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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 Mar 2014.

Interleukin 17F

mL-1, IL-17F
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: IL-17, CAN, IL-21, ACID, HAD
Papers on mL-1
Anticytokine autoantibody-associated immunodeficiency.
New
Impact
Browne, Bethesda, United States. In Annu Rev Immunol, 21 Apr 2014
Examples include anti-interferon (IFN)-γ autoantibodies and disseminated nontuberculous mycobacteria; anti-granulocyte macrophage colony-stimulating factor autoantibodies and cryptococcal meningitis; anti-interleukin (IL)-6 autoantibodies and staphylococcal skin infection; and anti-IL-17A, anti-IL-17F, or anti-IL-22 autoantibodies and mucocutaneous candidiasis in the setting of either APECED (autoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy syndrome) or thymoma.
The effect of diclofenac on proliferation and production of growth factors by endothelial cells (HMEC-1) under hypoxia and inflammatory conditions.
New
Wiktorowska-Owczarek, In Acta Pharm, 01 Apr 2014
HMEC-1 cells were treated with 0.1 and 0.3 mmol L-1 diclofenac in the presence of 100 μg mL-1 LPS or 200 μmol L-1 CoCl2.
Spectrofluorimetric determination of gemifloxacin mesylate and linezolid in pharmaceutical formulations: Application of quinone-based fluorophores and enhanced native fluorescence.
New
Fawzy et al., In Acta Pharm, 01 Apr 2014
Linearity was obtained over concentration ranges 50-500, 10-60 and 20-400 ng mL-1 for methods A, B and C, respectively.
Degradation of soil cyanide by single and mixed cultures of Pseudomonas stutzeri and Bacillus subtilis.
New
Dibua et al., In Arh Hig Rada Toksikol, 01 Apr 2014
The bacteria Pseudomonas stutzeri and Bacillus subtilis were selected based on their good growth in a minimal medium containing 0.8 mg mL-1 potassium cyanide (KCN).
Role of TH17 cytokines in the control of colorectal cancer.
Review
New
Stolfi et al., Roma, Italy. In Oncoimmunology, Jan 2014
Studies with murine models of CRC have delineated the mechanisms by which TH17 cytokines, notably, interleukin (IL)-17A, IL-17F, IL-21, and IL-22, regulate oncogenesis and tumor progression, paving the way to the development of novel anticancer drugs.
The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae.
New
Makiela et al., Rockhampton, Australia. In Toxins (basel), Dec 2013
Under laboratory conditions, Bufo marinus larvae were exposed to 100,000 cells mL-1 of Limnothrix (strain AC0243) live cultures for seven days.
Unravelling the Complex Antimicrobial Interactions of Essential Oils - The Case of Thymus vulgaris (Thyme).
New
Viljoen et al., Pretoria, South Africa. In Molecules, Dec 2013
Based on their minimum inhibitory concentration (MIC) values, they were categorised into weak (≥4 mg mL-1), moderate (2-4 mg mL-1) and noteworthy active (≤2 mg mL-1) compounds.
An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
New
Impact
Casanova et al., New York City, United States. In Immunity, Nov 2013
Patients with inborn errors of interleukin-17F (IL-17F) or IL-17RA display chronic mucocutaneous candidiasis (CMC).
Roles of T helper 17 cells and interleukin-17 in neuroautoimmune diseases with emphasis on multiple sclerosis and Guillain-Barré syndrome as well as their animal models.
Review
New
Zhu et al., Changchun, China. In J Neurosci Res, Jul 2013
Among the Th17-related effector cytokines, such as IL-17, IL-17F, IL-21, and IL-22, IL-17 is regarded as a key cytokine to induce inflammatory responses.
Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.
New
Impact
Rawlings et al., Córdoba, Argentina. In Nat Immunol, May 2013
With both mouse and human primary B cells, we found that exposure to parasite-derived trans-sialidase in vitro was sufficient to trigger modification of the cell-surface mucin CD45, which led to signaling dependent on the kinase Btk and production of IL-17A or IL-17F via a transcriptional program independent of the transcription factors RORγt and Ahr.
Effect of IL-17A blockade with secukinumab in autoimmune diseases.
Review
New
Antoni et al., Basel, Switzerland. In Ann Rheum Dis, Apr 2013
Th17 cells are known to produce the proinflammatory cytokine IL-17A as well as other effector cytokines, including IL-17F and IL-22.
Essentials of Th17 cell commitment and plasticity.
Review
New
Restifo et al., Bethesda, United States. In Blood, Apr 2013
Th17 cells express the master transcriptional regulator retinoic acid-related orphan receptor γ thymus and produce canonical interleukin (IL)-17A and IL-17F cytokines.
The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses.
New
Impact
Baier et al., Innsbruck, Austria. In Immunity, Feb 2013
Consistently, Prkca(-/-) cells failed to mount appropriate IL-17A, but not IL-17F, responses in vitro and were resistant to induction of Th17-cell-dependent experimental autoimmune encephalomyelitis in vivo.
Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases.
Review
Yoshimoto et al., Tokyo, Japan. In Clin Dev Immunol, 2012
T-helper 17 (Th17) cells are characterized by producing interleukin-17 (IL-17, also called IL-17A), IL-17F, IL-21, and IL-22 and potentially TNF- α and IL-6 upon certain stimulation.
The IL6 gene polymorphism -634C>G and IL17F gene polymorphism 7488T>C influence bone mineral density in young and elderly Japanese women.
GeneRIF
Fuke et al., Hachiōji, Japan. In Gene, 2012
IL17F gene polymorphism 7488T>C influences bone mineral density.
Interleukin-33 induces interleukin-17F in bronchial epithelial cells.
GeneRIF
Hizawa et al., Tsukuba, Japan. In Allergy, 2012
data suggest that the IL-33/IL-17F axis is involved in allergic airway inflammation
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction.
Impact
Sheppard et al., San Francisco, United States. In Nat Med, 2012
Interleukin-17A (IL-17A), but not IL-17F or IL-22, enhanced contractile force generation of airway smooth muscle through an IL-17 receptor A (IL-17RA)-IL-17RC, nuclear factor κ light-chain enhancer of activated B cells (NF-κB)-ras homolog gene family, member A (RhoA)-Rho-associated coiled-coil containing protein kinase 2 (ROCK2) signaling cascade.
Association analysis of IL-17A and IL-17F polymorphisms in Chinese Han women with breast cancer.
GeneRIF
Pang et al., Harbin, China. In Plos One, 2011
Results suggested that single-nucleotide polymorphisms (SNPs) in IL-17A but not IL-17F were associated with the risk of breast cancer.
A protective role by interleukin-17F in colon tumorigenesis.
GeneRIF
Dong et al., Wuhan, China. In Plos One, 2011
Together, our findings demonstrate a protective role for IL-17F in colon cancer development, possibly via inhibiting tumor angiogenesis
[Dynamics of serum IL-17A, IL-17F and IL-23 in patients with inflammatory bowel disease].
GeneRIF
Efremov et al., In Eksp Klin Gastroenterol, 2010
Dynamics of serum IL-17A, IL-17F and IL-23 in patients with inflammatory bowel disease
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