Sequence information gain based motif analysis.
Barcelona, Spain. In Bmc Bioinformatics, 2014
SIGMA has been compared with different publicly available alternatives for motif detection, such as MEME/MAST, Biostrings (Bioconductor package), MotifRegressor, and previous work such Qresiduals projections or information theoretic based detectors.
AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases.
Frankfurt am Main, Germany. In Biochim Biophys Acta, 2013
The group of AGC protein kinases includes more than 60 protein kinases in the human genome, classified into 14 families: PDK1, AKT/PKB, SGK, PKA, PKG, PKC, PKN/PRK, RSK, NDR, MAST, YANK, DMPK, GRK and SGK494.
Review and international recommendation of methods for typing neisseria gonorrhoeae isolates and their implications for improved knowledge of gonococcal epidemiology, treatment, and biology.
Örebro, Sweden. In Clin Microbiol Rev, 2011
Currently, for microepidemiological questions, the best methods for fast, objective, portable, highly discriminatory, reproducible, typeable, and high-throughput characterization are N. gonorrhoeae multiantigen sequence typing (NG-MAST) or full- or extended-length porB gene sequencing.
The nuts and bolts of AGC protein kinases.
Dundee, United Kingdom. In Nat Rev Mol Cell Biol, 2010
The family comprises some intensely examined protein kinases (such as Akt, S6K, RSK, MSK, PDK1 and GRK) as well as many less well-studied enzymes (such as SGK, NDR, LATS, CRIK, SGK494, PRKX, PRKY and MAST).
Cell division: MAST sails through mitosis.
United States. In Curr Biol, 2002
A recent study implicates the microtubule-associated protein MAST/Orbit in a surprisingly wide array of mitotic activities, ranging from maintaining mitotic spindle bipolarity to tethering chromosomes to the ends of microtubules.