur J Immunol, 16 Mar 2015
NFATc1-deficient CD4(+) T cells polarized under Th17 conditions express reduced levels of the Th17-associated transcription factor RORγT as well as the Th17-associated cytokines IL-17A, IL-17F, IL-21 and IL-10.
Miltefosine is active against Sporothrix brasiliensis isolates with in vitro low susceptibility to amphotericin B or itraconazole.
Rozental et al., Rio de Janeiro, Brazil. In J Med Microbiol, 13 Mar 2015
Miltefosine had fungicidal activity, with minimum inhibitory concentration (MIC) values between 1-2 µg.mL-1.
Cytokine crowdsourcing: multicellular production of TH17-associated cytokines.
O'Connor et al., Albany, United States. In J Leukoc Biol, 29 Jan 2015
IL-17A is often present in a composite milieu that includes cytokines produced by TH17 cells (i.e., IL-17F, IL-21, IL-22, and IL-26) or associated with other T cell lineages (e.g., IFN-γ).
Molecular underpinnings of Th17 immune-regulation and their implications in autoimmune diabetes.
Subramaniyam et al., Tiruchchirāppalli, India. In Cytokine, 12 Jan 2015
Th17 cells are characterized by the expression of effector cytokines IL-17A, IL-17F, IL-21 and IL-22, and lineage specific transcription factor ROR-C in human and ROR-γt in mice.
The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.
Xu et al., Ann Arbor, United States. In Nat Med, Oct 2014
MCOLN1 (also known as TRPML1, ML1) is an endosomal and lysosomal Ca(2+) channel whose human mutations cause mucolipidosis IV (ML4), a neurodegenerative disease with motor disabilities.
Targeting Th17 cells in autoimmune diseases.
Yamagata et al., Cambridge, United States. In Trends Pharmacol Sci, Oct 2014
Given that Th17 cells express IL-17 together with many other proinflammatory cytokines [IL-17F, IL-22, IL-26, and granulocyte-macrophage colony-stimulating factor (GM-CSF)], targeting the Th17 cell lineage may be superior to blocking a single effector cytokine.
Interleukin-17 in human inflammatory diseases.
Shahneh et al., Tehrān, Iran. In Postepy Dermatol Alergol, Aug 2014
Recently discovered related molecules are forming a family of cytokines, the IL-17 family, IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F.
Anticytokine autoantibody-associated immunodeficiency.
Browne, Bethesda, United States. In Annu Rev Immunol, 2013
Examples include anti-interferon (IFN)-γ autoantibodies and disseminated nontuberculous mycobacteria; anti-granulocyte macrophage colony-stimulating factor autoantibodies and cryptococcal meningitis; anti-interleukin (IL)-6 autoantibodies and staphylococcal skin infection; and anti-IL-17A, anti-IL-17F, or anti-IL-22 autoantibodies and mucocutaneous candidiasis in the setting of either APECED (autoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy syndrome) or thymoma.
Brodalumab: an evidence-based review of its potential in the treatment of moderate-to-severe psoriasis.
Santos-Silva et al., Portugal. In Core Evid, 2013
Brodalumab is a human monoclonal antibody that targets IL-17 receptor A, blocking the effects of IL-17A, IL-17F, and IL-17E.
An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
Casanova et al., New York City, United States. In Immunity, 2013
Patients with inborn errors of interleukin-17F (IL-17F) or IL-17RA display chronic mucocutaneous candidiasis (CMC).
Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.
Rawlings et al., Córdoba, Argentina. In Nat Immunol, 2013
With both mouse and human primary B cells, we found that exposure to parasite-derived trans-sialidase in vitro was sufficient to trigger modification of the cell-surface mucin CD45, which led to signaling dependent on the kinase Btk and production of IL-17A or IL-17F via a transcriptional program independent of the transcription factors RORγt and Ahr.
The IL6 gene polymorphism -634C>G and IL17F gene polymorphism 7488T>C influence bone mineral density in young and elderly Japanese women.
Fuke et al., Hachiōji, Japan. In Gene, 2012
IL17F gene polymorphism 7488T>C influences bone mineral density.
Interleukin-33 induces interleukin-17F in bronchial epithelial cells.
Hizawa et al., Tsukuba, Japan. In Allergy, 2012
data suggest that the IL-33/IL-17F axis is involved in allergic airway inflammation
Association analysis of IL-17A and IL-17F polymorphisms in Chinese Han women with breast cancer.
Pang et al., Harbin, China. In Plos One, 2011
Results suggested that single-nucleotide polymorphisms (SNPs) in IL-17A but not IL-17F were associated with the risk of breast cancer.
A protective role by interleukin-17F in colon tumorigenesis.
Dong et al., Wuhan, China. In Plos One, 2011
Together, our findings demonstrate a protective role for IL-17F in colon cancer development, possibly via inhibiting tumor angiogenesis
[Dynamics of serum IL-17A, IL-17F and IL-23 in patients with inflammatory bowel disease].
Efremov et al., In Eksp Klin Gastroenterol, 2010
Dynamics of serum IL-17A, IL-17F and IL-23 in patients with inflammatory bowel disease
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