Papers on
MIP-2
SN50, a Cell-Permeable-Inhibitor of Nuclear Factor-κB, Attenuates Ventilator-Induced Lung Injury in an Isolated and Perfused Rat Lung Model.Tsai et al., Taipei, Taiwan. In Shock, Feb 2016
VILI was demonstrated by increased pulmonary vascular permeability and lung weight gain, as well as by increased levels of interleukin (IL)-1β, tumor necrosis factor (TNF)-α, myeloperoxidase, hydrogen peroxide, and macrophage inflammatory protein-2 in the bronchoalveolar lavage fluid.
CD26/dipeptidylpeptidase IV-chemokine interactions: double-edged regulation of inflammation and tumor biology.Struyf et al., Leuven, Belgium. In J Leukoc Biol, Feb 2016
A large number of human chemokines, including CXCL2, CXCL6, CXCL9, CXCL10, CXCL11, CXCL12, CCL3L1, CCL4, CCL5, CCL11, CCL14, and CCL22, are cleaved by CD26; however, the efficiency is clearly influenced by the amino acids surrounding the cleavage site and although not yet proven, potentially affected by the chemokine concentration and interactions with third molecules.
Role of chitinase-like proteins in cancer.Mitrofanova et al., In Biol Chem, Feb 2016
YKL-40 supports tumor angiogenesis by interaction with syndecan-1 on endothelial cells and metastatic spread by stimulating production of pro-inflammatory and pro-invasive factors MMP9, CCL2 and CXCL2.
CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection.Worthen et al., Philadelphia, United States. In Immunity, 2010
CXCL5 increased the plasma concentrations of CXCL1 and CXCL2 in part through inhibiting chemokine scavenging, impairing chemokine gradients and desensitizing CXCR2, which led to decreased neutrophil influx to the lung, increased lung bacterial burden and mortality in an Escherichia coli pneumonia model.