Bioinformatics analyses of differentially expressed genes associated with acute myocardial infarction.
Shenyang, China. In Cardiovasc Ther, Feb 2016
Besides, 4 transcription factors (TFs), including nuclear receptor subfamily 2, group C, member 2 (NR2C2), MYC associated factor X (MAX), general transcription factor IIIC, polypeptide 2, beta 110 kDa (GTF3C2), and B-cell CLL/lymphoma 3 (BCL3) were identified.
The MYC-WDR5 Nexus and Cancer.
Nashville, United States. In Cancer Res, Nov 2015
The ability of MYC to regulate transcription depends on its dimerization with MAX, which creates a DNA-binding domain that recognizes specific sequences in the regulatory elements of MYC target genes.
Impact of MYC in regulation of tumor cell metabolism.
Stockholm, Sweden. In Biochim Biophys Acta, May 2015
The MYC proto-oncoproteins including c-MYC, MYCN and MYCL exert their functions as heterodimers with MAX, which in turn binds to E-box sequences at target promoters to regulate gene expression.
Paragangliomas/Pheochromocytomas: clinically oriented genetic testing.
Faro, Portugal. In Int J Endocrinol, 2013
Additionally to the genes involved in the classical syndromic forms: VHL gene (von Hippel-Lindau), RET gene (Multiple Endocrine Neoplasia type 2), and NF1 gene (Neurofibromatosis type 1), 10 novel genes have so far been implicated in the occurrence of paragangliomas/pheochromocytomas: SDHA, SDHB, SDHC, SDHD, SDHAF2, TMEM127, MAX, EGLN1, HIF2A, and KIF1B.