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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Mindbomb homolog 2

Mib2, SKD, mind bomb-2, Skeletrophin
Top mentioned proteins: Ubiquitin, MIB-1, GDNF, AGE, ACID
Papers using Mib2 antibodies
Drosophila mind bomb2 is required for maintaining muscle integrity and survival
Frasch Manfred et al., In The Journal of Cell Biology, 1996
... UAS-mib2ΔRF transgenic lines, we subcloned the ...
Papers on Mib2
Spleen-specific isoforms of Pax5 and Ataxin-7 as potential proteomic markers of lymphoma-affected spleen.
Mishra et al., Benares, India. In Mol Cell Biochem, Apr 2015
Simultaneously, lower levels of SOD, NDR2, and MIB2 and higher expression levels of Ataxin-7 and LDH also suggest impact of stress either as a cause or effect of cell proliferation.
The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling.
Ashworth et al., Newcastle upon Tyne, United Kingdom. In Oncotarget, 2015
To dissect CYLD function we used a proteomics approach to identify CYLD interacting proteins and identified MIB2, an ubiquitin ligase enzyme involved in Notch signalling, as a protein which interacts with CYLD.
Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish.
Itoh et al., Chiba, Japan. In Biol Open, 2014
The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share specific substrates.
Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein.
Joo et al., Seoul, South Korea. In J Virol, 2014
Pulldown experiments using wild-type and mutant MAVS showed that mindbomb E3 ubiquitin protein ligase 2 (MIB2) binds to the DLAIS motif.
Suitability of spring wheat varieties for the production of best quality pizza.
Saeed et al., Faisalābād, Pakistan. In J Food Sci Technol, 2014
Furthermore, pizza prepared from respective flour samples were further evaluated for sensory attributes Results showed that Anmool, Abadgar, Imdad, SKD-1, Shafaq and Moomal have higher values for protein, gluten content, pelshenke value and SDS sedimentation and these were relatively better in studied parameters as compared to other varieties although which were considered best for good quality pizza production.
Differential processing of mammalian L-histidine decarboxylase enzymes.
Fleming et al., Cork, Ireland. In Biochem Biophys Res Commun, 2014
Instead we identified SKD and EEAPD motifs that are important for caspase-6 dependent production of ~54 and ~59 kDa isoforms in the rat and human proteins, respectively.
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation.
Farnham et al., Davis, United States. In Nucleic Acids Res, 2013
We have created six-finger ATFs to target two different 18 nt regions of the human SOX2 promoter; each ATF is constructed such that it contains or lacks a super KRAB domain (SKD) that interacts with a complex containing repressive histone methyltransferases.
The first patient with a pure 1p36 microtriplication associated with severe clinical phenotypes.
Tan et al., Changsha, China. In Mol Cytogenet, 2013
The expression levels of B3GALT6, MIB2, PEX10 and PANK4 in the blood were determined, and differential expressions were observed between the patients and controls.
Towards sustained silencing of HER2/neu in cancer by epigenetic editing.
Rots et al., Groningen, Netherlands. In Mol Cancer Res, 2013
HER2/neu-overexpressing cancer cells were transduced to express a zinc finger protein (ZFP), targeting the HER2/neugene, fused to histone methyltransferases (G9a, SUV39-H1)/super KRAB domain (SKD).
ASN540SER mutation is associated with a mild form of hypochondroplasia: a 7 years follow-up in an Italian boy.
Zucchini et al., Ferrara, Italy. In Georgian Med News, 2012
Skeletal dysplasias (SKD) are genetic disorders that result in the abnormal development of part or all of the skeleton and are commonly associated with short stature.
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer.
Blancafort et al., Groningen, Netherlands. In Nucleic Acids Res, 2012
The 6ZF domains were linked to the Kruppel Associated Box (SKD) repressor domain.
Relationship between Obesity-related Hormone Peptides and Quality of Life in Obese Women among Different Traditional Chinese Medicine Syndrome Groups.
Hsu et al., Taipei, Taiwan. In J Tradit Complement Med, 2012
According to the responses provided, the obese subjects were classified into spleen deficiency with dampness encumbrance syndrome ( pí xū shī zǔ zhèng; SDD), stomach heat with dampness encumbrance syndrome ( wèi rè shī zǔ zhèng; SHD), liver depression and qi stagnation syndrome ( gān yù qì zhì zhèng; LDQ), dual spleen-kidney deficiency syndrome ( pí shèn liǎng xū zhèng; SKD), yin deficiency with internal heat syndrome ( yīn xū nèi rè zhèng; YDI) and a control group.
The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation.
Redecke et al., Memphis, United States. In J Biol Chem, 2011
identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway.
Mind bomb 2, a founder myoblast-specific protein, regulates myoblast fusion and muscle stability.
Ruiz-Gómez et al., Madrid, Spain. In Development, 2008
Here we characterise Mind bomb 2 (Mib2), a protein with putative E3 ubiquitin ligase activity that is exclusive of FMs and necessary for at least two distinct steps of the founder/myotube differentiation programme.
Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.
Ron et al., San Francisco, United States. In J Biol Chem, 2008
Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells.
Targeted disruption of Mib2 causes exencephaly with a variable penetrance.
Artzt et al., In Genesis, 2007
created a targeted mutation of Mib2 and show that its phenotype is a variable penetrance, failure to close the cranial neural tube
Drosophila mind bomb2 is required for maintaining muscle integrity and survival.
Frasch et al., United States. In J Cell Biol, 2007
We report that the Drosophila mind bomb2 (mib2) gene is a novel regulator of muscle development.
The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly.
Jiang et al., Singapore, Singapore. In Dev Biol, 2007
Zebrafish Mib and Mib2 are colocalized in transfected cells and function redundantly in regulating Notch signaling in embryos.
A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.
Ohtsuki et al., Kōchi, Japan. In Oncogene, 2006
skeletrophin might be a novel suppressor factor for melanoma invasion
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