[An immunological approach to acute myeloid leukaemia].
Madrid, Spain. In An Pediatr (barc), Dec 2015
The mean fluorescence intensities of HLA-I, MICA/B and ULBP1-4, ligands for NK cell receptors, were also analysed in ten new diagnosed leukaemia cases, five myeloid and five lymphoid.
The immunogenetics of Psoriasis: A comprehensive review.
New York City, United States. In J Autoimmun, Nov 2015
These genes span an array of functions that involve antigen presentation (HLA-Cw6, ERAP1, ERAP2, MICA), the IL-23 axis (IL12Bp40, IL23Ap19, IL23R, JAK2, TYK2), T-cell development and T-cells polarization (RUNX1, RUNX3, STAT3, TAGAP, IL4, IL13), innate immunity (CARD14, c-REL, TRAF3IP2, DDX58, IFIH1), and negative regulators of immune responses (TNIP1, TNFAIP3, NFKBIA, ZC3H12C, IL36RN, SOCS1).
Regulated Control of the Assembly and Diversity of LPS by Noncoding sRNAs.
Gdańsk, Poland. In Biomed Res Int, 2014
LPS composition is highly heterogeneous and dynamically altered upon stress and other challenges in the environment because of the transcriptional activation of RpoE regulon members and posttranslational control by RpoE-regulated Hfq-dependent RybB and MicA sRNAs.
Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands.
Seattle, United States. In Nature, 2007
However, many progressing tumours in humans counter this anti-tumour activity by shedding the soluble major histocompatibility complex class-I-related ligand MICA, which induces internalization and degradation of NKG2D and stimulates population expansions of normally rare NKG2D+CD4+ T cells with negative regulatory functions.