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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Mediterranean fever

MEFV
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, AGE, CAN, POLYMERASE, OUT
Papers on MEFV
Bone Mineral Density in Egyptian Children with Familial Mediterranean Fever.
New
Saad et al., Al Jīzah, Egypt. In Iran J Med Sci, Jan 2016
BACKGROUND: Familial Mediterranean fever (FMF) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (BMD).
Colchicine, Biologic Agents and More for the Treatment of Familial Mediterranean Fever. The Old, the New, and the Rare.
New
Portincasa, Bari, Italy. In Curr Med Chem, Dec 2015
Familial Mediterranean Fever (FMF) is a rare autosomal recessive autoinflammatory disorder involving the innate immunity and affecting almost exclusively populations with Mediterranean origin.
Frequency of mutations in Mediterranean fever gene, with gender and genotype-phenotype correlations in a Turkish population.
New
Bozkurt et al., Diyarbakır, Turkey. In J Genet, Dec 2015
Familial Mediterranean fever (FMF) is the most common hereditary inflammatory periodic disease, characterized by recurrent episodes of fever, abdominal pain, synovitis and pleurisy.
The immunogenetics of Behçet's disease: A comprehensive review.
Review
New
Remmers et al., Bethesda, United States. In J Autoimmun, Nov 2015
In addition, targeted next-generation sequencing has revealed the involvement of rare nonsynonymous variants of IL23R, TLR4, NOD2, and MEFV in Behçet's disease pathogenesis.
Patient with FMF and Triple MEFV Gene Mutations.
New
Fathi et al., Ardabīl, Iran. In Med Arh, Aug 2015
INTRODUCTION: Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease with monogenic (MEditerranean FeVer -MEFV- gene) inherited pattern.
The autoinflammatory diseases: a fashion with blurred boundaries!
Review
New
Touitou et al., Montpellier, France. In Semin Immunopathol, Jul 2015
Over 17 years have passed since the discovery of the first autoinflammatory gene, MEFV, responsible for familial Mediterranean fever.
The myths we believed in familial Mediterranean fever: what have we learned in the past years?
Review
New
Batu et al., Ankara, Turkey. In Semin Immunopathol, Jul 2015
Familial Mediterranean fever is the most common monogenic periodic fever syndrome over the world especially in the eastern Mediterranean.
Biological agents in familial Mediterranean fever focusing on colchicine resistance and amyloidosis.
Review
Kasapcopur et al., İstanbul, Turkey. In Curr Med Chem, 2014
Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory syndrome.
Relationship between clinical findings and genetic mutations in patients with familial Mediterranean fever.
Unuvar et al., İstanbul, Turkey. In Pediatr Rheumatol Online J, 2014
BACKGROUND: Familial Mediterranean fever (FMF) is one of the most frequent genetic diseases encountered in the Mediterranean region.
Killer Cell Immunoglobulin-Like Receptor (KIR) Genotype Distribution in Familial Mediterranean Fever (FMF) Patients.
Erken et al., Tokat, Turkey. In Med Sci Monit, 2014
BACKGROUND Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease predominantly affecting Mediterranean populations.
Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome.
Impact
Shao et al., Beijing, China. In Nature, 2014
Mutations in the Pyrin-encoding gene, MEFV, cause a human autoinflammatory disease known as familial Mediterranean fever.
Familial Mediterranean Fever.
Review
Karahan et al., Konya, Turkey. In Acta Medica (hradec Kralove), 2013
Familial Mediterranean Fever is an autosomal recessive inherited disease with a course of autoinflammation, which is characterized by the episodes of fever and serositis.
Significance of MEFV gene R202Q polymorphism in Turkish familial Mediterranean fever patients.
GeneRIF
Kisacik et al., Tokat, Turkey. In Gene, 2012
The genotype and allele frequencies of R202Q polymorphism showed a statistically significant difference between FMF patients and controls and especially the homozygous AA genotype was significantly higher in FMF patients than healthy controls.
The frequency of MEFV gene mutation in patients admitted to hospital with preliminary diagnosis of familian mediterranean fever who undergone a prior appendectomy.
GeneRIF
Yel et al., Diyarbakır, Turkey. In Eur Rev Med Pharmacol Sci, 2012
Report frequency of MEFV gene mutation in patients admitted to hospital with preliminary diagnosis of familian mediterranean fever who undergone a prior appendectomy.
MEFV gene mutations (M694V, V726A, M680I, and A744S) in Iranian children with Henoch-Schönlein purpura.
GeneRIF
Rad et al., Sārī, Iran. In Pneumologia, 2012
MEFV gene mutations are more frequent in Iranian Azeri Turkish children with Henoch-Schonlein Purpura (HSP) & it may be regarded as a genetic test for the diagnosis of HSP in Iranian Azeri Turkish patients.
Mediterranean fever gene mutations in Greek patients with Behcet's disease.
GeneRIF
Vaiopoulos et al., Athens, Greece. In West Indian Med J, 2012
Pyrin gene mutations in Greek patients with Behcet's disease are not more common than those in the general population.
Three family members with familial Mediterranean fever carrying the M694V mutation showed different clinical presentations.
Review
GeneRIF
Altunoglu et al., Turkey. In Intern Med, 2011
Report 3 sibling FMF patients who have the M694V mutation with different clinical presentations. While the sister presented with abdominal pain, one of the brothers presented with erysipelas-like erythema and the other brother with bilateral sacroiliitis.
Familial mediterranean fever in Arabs.
Review
Impact
El-Khateeb et al., Iowa City, United States. In Lancet, 2006
Familial Mediterranean fever (FMF) is an archetypal autoinflammatory disorder, which is autosomal recessive and has a high prevalence in non-Ashkenazi Jews, Armenians, Turks, and Arabs.
Mutations in the gene encoding mevalonate kinase cause hyper-IgD and periodic fever syndrome. International Hyper-IgD Study Group.
Impact
Delpech et al., Paris, France. In Nat Genet, 1999
Familial Mediterranean fever (MIM 249100) is an autosomal recessive disorder affecting mostly populations from the Mediterranean basin and is caused by mutations in the gene MEFV (refs 5,6).
A candidate gene for familial Mediterranean fever.
Impact
French FMF Consortium, In Nat Genet, 1997
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by attacks of fever and serositis.
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