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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 11 Dec 2014.

Interleukin 17F

mL-1, IL-17F
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: IL-17, CAN, IL-21, ACID, HAD
Papers on mL-1
Self-assembly of amphiphilic Janus particles into monolayer capsules for enhanced enzyme catalysis in organic media.
New
He et al., In Acs Appl Mater Interfaces, 05 Jan 2015
It was found that the specific activity of the encapsulated enzymes (28.7 U mL-1) was more than 5.6 times higher than that of free enzymes in a biphasic system (5.1 U mL-1).
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
New
Impact
Dixit et al., San Francisco, United States. In Nature, 03 Jan 2015
UNLABELLED: T-helper type 17 (TH17) cells that produce the cytokines interleukin-17A (IL-17A) and IL-17F are implicated in the pathogenesis of several autoimmune diseases.
Dendrimer Nanocarriers for Transport Modulation across Models of the Pulmonary Epithelium.
New
da Rocha et al., In Mol Pharm, 02 Jan 2015
The exposure obtained for the DNC with 25PEG was determined to be very high, with peak plasma concentrations reaching 5 μg.mL-1 within 3h.
The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response.
New
Sawalha et al., Ann Arbor, United States. In Clin Immunol, 29 Nov 2014
Our data also suggest a robust pro-inflammatory epigenetic signature in double negative T cells, consistent with a transcriptional permissiveness in key inflammatory cytokines including IFNγ, IL-17F, IL-12B, IL-5, IL-18, TNFSF11 (RANKL), and TNFSF13B (BLYS or BAFF).
Cytokine gene expression profiles in chicken spleen and intestinal tissues during Ascaridia galli infection.
New
Juul-Madsen et al., Århus, Denmark. In Vet Parasitol, 24 Nov 2014
By real-time quantitative RT-PCR, the relative gene expression of the T helper 1 (Th1) cytokine IFN-γ, the T helper 2 (Th2) cytokine IL-13, the anti-inflammatory cytokines IL-10 and TGF-β4 and the pro-inflammatory cytokine IL-17F were determined over a period of 3 weeks in A. galli and non-A.
The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.
New
Impact
Xu et al., Ann Arbor, United States. In Nat Med, Oct 2014
MCOLN1 (also known as TRPML1, ML1) is an endosomal and lysosomal Ca(2+) channel whose human mutations cause mucolipidosis IV (ML4), a neurodegenerative disease with motor disabilities.
Interleukin-17 in human inflammatory diseases.
Review
New
Shahneh et al., Tehrān, Iran. In Postepy Dermatol Alergol, Aug 2014
Recently discovered related molecules are forming a family of cytokines, the IL-17 family, IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F.
Role of TH17 cytokines in the control of colorectal cancer.
Review
New
Stolfi et al., Roma, Italy. In Oncoimmunology, Jan 2014
Studies with murine models of CRC have delineated the mechanisms by which TH17 cytokines, notably, interleukin (IL)-17A, IL-17F, IL-21, and IL-22, regulate oncogenesis and tumor progression, paving the way to the development of novel anticancer drugs.
Brodalumab: an evidence-based review of its potential in the treatment of moderate-to-severe psoriasis.
Review
New
Santos-Silva et al., Portugal. In Core Evid, Dec 2013
Brodalumab is a human monoclonal antibody that targets IL-17 receptor A, blocking the effects of IL-17A, IL-17F, and IL-17E.
Anticytokine autoantibody-associated immunodeficiency.
Review
New
Impact
Browne, Bethesda, United States. In Annu Rev Immunol, Dec 2013
Examples include anti-interferon (IFN)-γ autoantibodies and disseminated nontuberculous mycobacteria; anti-granulocyte macrophage colony-stimulating factor autoantibodies and cryptococcal meningitis; anti-interleukin (IL)-6 autoantibodies and staphylococcal skin infection; and anti-IL-17A, anti-IL-17F, or anti-IL-22 autoantibodies and mucocutaneous candidiasis in the setting of either APECED (autoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy syndrome) or thymoma.
[Role of Th17 lymphocytes in pathogenesis of colorectal cancer].
Review
New
Adamski et al., In Postepy Hig Med Dosw (online), Dec 2013
Th17 lymphocytes produce a number of pro-inflammatory cytokines, such as interleukin (IL)-17A, IL-17F, IL-21, IL-22 and tumor necrosis factor (TNF)-a, and play a key role in mucosal defense against various pathogens.
IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma.
New
Al-Muhsen et al., Riyadh, Saudi Arabia. In Plos One, Dec 2013
Using an in-vitro migration assay, B cells were shown to migrate towards both IL-17A and IL-17F.
Phage Therapy as an Approach to Prevent Vibrio anguillarum Infections in Fish Larvae Production.
New
Almeida et al., Aveiro, Portugal. In Plos One, Dec 2013
Two groups of zebrafish larvae were infected with V. anguillarum (∼106 CFU mL-1) and one was later treated with a phage lysate (∼108 PFU mL-1).
An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
New
Impact
Casanova et al., New York City, United States. In Immunity, Nov 2013
Patients with inborn errors of interleukin-17F (IL-17F) or IL-17RA display chronic mucocutaneous candidiasis (CMC).
Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.
New
Impact
Rawlings et al., Córdoba, Argentina. In Nat Immunol, May 2013
With both mouse and human primary B cells, we found that exposure to parasite-derived trans-sialidase in vitro was sufficient to trigger modification of the cell-surface mucin CD45, which led to signaling dependent on the kinase Btk and production of IL-17A or IL-17F via a transcriptional program independent of the transcription factors RORγt and Ahr.
The IL6 gene polymorphism -634C>G and IL17F gene polymorphism 7488T>C influence bone mineral density in young and elderly Japanese women.
GeneRIF
Fuke et al., Hachiōji, Japan. In Gene, 2012
IL17F gene polymorphism 7488T>C influences bone mineral density.
Interleukin-33 induces interleukin-17F in bronchial epithelial cells.
GeneRIF
Hizawa et al., Tsukuba, Japan. In Allergy, 2012
data suggest that the IL-33/IL-17F axis is involved in allergic airway inflammation
Association analysis of IL-17A and IL-17F polymorphisms in Chinese Han women with breast cancer.
GeneRIF
Pang et al., Harbin, China. In Plos One, 2011
Results suggested that single-nucleotide polymorphisms (SNPs) in IL-17A but not IL-17F were associated with the risk of breast cancer.
A protective role by interleukin-17F in colon tumorigenesis.
GeneRIF
Dong et al., Wuhan, China. In Plos One, 2011
Together, our findings demonstrate a protective role for IL-17F in colon cancer development, possibly via inhibiting tumor angiogenesis
[Dynamics of serum IL-17A, IL-17F and IL-23 in patients with inflammatory bowel disease].
GeneRIF
Efremov et al., In Eksp Klin Gastroenterol, 2010
Dynamics of serum IL-17A, IL-17F and IL-23 in patients with inflammatory bowel disease
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