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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

MAS1 oncogene

MAS
The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Angiotensin II, CAN, Renin, ACE2, V1a
Papers using MAS antibodies
Heme oxygenase-1 suppresses the infiltration of neutrophils in rat liver during sepsis through inactivation of p38 MAPK
Supplier
Hong Ma et al., In International Journal of Hypertension, 2009
... The peptides Ang II and the Ang-(1–7) Mas receptor antagonist A779 were obtained from Bachem (King of Prussia, PA, ...
Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries
Supplier
Jones E. S. et al., In International Journal of Hypertension, 2003
... MasR (Novus Biologicals, USA, Catalogue no ...
Activated skin mast cells are involved in murine hair follicle regression (catagen).
Supplier
Kumar Nirbhay, In PLoS ONE, 1996
... Mice expressing the human DTR under the control of IE element (for Mas-TRECK) and 3′UTR element (for Bas-TRECK) in the Il4 locus were generated by a transgenic strategy ...
Papers on MAS
Spectral editing at ultra-fast magic-angle-spinning in solid-state NMR: facilitating protein sequential signal assignment by HIGHLIGHT approach.
New
Ishii et al., Chicago, United States. In J Biomol Nmr, Feb 2016
UNASSIGNED: This study demonstrates a novel spectral editing technique for protein solid-state NMR (SSNMR) to simplify the spectrum drastically and to reduce the ambiguity for protein main-chain signal assignments in fast magic-angle-spinning (MAS) conditions at a wide frequency range of 40-80 kHz.
Resistance training prevents the cardiovascular changes caused by high-fat diet.
New
Colombari et al., São Paulo, Brazil. In Life Sci, Feb 2016
The anti-inflammatory interleukin-10, angiotensin type 2 receptor, Mas receptor and angiotensin converting enzyme 2 mRNA expressions in the NTS increased in the RT-HFD compared to SED-HFD.
[Visceral leishmaniasis without splenomegaly. A pediatric case report].
New
De Pontual et al., Bondy, France. In Arch Pediatr, Feb 2016
A secondary macrophage activation syndrome (MAS) can complicate this infection, which is lethal when not treated.
Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors.
New
Krause et al., United States. In Neuropharmacology, Feb 2016
Angiotensin converting enzyme (ACE2) inhibits RAS activity by converting angiotensin II, the effector peptide of RAS, to angiotensin-(1-7), which activates Mas receptors (MasR).
Treatment of Peripheral Precocious Puberty.
Review
New
Eugster et al., In Endocr Dev, Dec 2015
McCune-Albright syndrome (MAS) and familial male-limited precocious puberty (FMPP) represent rare causes of PPP that arise from activating mutations in GNAS1 and the LH receptor gene, respectively.
Brain angiotensin-(1-7)/Mas axis: A new target to reduce the cardiovascular risk to emotional stress.
Review
New
Santos et al., Belo Horizonte, Brazil. In Neuropeptides, Nov 2015
On the other hand, growing evidence indicates that its counterregulatory axis, the angiotensin-converting enzyme 2 (ACE2)/(Ang)iotensin-(1-7)/Mas axis, reduces anxiety and attenuates the physiological responses to emotional stress.
International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].
Review
New
Impact
Thomas et al., Seychelles. In Pharmacol Rev, Oct 2015
The receptors for RAS peptides consist of three G-protein-coupled receptors—the angiotensin II type 1 receptor (AT1 receptor), the angiotensin II type 2 receptor (AT2 receptor), the MAS receptor—and a type II trans-membrane zinc protein—the candidate angiotensin IV receptor (AngIV binding site).
Macrophage Activation Syndrome.
Review
New
Cron et al., Genova, Italy. In Hematol Oncol Clin North Am, Oct 2015
Macrophage activation syndrome (MAS) is a potentially life-threatening complication of rheumatic disorders that occurs most commonly in systemic juvenile idiopathic arthritis.
