Exposure to fluorescent light triggers down regulation of genes involved with mitotic progression in Xiphophorus skin.
San Marcos, United States. In Comp Biochem Physiol C Toxicol Pharmacol, Dec 2015
Exposure to FL also resulted in down-regulated transcription of many genes involved with cell cycle progression (e.g., cdc20, cdc45, cdca7b, plk1, cdk1, ccnb-3, and cdca7a) and chromosome segregation (e.g., cenpe, cenpf, cenpi, cenpk, cenpo, cenpp, and cenpu; cep70; knstrm, kntc, mcm2, mcm5; smc2).
Structure of the eukaryotic MCM complex at 3.8 Å.
Beijing, China. In Nature, Sep 2015
This narrow passageway, reinforced by the offset of the two single hexamers at the double hexamer interface, is flanked by two pairs of gate-forming subunits, MCM2 and MCM5.
A Taxonomic Revision of the Wallemia sebi Species Complex.
Ljubljana, Slovenia. In Plos One, 2014
In this study, multi-locus phylogenetic analyses, using the internal transcribed spacer (ITS) regions, DNA replication licensing factor (MCM7), pre-rRNA processing protein (TSR1), RNA polymerase II largest subunit (RPB1), RNA polymerase II second largest subunit (RPB2) and a new marker 3´-phosphoadenosine-5´-phosphatase (HAL2), confirmed the previous hypothesis that W. sebi presents a complex of at least four species.
DNA replication, development and cancer: a homeotic connection?
Pisa, Italy. In Crit Rev Biochem Mol Biol, 2010
Moreover, Hox proteins interact with geminin, a regulator of cell cycle progression, and control the interaction of this protein with the DNA replication licensing factor Ctd1. Thus, the homeotic proteins, by participating directly in the function of DNA replication origins, may provide a direct link between the accurate regulation of DNA replication required by the morphogenetic program and the deregulation of this process typical of cancer.
New transcription factors in diagnostic hematopathology.
Milano, Italy. In Adv Anat Pathol, 2007
In this review we will consider the basic biologic aspects and the applications in hematopathology of some of the lymphocyte-related TFs, including Pax5/BSAB, MUM1/IRF4, BOB1, Oct-2, T-bet, and FOXP3.