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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Integrin beta 1 binding protein 2

Melusin, ITGB1BP2
Top mentioned proteins: ACID, Akt, Hsp90, HAD, ERK
Papers on Melusin
The muscle-specific chaperone protein melusin is a potent cardioprotective agent.
Brancaccio et al., Torino, Italy. In Basic Res Cardiol, Mar 2015
Melusin is a protein selectively expressed in skeletal muscles and heart and highly conserved in vertebrates.
Overexpression of the muscle-specific protein, melusin, protects from cardiac ischemia/reperfusion injury.
Tarone et al., Orbassano, Italy. In Basic Res Cardiol, 2014
Melusin is a muscle-specific protein which interacts with β1 integrin cytoplasmic domain and acts as chaperone protein.
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction.
Hasenfuß et al., Göttingen, Germany. In Cardiovasc Res, 2014
AIMS: Melusin is a muscle-specific chaperone protein whose expression is required for a compensatory hypertrophy response to pressure overload.
Regulation of cardiac melusin gene expression by hypertrophic stimuli in the rat.
Rysä et al., Oulu, Finland. In Acta Physiol (oxf), 2013
AIM: Melusin is an integrin β1-interacting protein proposed to act as a biomechanical sensor in the heart.
Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy.
German Competence Network of Heart Failure et al., Marburg an der Lahn, Germany. In Gene, 2013
In a heterogeneous cohort of patients (n=255) with sporadic and familial dilated cardiomyopathy (DCM), we searched for novel disease-associated mutations in the human melusin-encoding ITGB1BP2 gene and found only one missense mutation, which was a substitution of alanine for glycine at position 313 located in the carboxy-terminal spacer region of the molecule.
Altered melusin pathways involved in cardiac remodeling following acute myocardial infarction.
Xu et al., Nanjing, China. In Cardiovasc Pathol, 2012
The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI.
Morgana and melusin: two fairies chaperoning signal transduction.
Brancaccio et al., Torino, Italy. In Cell Cycle, 2011
Here we describe morgana and melusin, two phylogenetically conserved chaperones that cooperate with Hsp90 and regulate signal transduction in important physiopathological processes.
ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1.
Tarone et al., Torino, Italy. In J Cell Sci, 2011
controls ERK1/2 activation in heart
Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure.
McMullen et al., Australia. In J Biol Chem, 2011
PI3K regulates the expression of genes essential for cardiac structure and Z-disc signaling, interacts with melusin, and is critical for Z-disc alignment
Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients.
Crovella et al., Torino, Italy. In Bmc Med Genet, 2008
Our analysis revealed an extremely low number of variations in the ITGB1BP2 gene in nearly 1000 hypertensive/cardiopathic and healthy individuals, thus suggesting a high degree of conservation of the melusin gene within the populations analyzed
The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.
Brancaccio et al., Torino, Italy. In Febs Lett, 2008
Melusin directly binds to Hsp90, a ubiquitous chaperone involved in regulating several signaling pathways.
Altered melusin expression in the hearts of aortic stenosis patients.
Regitz-Zagrosek et al., Berlin, Germany. In Eur J Heart Fail, 2007
BACKGROUND: The role of melusin, a necessary component in pressure-induced left-ventricular hypertrophy (LVH) in mice, has not yet been determined in human cardiac hypertrophy.
Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium.
Volders et al., Maastricht, Netherlands. In Am J Physiol Heart Circ Physiol, 2007
Repeated LV biopsies were analyzed for mRNA and/or protein expression of beta(1D)-integrin, melusin, Akt, GSK3beta, muscle LIM protein (MLP), four-and-a-half LIM protein 2 (fhl2), desmin, and calpain.
Chp-1 and melusin, two CHORD containing proteins in vertebrates.
Tarone et al., Torino, Italy. In Febs Lett, 2003
Melusin is a muscle specific protein required for heart hypertrophy in response to mechanical overload.
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload.
Lembo et al., Torino, Italy. In Nat Med, 2003
Data show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress.
Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain.
Silengo et al., Torino, Italy. In J Biol Chem, 1999
Here we describe the isolation and partial characterization of a new muscle-specific protein (Melusin) which interacts with the integrin cytoplasmic domain.
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