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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Mindbomb homolog 1

MIB-1
Top mentioned proteins: HAD, p53, AGE, CAN, fibrillin-1
Papers using MIB-1 antibodies
Prognostic value of androgen receptor expression in operable triple-negative breast cancer: a retrospective analysis based on a tissue microarray
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Lazutka Juozas et al., In Diagnostic Pathology, 2010
... BCL2, SATB1 and HIF-1α was performed using the SP1, 1E2 and 4B5 (Ventana), SP107 (Spring), MIB-1 (DAKO), DO-7 (Novocastra), E6H4 (CINtec), ...
Identification of subtypes in human epidermal growth factor receptor 2--positive breast cancer reveals a gene signature prognostic of outcome
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Serrano María José et al., In Breast Cancer Research : BCR, 2009
... Ki-67 proliferation index was assessed by using mouse monoclonal antibody MIB-1 (1:200 dilutions; Dako, Glostrup, Denmark), and the ...
Primary Malignant Giant-Cell Tumor of Bone Has High Survival Rate
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Gitelis Steven et al., In Diagnostic Pathology, 2009
... Ki-67 immunostaining was performed on the Dako autostainer PLUS with FLEX Envision chemistry using clone MIB-1 (Dako, Carpentaria, CA), at 1:400 ...
ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receoptor, progesterone receptor, and Ki-67.
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van Diest Paul, In PLoS ONE, 2009
... were immunostained with MIB-1 according to standard protocols (DAKO M7240, 1∶20) using the ...
Quantifying the role of aberrant somatic hypermutation in transformation of follicular lymphoma
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Delabie Jan et al., In Journal of Hematopathology, 2007
... Ki67 (MIB-1)DAKO Cytomation, Denmark A/S ...
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Papers on MIB-1
Silent subtype 3 pituitary adenomas are not always silent and represent poorly differentiated monomorphous plurihormonal Pit-1 lineage adenomas.
New
Asa et al., Toronto, Canada. In Mod Pathol, Feb 2016
The mean MIB-1 labeling index was 4% (range, 1-9%).
WNT/β-catenin Signaling Pathway and Downstream Modulators in Low- and High-grade Glioma.
New
Schiffer et al., Torino, Italy. In Cancer Genomics Proteomics, Feb 2016
TCF4 was statistically correlated with Ki-67/MIB-1 and cyclin D1 labeling indices.
Pancreatic hamartoma: a case report and literature review.
New
Natsugoe et al., Kagoshima, Japan. In Bmc Gastroenterol, Dec 2015
Adipose tissue showed positive staining for S-100 protein and there were only a few MIB-1 positive cells.
The Prognostic Role of Ki-67/MIB-1 in Upper Urinary-Tract Urothelial Carcinomas: A Systematic Review and Meta-Analysis.
Review
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Chen et al., Changsha, China. In J Endourol, Nov 2015
One biomarker-Ki-67/mindbomb E3 ubiquitin protein ligase 1 (Ki-67/MIB-1)-shows promise in UTUC, but there have been conflicting findings regarding its prognostic role.
Microcystic/Reticular Schwannoma of the Mandible First Case Report and Review of the Literature.
Review
New
Wu et al., Shanghai, China. In Medicine (baltimore), Nov 2015
The proliferation marker MIB-1 showed <1% nuclear reaction.
Adult granulosa cell tumor of the testis masquerading as hydrocele.
New
Ray et al., New Delhi, India. In Int Braz J Urol, Nov 2015
Role of MIB-1 labelling index in prognostication is not well defined.
Hot-spot selection and evaluation methods for whole slice images of meningiomas and oligodendrogliomas.
New
Slodkowska et al., In Conf Proc Ieee Eng Med Biol Soc, Aug 2015
The studied slides represent the meningiomas and oligodendrogliomas tumor on the basis of the Ki-67/MIB-1 immunohistochemical reaction.
Correlation and discordance of tumour proliferation index and molecular imaging characteristics and their implications for treatment decisions and outcome pertaining to peptide receptor radionuclide therapy in patients with advanced neuroendocrine tumour: developing a personalized model.
Review
New
Thapa et al., Mumbai, India. In Nucl Med Commun, Aug 2015
This communication critically illustrates the molecular imaging features and correlates them with the histopathological characteristics (focussing primarily on Ki-67 or MiB1 index) of neuroendocrine tumours (NETs), their implications for important treatment decision-making, and their response to peptide receptor radionuclide therapy.
Ki-67/MIB-1 as a Prognostic Marker in Cervical Cancer - a Systematic Review with Meta-Analysis.
