mast cell carboxypeptidase A
[Diagnostic Significance of BAT in Anaphylaxis to Non-ionic Contrast Media].
In Fa Yi Xue Za Zhi, Jun 2015
OBJECTIVE: To investigate the diagnostic significance of basophil activation test (BAT) in anaphylaxis to non-ionic contrast media through testing the content of CD63, mast cell-carboxypeptidase A3 (MC-CPA3), and terminal complement complex SC5b-9 of the individuals by testing their levels in the normal immune group and the anaphylaxis groups to β-lactam drugs and non -ionic contrast media.
Mast cell proteases as pharmacological targets.
San Francisco, United States. In Eur J Pharmacol, Jun 2015
In terms of relative amounts, the major mast cell proteases include the tryptases, chymases, cathepsin G, carboxypeptidase A3, dipeptidylpeptidase I/cathepsin C, and cathepsins L and S. Some mast cells also produce granzyme B, plasminogen activators, and matrix metalloproteinases.
Mast cell proteases as protective and inflammatory mediators.
San Francisco, United States. In Adv Exp Med Biol, 2010
In other life-or-death examples, carboxypeptidase A3 and other mast cell peptidases limit systemic toxicity of endogenous peptideslike endothelin and neurotensin during septic peritonitis and inactivate venom-associated peptides.
In vitro diagnosis of anaphylaxis.
Pamplona, Spain. In Chem Immunol Allergy, 2009
The in vitro diagnosis of anaphylaxis includes, among other aspects, the serial measurement of mediators which are released in the course of an anaphylactic reaction such as tryptase, histamine, chymase, carboxypeptidase A3, platelet-activating factor and other products from mastocytes.