Fibrous Dysplasia
Review
New
Boyce, Madagascar. In Unknown Journal, Oct 2015
FD may occur in isolation, or in association with skin pigmentation and hyperfunctioning endocrinopathies, termed McCune-Albright syndrome (MAS).
Therapeutic Potential of Interferon-γ and Its Antagonists in Autoinflammation: Lessons from Murine Models of Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome.
Review
Matthys et al., Leuven, Belgium. In Pharmaceuticals (basel), 2014
Here, we review the role of endogenous IFN-γ in inflammatory disorders and related murine models, with a focus on systemic juvenile idiopathic arthritis (sJIA) and macrophage activation syndrome (MAS).
High Diversity of Anaerobic Alkane-Degrading Microbial Communities in Marine Seep Sediments Based on (1-methylalkyl)succinate Synthase Genes.
Knittel et al., Bremen, Germany. In Front Microbiol, 2014
The most widely distributed mechanism of anaerobic alkane activation is the addition of alkanes to fumarate by (1-methylalkyl)succinate synthase (Mas).
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.
Impact
Goldbach-Mansky et al., Bethesda, United States. In Nat Genet, 2014
Herein we report a de novo missense mutation (c.1009A > T, encoding p.Thr337Ser) affecting the nucleotide-binding domain of the inflammasome component NLRC4 that causes early-onset recurrent fever flares and macrophage activation syndrome (MAS).
MAS and its related G protein-coupled receptors, Mrgprs.
Review
Impact
Santos et al., Berlin, Germany. In Pharmacol Rev, 2014
The Mas-related G protein-coupled receptors (Mrgprs or Mas-related genes) comprise a subfamily of receptors named after the first discovered member, Mas.
Pharmacology and signaling of MAS-related G protein-coupled receptors.
Review
Impact
Breit et al., München, Germany. In Pharmacol Rev, 2014
One decade ago, an entire new GPCR family was discovered, which was recently named MAS-related G protein-coupled receptors (MRGPR) by the HUGO Gene Nomenclature Committee.
Membrane protein structure determination in membrana.
Impact
Marassi et al., Los Angeles, United States. In Acc Chem Res, 2013
Using complementary solid-state NMR methods based on oriented sample (OS) and magic angle spinning (MAS) approaches, one can resolve and assign multiple peaks through the use of (15)N/(13)C labeled samples and measure precise restraints to determine structures.
Upregulation of ACE2-ANG-(1-7)-Mas axis in jejunal enterocytes of type 1 diabetic rats: implications for glucose transport.
GeneRIF
Leung et al., Hong Kong, Hong Kong. In Am J Physiol Endocrinol Metab, 2012
Data suggest that jejunal enterocyte protein and mRNA expression of Mas receptor and ACE2 are up-regulated in type 1 diabetes.
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
GeneRIF
Lu et al., Shanghai, China. In Regul Pept, 2012
Ang-(1-7) stimulates mesangial cells proliferation via Mas receptor.
The Mas receptor mediates modulation of insulin signaling by angiotensin-(1-7).
GeneRIF
Dominici et al., Buenos Aires, Argentina. In Regul Pept, 2012
The Mas receptor is involved in beneficial effects of Ang-(1-7) on the phosphorylation of crucial insulin signaling mediators (Akt, GSK-3beta and AS160), in liver, skeletal muscle and adipose tissue.
Possible involvement of angiotensin-converting enzyme 2 and Mas activation in inhibitory effects of angiotensin II Type 1 receptor blockade on vascular remodeling.
GeneRIF
Horiuchi et al., Japan. In Hypertension, 2012
Data show that in angiotensin II type 1a receptor knockout mice, mRNA expression and immunostaining of ACE2 and Mas in the injured artery were greater, with less neointimal formation than in wild-type mice.
The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli.
GeneRIF
Guatimosim et al., Belo Horizonte, Brazil. In Peptides, 2012
data indicate that Mas expression is responsive to different pathological stimuli, thereby suggesting that Mas receptor is involved in the homeostasis of the heart, as well as in the establishment and progression of cardiac diseases
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