Review
Naghavi-Behzad et al., Tabrīz, Iran. In Asian Pac J Cancer Prev, 2014
BACKGROUND: In cervical cancer patients it has been reported that there in a significant Ki-67/MIB-1 expression is correlated with survival in cervical cancer patients.
Histiocytic Sarcoma Originating in the Lung in a 16-Year-Old Male.
Review
Nakamura et al., Funaishikawa, Japan. In J Clin Exp Hematop, 2014
The tumor cells were immunohistochemically positive for CD68 and CD163, indicating histiocytic lineage and the MIB-1-positive rate was low.
Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.
Impact
de la Pompa et al., Madrid, Spain. In Nat Med, 2013
We show that germline mutations in human MIB1 (mindbomb homolog 1), which encodes an E3 ubiquitin ligase that promotes endocytosis of the NOTCH ligands DELTA and JAGGED, cause LVNC in autosomal-dominant pedigrees, with affected individuals showing reduced NOTCH1 activity and reduced expression of target genes.
Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas.
GeneRIF
Pollack et al., Lexington, United States. In Neuro Oncol, 2012
High MIB1 proliferation index trended toward worse response to adjuvant radiotherapy in gliomas.
Mind bomb 1 is required for pancreatic β-cell formation.
GeneRIF
Jensen et al., Denmark. In Proc Natl Acad Sci U S A, 2012
Data show that Mind bomb 1 (Mib1) is required for correct proximodistal (P-D) patterning of the developing pancreas and beta-cell formation.
The E3 ubiquitin ligase MIB1 negatively regulates basal IκBα level and modulates NF-κB activation.
GeneRIF
Wang et al., In Cell Res, 2012
MIB1 negatively regulates TNFalpha- and IL1beta-induced NF-kappaB target gene activation
Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation.
GeneRIF
Kong et al., Seoul, South Korea. In Plos One, 2011
Mib1 in dendritic cells is critical for the activation of Notch signaling in CD4(+) T cells
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.
GeneRIF
Moon et al., Seattle, United States. In J Cell Biol, 2011
RYK interacts both physically and functionally with the E3 ubiquitin MIB1. MIB1 is sufficient to activate Wnt/CTNNB1 signaling and this activity depends on endogenous RYK.
Y-box-binding protein YB-1 identifies high-risk patients with primary breast cancer benefiting from rapidly cycled tandem high-dose adjuvant chemotherapy.
Impact
Harbeck et al., Köln, Germany. In J Clin Oncol, 2010
High YB-1 was associated with aggressive tumor phenotype (negative steroid hormone receptor status, positive human epidermal growth factor receptor 2 and p53 status, high MIB-1, unfavorable tumor grade) and poor OS (median 78 v 97 months; P = .01).
Phase II study of dose-adjusted EPOCH and rituximab in untreated diffuse large B-cell lymphoma with analysis of germinal center and post-germinal center biomarkers.
Impact
Janik et al., Bethesda, United States. In J Clin Oncol, 2008
PURPOSE: To assess the clinical outcome and the influence of biomarkers associated with apoptosis inhibition (Bcl-2), tumor proliferation (MIB-1), and cellular differentiation on the outcome with dose-adjusted (DA) EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin) plus rituximab (R) infusional therapy in diffuse large B-cell lymphoma (DLBCL) with analysis of germinal center B-cell (GCB) and post-GCB subtypes by immunohistochemistry. PATIENTS AND METHODS: Phase II study of 72 patients with untreated de novo DLBCL who were at least 18 years of age and stage II or higher.
Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications--a study from the Lunenburg Lymphoma Biomarker Consortium.
Impact
Lunenburg Lymphoma Biomarker Consortium et al., Amsterdam, Netherlands. In J Clin Oncol, 2007
PATIENTS AND METHODS: Sections of a tissue microarray from 36 patients with DLBCL were stained in eight laboratories with antibodies to CD20, CD5, bcl-2, bcl-6, CD10, HLA-DR, MUM1, and MIB-1 according to local methods.
Biologic and prognostic significance of dermal Ki67 expression, mitoses, and tumorigenicity in thin invasive cutaneous melanoma.
Impact
Guerry et al., Philadelphia, United States. In J Clin Oncol, 2005
PATIENTS AND METHODS: We used immunohistochemistry to determine Ki67 expression using the monoclonal antibody MIB-1 in lesions from a prospective cohort that included 396 patients with thin invasive primary melanomas seen between 1972 and 1991.
More papers using MIB-1 antibodies
Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors
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Langer Seppo W. et al., In The Scientific World Journal, 2006
... The Ki-67 index was determined immunohistochemically by applying a monoclonal mouse anti-human Ki-67 antigen (DAKO Clone MIB-1, Dako Denmark A/S, Glostrup, Denmark), ...
