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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Metastasis suppressor 1

Mima, Metastasis suppressor, MTSS1
Top mentioned proteins: CAN, Actin, miR, HAD, V1a
Papers on Mima
Inhibition of miR-15b decreases cell migration and metastasis in colorectal cancer.
Ren et al., Changsha, China. In Tumour Biol, Feb 2016
Metastasis suppressor-1 (MTSS1) and Klotho protein expression were detected by Western blot and immunohistochemistry. Invasion and migration of CRC tumor cells were measured by transwell plates.
Cyclin-dependent kinase-mediated phosphorylation of breast cancer metastasis suppressor 1 (BRMS1) affects cell migration.
Šarčević et al., Australia. In Cell Cycle, Feb 2016
Expression of Breast Cancer Metastasis Suppressor 1 (BRMS1) reduces the incidence of metastasis in many human cancers, without affecting tumorigenesis.
In vitro biophysical, microspectroscopic and cytotoxic evaluation of metastatic and non-metastatic cancer cells in responses to anti-cancer drug.
Zhou et al., Logan, United States. In Anal Methods, Jan 2016
UNASSIGNED: The Breast Cancer Metastasis Suppressor 1 (BRMS1) is a nucleo-cytoplasmic protein that suppresses cancer metastasis without affecting the growth of the primary tumor.
MTSS1 is a critical epigenetically regulated tumor suppressor in CML.
Koschmieder et al., Aachen, Germany. In Leukemia, Jan 2016
We have identified Metastasis suppressor 1 (Mtss1/MIM) to be downregulated in hematopoietic stem and progenitor cells from leukemic transgenic SCLtTA/Bcr-Abl mice and in patients with CML at diagnosis, and Mtss1 was restored when patients achieved complete remission.
Regulation of the metastasis suppressor Nm23-H1 by tumor viruses.
Robertson et al., Philadelphia, United States. In Naunyn Schmiedebergs Arch Pharmacol, Feb 2015
Metastasis suppressor genes (MSGs) are promising targets for inhibition of the metastasis process.
MTSS1 gene regulated by miR-96 inhibits cell proliferation and metastasis in tongue squamous cellular carcinoma Tca8113 cell line.
Zhong et al., Shenyang, China. In Int J Clin Exp Med, 2014
BACKGROUND: Metastasis suppressor-1 (MTSS1) is a novel potential metastasis suppressor gene in several types of human cancers.
Design of small molecules targeting I-BAR proteins.
Gu et al., Nanjing, China. In Curr Pharm Des, 2014
Missing in metastasis (MIM, also MTSS1) is a member of the inverse Bin-Amphiphysin-Rvs (I-BAR) family that senses and stabilizes negative membrane protrusions.
Comparative analysis of blood and saliva expression profiles in chronic and refractory periodontitis patients.
He et al., Wuhan, China. In Bmc Oral Health, 2014
In addition, CD24, EST1, MTSS1, ING3, CCND2 and SYNE2 might be potential targets for diagnosis and treatment of CP.
MTSS1 is an independent prognostic biomarker for survival in intrahepatic cholangiocarcinoma patients.
Zhang et al., Shanghai, China. In Am J Transl Res, 2014
MTSS1 is a possible metastasis suppressor which has been proved to play a key role in metastasis of various tumors, yet its role in intrahepatic cholangiocarcinoma (ICC) remains unclear.
Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors.
Richardson et al., Shanghai, China. In Carcinogenesis, 2013
The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), is negatively correlated with tumor progression in multiple neoplasms, being a promising new target for cancer treatment.
Metastasis suppressor genes.
Huang et al., Seattle, United States. In Histol Histopathol, 2013
Metastasis is a complex process that requires the regulation of both metastasis-promoting and metastasis suppressor genes.
Mechanisms of Metastatic Tumor Dormancy.
Keller et al., Ann Arbor, United States. In J Clin Med, 2012
This period of dormancy is induced and maintained by several mechanisms, including: (1) Tumor microenvironment factors such as cytokine expression, immunosurveillance and angiogenesis; (2) Metastasis suppressor gene activity; and (3) Cancer therapeutics.
Dimerization is necessary for MIM-mediated membrane deformation and endocytosis.
Zhan et al., Nanjing, China. In Biochem J, 2012
the dimeric configuration is essential for MIM-mediated membrane remodelling and serves as a proper target to develop antagonists specifically against an I-BAR-domain-containing protein.
Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells.
Machesky et al., Glasgow, United Kingdom. In Oncogene, 2012
at high cell densities, Mtss1 impacts negatively on EGF signaling and this suggests why it inhibits metastasis.
Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.
Machesky et al., Glasgow, United Kingdom. In Plos One, 2011
Data show that Mtss1 drives enhanced junction formation specifically by elevating Rac-GTP.
cAMP signaling by anthrax edema toxin induces transendothelial cell tunnels, which are resealed by MIM via Arp2/3-driven actin polymerization.
Lemichez et al., Nice, France. In Cell Host Microbe, 2011
Anthrax edema toxin induced transendothelial cell tunnels are resealed by MIM via Arp2/3-driven actin polymerization.
Metastasis suppressor-1, MTSS1, acts as a putative tumour suppressor in human bladder cancer.
Jiang et al., Cardiff, United Kingdom. In Anticancer Res, 2011
MTSS1 is expressed at low levels or is absent from human bladder cancer cells.
Learning therapeutic lessons from metastasis suppressor proteins.
Theodorescu et al., Charlottesville, United States. In Nat Rev Cancer, 2009
Metastasis suppressor proteins regulate multiple steps in the metastatic cascade, including cancer cell invasion, survival in the vascular and lymphatic circulation, and colonization of distant organ sites.
In situ multi-satellite detection of coherent vortices as a manifestation of Alfvénic turbulence.
Rème et al., Orléans, France. In Nature, 2005
Vortex motion in fluids and magnetized plasmas is typically governed by nonlinear equations, examples of which include the Navier-Stokes equation, the Charney-Hasegawa-Mima equations and their numerous generalizations.
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor.
Fujino et al., Tsukuba, Japan. In Nature, 2001
KiSS-1 is a human metastasis suppressor gene, that suppresses metastases of human melanomas and breast carcinomas without affecting tumorigenicity.
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