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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

MICAL-like 1

MICAL-L1
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Top mentioned proteins: Rab5, Eps15, CAN, ARF6, EHD2
Papers on MICAL-L1
The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking.
New
Niedergang et al., Paris, France. In J Cell Biol, Nov 2015
We showed that maturation arrest occurred at the level of the EHD3/MICAL-L1 endosomal sorting machinery.
Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.
Caplan et al., Omaha, United States. In Traffic, 2015
We have previously demonstrated that Molecule Interacting with CasL Like-1 (MICAL-L1) and C-terminal Eps15 Homology Domain protein 1 (EHD1) coordinately regulate receptor transport from tubular recycling endosomes during interphase.
MICAL-L1-related and unrelated mechanisms underlying elongated tubular endosomal network (ETEN) in human dendritic cells.
Boes et al., Utrecht, Netherlands. In Commun Integr Biol, 2014
Using a knock-down approach we demonstrate that MICAL-L1 is necessary for ETEN remodeling originating from ERC in human DCs.
Role of the EHD2 unstructured loop in dimerization, protein binding and subcellular localization.
Caplan et al., Omaha, United States. In Plos One, 2014
Indeed, the EHD1 RPF motif was required for dimerization, interaction with MICAL-L1 and Syndapin2, as well as localization to tubular recycling endosomes.
Diacylglycerol kinase α regulates tubular recycling endosome biogenesis and major histocompatibility complex class I recycling.
Caplan et al., Omaha, United States. In J Biol Chem, 2014
Moreover, we show that DGKα forms a complex with the TRE hub protein, MICAL-L1.
Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1.
Caplan et al., Omaha, United States. In J Cell Sci, 2014
Here, we demonstrate that Src partially colocalizes with the endocytic regulatory protein MICAL-L1 (molecule interacting with CasL-like protein 1) in mammalian cells.
Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth.
Fukuda et al., Sendai, Japan. In Biol Open, 2013
We previously showed that active Rab35 promotes nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells by recruiting MICAL-L1, a multiple Rab-binding protein, to Arf6-positive recycling endosomes.
GRAF1 forms a complex with MICAL-L1 and EHD1 to cooperate in tubular recycling endosome vesiculation.
Naslavsky et al., Omaha, United States. In Front Cell Dev Biol, 2013
In the present study, we identify the GTPase Regulator Associated with Focal adhesion kinase-1 (GRAF1) protein in a complex with EHD1 and the TRE hub protein, Molecules Interacting with CasL-Like1 (MICAL-L1).
MICAL-like1 in endosomal signaling.
Zahraoui, Paris, France. In Methods Enzymol, 2013
Using yeast two-hybrid screen, we identified MICAL-like1 (MICAL-L1), a protein that interacts with GTP-bound Rab13 and shares a similar domain organization with MICAL protein family.
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Caplan et al., Omaha, United States. In J Biol Chem, 2013
We developed a novel semipermeabilized cell system in which addition of purified EHD proteins to reconstitute vesiculation allows us to assess the ability of each protein to vesiculate MICAL-L1-decorated tubular recycling endosomes (TREs).
Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
Fukuda et al., Sendai, Japan. In J Cell Sci, 2013
Rab35 forms a tripartite complex with MICAL-L1 and centaurin-β2/ACAP2 and recruits them to perinuclear Arf6-positive endosomes in response to nerve growth factor stimulation.
Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.
Caplan et al., Omaha, United States. In Mol Biol Cell, 2013
However, recent studies show that molecules interacting with CasL-Like1 (MICAL-L1), a second, recently identified RE tubule marker, recruits EHD1 to preexisting tubules.
Trafficking cascades mediated by Rab35 and its membrane hub effector, MICAL-L1.
Caplan et al., Omaha, United States. In Commun Integr Biol, 2012
Recent studies point to the protein MICAL-L1 as a major scaffold for these regulators.
Differential regulation of actin microfilaments by human MICAL proteins.
Caplan et al., Omaha, United States. In J Cell Sci, 2012
In mammalian cells there are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2, but little is known of their function, and information comes almost exclusively from neural cells.
MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.
GeneRIF
Caplan et al., Omaha, United States. In Traffic, 2012
Rab35 is a critical upstream regulator of MICAL-L1 and Arf6, while both MICAL-L1 and Arf6 regulate Rab8a function.
MICAL-like1 mediates epidermal growth factor receptor endocytosis.
GeneRIF
Zahraoui et al., Gif-sur-Yvette, France. In Mol Biol Cell, 2011
novel insights into the MICAL-L1/Rab protein complex that can regulate EGFR trafficking at late endocytic pathways.
MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.
GeneRIF
Caplan et al., Omaha, United States. In Mol Biol Cell, 2009
These data implicate MICAL-L1 as an unusual type of Rab effector that regulates endocytic recycling by recruiting and linking EHD1 and Rab8a on membrane tubules.
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