Utility of SKP2 and MIB-1 in grading follicular lymphoma using quantitative imaging analysis
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Dreyling Martin et al., In Journal of Hematopathology, 2006
...  = 10, Mib-1 antibody, alkaline phosphatase–antialkaline phosphatase method; Dako, Glostrup, Denmark), Kiel ( ...
Follicular dendritic cell sarcoma in the lymph nodes of the neck
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Adam Patrick et al., In Diagnostic Pathology, 2006
... Mib1DAKO ...
Mitosis-independent Survivin gene expression in vivo and regulation by p53
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Sverdlov E D et al., In British Journal of Cancer, 2005
... Danvers, MA, USA), mouse monoclonal anti-Bcl-2 (Upstate, Lake Placid, NY, USA), mouse monoclonal anti-Ki67 (clone MIB-1) and rabbit polyclonal Z0622 anti-pancytokeratin from Dako (Dako, Carpinteria, CA, USA) ...
Selenium binding protein 1 in ovarian cancer
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Lawrence W Dwayne et al., In Diagnostic Pathology, 2005
... index relative to SELENBP1 expression, the proliferation index was determined in sections of leiomyomas using MIB-1 antibody to the Ki67 antigen (Dako, Carpinteria, CA) ...
Oropharyngeal cancer pathogenesis: ubiquitin proteolytic, apoptotic and epidermal growth factor related pathways act in concert-first report
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Aguiar Maria C.F. et al., In Medicina Oral, Patología Oral y Cirugía Bucal, 2004
... antigens were performed using 31G7 monoclonal antibody clones (Zymed Laboratories Inc., San Francisco, CA, UK), MIB-1 (Dako, Carpinteria, USA), and SX5368 ...
Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice
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Blokx Willeke A. M. et al., In Acta Neuropathologica, 2003
... Dako Co., Lot 00060051), Melan-A (Mart-1, 1:800, Neomarkers, Lot 799P807C), HMB-45 (1:50, Neomarkers, Lot 23068), MIB-1 (Ki-67, 1:200, Dako Co., Lot 00045312), EMA ...
p53 in rheumatoid arthritis synovial fibroblasts at sites of invasion
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Mihatsch Michael J. et al., In Nephrology Dialysis Transplantation, 2002
... MIB-1/Ki671:1001DAKO, Glostrup, DK ...
Gastrointestinal stromal tumors: chemotherapy and imatinib
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K. Breuhahn et al., In Rare Tumors, 2001
... Abcam, Cambridge, UK), as well as CD31 (1:25, Dako) and MIB1 (1:200, Dako), using the EnVision™ system ...
De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients
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Stein Harald et al., In Virchows Archiv, 2001
... MIB-1Citrate1:2000Dako ...
Automated subcellular localization and quantification of protein expression in tissue microarrays
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Isola Jorma et al., In Breast Cancer Research : BCR, 2001
... antibody PgR636 (diluted 1:600, Leica Biosystems, Newcastle, UK), and Ki-67 was detected using monoclonal antibody MIB-1 (diluted 1:100, Dako, Carpinteria, CA, USA) ...
EGFR related peptides and their cognate receptors in breast cancer
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Thomas Shaji et al., In International Journal of Breast Cancer, 2000
... Immunohistochemistry for ki-67 Ki67 (MIB-1 clone) DAKO, mouse monoclonal antibody, dilution ...
Growth of incidental meningiomas
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Hori Tomokatsu et al., In Neurosurgical Review, 1999
An avidin-biotin immunoperoxidase or simple stain MAX-peroxidase (Nichirei, Tokyo) technique was used to perform MIB-1 monoclonal antibody (DAKO, Denmark) assay in selected ...
Hormonal regulation of apoptosis in breast cells and tissues
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Allred D Craig et al., In Breast Cancer Research, 1999
... The immunohistochemical assay used mouse monoclonal antibody MiB1 (Dako) against the Ki67 proliferation-associated ...
Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast
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Wu Anna H et al., In Breast Cancer Research, 1998
... A single slide was cut from each block and stained with the proliferation marker MIB1 (BioGenex Laboratories, San Ramon, CA, ...
Metallothionein expression in basaloid proliferations overlying dermatofibromas and basal cell carcinomas
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Szepietowski Jacek C. et al., In Pathology Oncology Research, 1996
... which binds specifically MT-I and MT-II, using a 1:100 dilution for MT and the monoclonal antibody MIB-1 (code M7240) diluted 1:50 for Ki-67 antigen (Dako, Denmark) ...
The complexities of proliferating cell nuclear antigen
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Torp Sverre H et al., In Diagnostic Pathology, 1991
... Ki-67/MIB-1Dako, Glostrup, DK ...
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