Bioinformatics analyses of differentially expressed genes associated with acute myocardial infarction.
Shenyang, China. In Cardiovasc Ther, Feb 2016
Besides, 4 transcription factors (TFs), including nuclear receptor subfamily 2, group C, member 2 (NR2C2), MYC associated factor X (MAX), general transcription factor IIIC, polypeptide 2, beta 110 kDa (GTF3C2), and B-cell CLL/lymphoma 3 (BCL3) were identified.
The MYC-WDR5 Nexus and Cancer.
Nashville, United States. In Cancer Res, Nov 2015
The ability of MYC to regulate transcription depends on its dimerization with MAX, which creates a DNA-binding domain that recognizes specific sequences in the regulatory elements of MYC target genes.
Impact of MYC in regulation of tumor cell metabolism.
Stockholm, Sweden. In Biochim Biophys Acta, May 2015
The MYC proto-oncoproteins including c-MYC, MYCN and MYCL exert their functions as heterodimers with MAX, which in turn binds to E-box sequences at target promoters to regulate gene expression.
Pheochromocytoma and paraganglioma.
In Endocr Pract, Apr 2015
ABBREVIATIONS: HIF2A = hypoxia-inducible factor 2α MAX = Myc-associated factor X MEN2 = multiple endocrine neoplasia type 2 NF1 = neurofibromatosis type 1 PGL = paraganglioma PHEO = pheochromocytoma SDHAF2 = succinate dehydrogenase complex assemble factor 2 TMEM127 = transmembrane protein 127 VHL = von Hippel-Lindau.